32 completed, 13 unknown, 8 terminated, 3 recruiting. 21 Not applicable, 16 Phase 4, 15 Phase 2, 9 Phase 3, 3 Phase 1.
Follow Sterile water: new trials by email Literature Review of Sterile water trials Research Report on Sterile water
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Is Pain Ease (New Formula) Safe and Effective in Reducing Pain Associated With Peripheral Intravenous Cannulation (PIV)? Sterile water, Vapocoolant spray - Peripheral Intravenous Cannulation, Pain Management | Not applicable | Not yet recruiting | Gebauer Company | 100 | 2026-12-01 | 2026-09-15 |
| Betadine vs Sterile Water for Periurethral Preparation Povidone-Iodine, Sterile water - Catherization, Urinary Tract Infection Bacterial | Phase 4 | Recruiting | University of Louisville | 148 | 2025-06-30 | 2026-05-04 |
| Chlorhexidine Lavage for Recurrent Urinary Tract Infection Chlorhexidine, Sterile Water - Urinary Tract Infections, Recurrent Urinary Tract Infection | Phase 4 | Active not recruiting | Oregon Health and Science University | 136 | 2024-12-23 | 2026-01-15 |
| Be Sweet to Babies During Nasolaryngoscopy 24% Sucrose, Sterile water - Infant Conditions | Not applicable | Recruiting | The Hospital for Sick Children | 60 | 2024-09-23 | 2025-07-04 |
| Low-osmolar Water Soluble Contrast Agent in Management of Adhesive Small Bowel Obstruction Low osmolar contrast, Sterile water - Small Bowel Adhesion, Small Bowel Obstruction | Not applicable | Unknown | Queen Savang Vadhana Memorial Hospital, Thailand | 66 | 2024-06-01 | 2024-04-04 |
| Enteral Zinc Supplementation in Very Low Birth Weight Infants Zinc Sulfate, Sterile Water - Very Low Birth Weight Infant, Nutritional Deficiency | Phase 3 | Unknown | University of Tennessee | 50 | 2024-06-01 | 2024-06-06 |
| Intranasal Ketamine Effectiveness in Reducing Intramuscular Injection Pain Before Sedation Among Children Ketamine, Sterile water - Pain, Intranasal Ketamine | Phase 4 | Completed | Tehran University of Medical Sciences | 84 | 2023-12-02 | 2024-06-04 |
| Valethamate Bromide Versus Hyoscine Butyl Bromide in Reducing Labour Duration Among Primigravida Valethamate Bromide, Hyoscine butylbromide, Sterile water - Labour Duration, Primigravida | Not applicable | Completed | Federal Teaching Hospital Abakaliki | 165 | 2023-09-01 | 2026-03-16 |
| Chlorhexidine Mouthwash and Oral Nitrate in Adults With Pulmonary Hypertension Nitrates, Chlorhexidine Gluconate Mouthwash, Placebo Mouthwash - Pulmonary Hypertension, Heart Failure With Normal Ejection Fraction | Phase 1 | Withdrawn | Gladwin, Mark, MD | 2022-12-01 | 2022-07-07 | |
| Clonidine as Pain Relief During ROP Eye Examinations Clonidine Oral Liquid Product, Sterile water - Retinopathy of Prematurity, Pain, Procedural | Phase 4 | Unknown | Region Örebro County | 50 | 2022-04-25 | 2022-05-04 |
| Efficacy of Oral Rinses for Inactivation of COVID-19 (MOR2) Placebo Comparator: Sterile Water, 27% Ethanol plus essential oils, 0.075% Cetylpyridinium Chloride - COVID-19, Coronavirus Infection | Not applicable | Completed | University of North Carolina, Chapel Hill | 230 | 2022-01-20 | 2024-09-19 |
| Antiviral Efficacy and Acceptability of Mouth Rinses for Inactivation of COVID-19 Water, Peroxyl, Periogard - COVID19, Coronavirus Infection | Phase 2 | Terminated | University of North Carolina, Chapel Hill | 2 | 2021-03-26 | 2022-02-16 |
| Microbial Growth in Operative Splash Basins During Total Joint Arthroplasty Sterile Water, 3.5% Betadine, 0.05% Chlorhexidine Gluconate - Periprosthetic Joint Infection | Not applicable | Terminated | University of Southern California | 30 | 2021-01-16 | 2023-02-09 |
| The Effect of Octreotide on Wound Drainage After Mastectomy Octreotide Injection, Sterile water - Seroma Following Procedure | Phase 4 | Completed | Ikechukwu Bartholomew Ulasi | 41 | 2020-12-18 | 2023-01-18 |
| Efficacy of CPPLAI in Laparoscopic Sleeve Gastrectomy Patients CPPLAI, Placebo, Bupivacaine 0.25% - Obesity, Morbid, Pain, Postoperative | Not applicable | Completed | King Khalid University Hospital | 120 | 2020-12-08 | 2023-10-03 |
| Analgesia in Lingual Frenulotomy in the Newborn Sugar and water solution, Sterile water - Frenulum Breve | Not applicable | Completed | IRCCS Burlo Garofolo | 72 | 2020-09-18 | 2025-05-07 |
| Personalized Treatment of Urogenital Cancers Depends on the Microbiome Tigecycline 50 MG, Placebo - Microbial Disease | Not applicable | Recruiting | Zealand University Hospital | 28 | 2020-05-01 | 2024-01-30 |
| The Effects of Iontophoresed Vasoactive Drugs on Cutaneus Blood Flow Acetylcholine, Norepinephrine, Phenylephrine - Cardiovascular Diseases, Vascular Diseases | Not applicable | Terminated | University Hospital, Linkoeping | 31 | 2019-04-01 | 2026-05-13 |
| Effectiveness of Oral Immunotherapy Among Preterm Babies Sterile water, Breastmilk - Feeding Behavior, Late-Onset Neonatal Sepsis | Not applicable | Completed | Al Adan Hospital Kuwait | 48 | 2018-08-16 | 2019-07-12 |
| 10% Lidocaine Spray for Intrauterine Device Insertion lidocaine spray, Placebo - Contraception, Intrauterine Device | Phase 4 | Completed | Mahidol University | 124 | 2018-08-01 | 2020-01-30 |
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Pain (10) · Dental Plaque (4) · Pain, Procedural (3) · Periodontitis (3) · Sepsis (3) · Asthma (2) · COVID-19 (2) · Coronavirus Infections (2) · Labor Pain (2) · Neonatal Sepsis (2) · Premature Birth (2) · Retinopathy of Prematurity (2) · Status Asthmaticus (2) · Abscess (1) · Agnosia (1)
University of Santiago de Compostela (4) · GlaxoSmithKline (3) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (2) · Region Örebro County (2) · The Hospital for Sick Children (2) · University of North Carolina, Chapel Hill (2) · Ain Shams University (1) · Al Adan Hospital Kuwait (1) · All India Institute of Medical Sciences (1) · Aultman Health Foundation (1) · Bionor Immuno AS (1) · Changi General Hospital (1) · Children's Hospital Medical Center, Cincinnati (1) · Children's Hospital of Eastern Ontario (1) · Children's Hospital of Michigan (1)
United States (24) · Canada (4) · Spain (3) · Italy (2) · Mexico (2) · Nigeria (2) · Sweden (2) · Belgium (1) · Colombia (1) · Denmark (1) · Egypt (1) · Germany (1) · Greece (1) · India (1) · Iran (1)
Abbas Khani-Hanjani, MD (1) · Abdul Sattar Narejo, FCPS (1) · Ahmed E Elbohoty, MD (1) · Alison Morris, MD, MS (1) · Andrew C Mire, M.D. (1) · Ankita Gupta, MD, MPH (1) · Arthur Rawlings, MD (1) · Assumpta N Nweke (1) · Ben Dilen, MSN (1) · Bridget Wills, MD (1) · Chiara Navarra, DDS MSc PhD (1) · Cynthia Blanco, M.D. (1) · Daniel Wilhelms, Phd (1) · Denise Harrison, RN, PhD (1)
PMID 21536607, PMID 22079954, PMID 2239906, PMID 23052809, PMID 24121149, PMID 24525316, PMID 24918475, PMID 25132459, PMID 25689859, PMID 26579854, PMID 26896318, PMID 28850378, PMID 31438878, PMID 32591417, PMID 33292081, PMID 33558263, PMID 35449189, PMID 36137627
2018 (1), P01HL103455 (1)