51 completed, 23 unknown, 11 terminated, 10 recruiting. 24 Phase 4, 19 Phase 2, 17 Not applicable, 14 Phase 3, 4 Phase 1.
Follow statin: new trials by email Literature Review of statin trials Research Report on statin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Short-term Intensive Statin Therapy on Lipid Levels statin - Ischemic Stroke | Recruiting | General Hospital of Shenyang Military Region | 800 | 2026-01-08 | 2026-01-15 | |
| PCSK9 Inhibitor With Statin Therapy for Asymptomatic Intracranial Atherosclerosis Recaticimab and Statin, Statin - Intracranial Atherosclerosis, Intracranial Artery Stenosis | Phase 4 | Recruiting | Peking Union Medical College Hospital | 300 | 2025-11-07 | 2026-06-12 |
| Effects of Statins and Hormone Replacement Therapy in Coagulation Profile of Menopausal Women With Dyslipidemia estroprogestins, Statin - Menopausal Complaints, Hypercholerolemia | Recruiting | University of Pisa | 70 | 2025-10-15 | 2026-08-03 | |
| Protective Effect of PCSK9 Inhibitor Against Negative Inflammatory Response and Organ Dysfunction After Coronary Artery Bypass Grafting (PANDA VIII) PCSK9 inhibitor, Statin - Myocardial Ischaemic Syndrome, Coronary Heart Disease | Not applicable | Not yet recruiting | Nanjing Medical University | 400 | 2025-01-01 | 2024-12-12 |
| Multicenter Real-World Cohort Study Evaluating the Impact of Early Intensive Lipid-Lowering Therapy on the Prognosis of Acute Coronary Syndrome Patients(ELITE-ACS) PCSK9 inhibitor, Statin+Ezetimibe/Hybutimibe compound, Statin - Acute Coronary Syndromes | Recruiting | Yun Dai Chen | 6000 | 2024-12-16 | 2025-03-17 | |
| Statins in Frail Older Patients with Ischemic Stroke or Transient Ischemic Attack - the Prospective Cohort Study Statin - Ischemic Stroke, TIA | Recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 300 | 2024-11-01 | 2025-01-21 | |
| Efficacy of Probucol Combined with Statins Treatment for Ischemic Stroke Statin, Probucol - Ischemic Stroke, Atherosclerosis of Artery | Recruiting | Xuanwu Hospital, Beijing | 200 | 2024-10-17 | 2025-03-25 | |
| Statins Effect on Incidence of Side Effects of Platinum Based Chemotherapy Statin - Solid Tumors, Ototoxicity | Phase 1 / Phase 2 | Completed | Minia University | 56 | 2024-09-01 | 2026-01-20 |
| Effect of SLC01B1 (rs4149956) Polymorphism on the Efficacy and Tolerability of Atorvastatin in Pakistani Population Atorvastatin - Hyperlipidemias | Completed | Riphah International University | 150 | 2024-09-01 | 2025-08-29 | |
| Effect of PCSK9 Inhibitors on Coronary Atherosclerotic Plaques Derived From Optical Coherence Tomography PCSK9 inhibitor, Statin - Coronary Artery Disease, Optical Coherence Tomography | Phase 4 | Recruiting | First Affiliated Hospital of Xinjiang Medical University | 396 | 2024-07-01 | 2024-08-19 |
| An Exploratory Clinical Study of Statins for Improving Chemotherapy and Maintenance in Patients With Ovarian Cancer Statin, Sugar pill - Ovarian Cancer | Phase 2 | Unknown | Anhui Provincial Cancer Hospital | 500 | 2024-06-30 | 2024-06-21 |
| AdLip: Human Coach-supported Digital/AI Personal Health Assistant to Improve Adherence to Lipid-Lowering Medication Human Coach-supported Digital/AI Personal Health Assistant to Improve Adherence to Lipid-Lowering Medications - Hyperlipidemia, Medication Nonadherence | Not applicable | Unknown | National University of Singapore | 450 | 2024-06-10 | 2024-10-03 |
| Aggressive Risk-Prevention Therapies for Coronary Atherosclerotic Plaque (ART-CAP) Statin, Aspirin tablet, Nexlizet - Coronary Artery Disease, Atherosclerosis | Phase 4 | Withdrawn | University of Louisville | 2024-03-01 | 2025-03-17 | |
| Adjunctive Role of Statin Therapy on Airway Inflammation and Clinical Consequences of Chronic Obstructive Pulmonary Disease Statin, placepo intervention - Statin, Airway Disease | Not applicable | Completed | Mohamed Salah El-Sayed | 80 | 2024-01-01 | 2026-04-24 |
| Early Initiation of Tafolecimab for Patients With Acute Coronary Syndromeundergoing Percutaneous Coronary Intervention in Chinese Population Tafolecimab, Cholesterol Absorption Inhibitor, Statin - Acute Coronary Syndrome, Non ST Segment Elevation Acute Coronary Syndrome | Phase 4 | Recruiting | China National Center for Cardiovascular Diseases | 3684 | 2023-11-11 | 2026-10-27 |
| Study on the Composite Endpoint Event of PCSK9 Inhibitor in Patients With Very High Risk of ASCVD and Cancer Evolocumab, Statin - ASCVD, Atherosclerotic Cardiovascular Disease | Phase 4 | Unknown | Xiang Xie | 620 | 2023-08-01 | 2023-08-04 |
| Oral Statins and Protection From Hearing Loss Statin, methylprednisolone, dexamethasone - Sudden Sensorineural Hearing Loss | Phase 4 | Terminated | Northwestern University | 3 | 2023-02-09 | 2026-10-29 |
| High Risk Population of Cardiovascular Disease in Hubei Province Screening and Intervention Program phone calls and encouraging patients' lifestyle change and medication adherence, Statin - Cardiovascular Diseases, Diabetes Mellitus, Type 2 | Not applicable | Unknown | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 16000 | 2023-01-15 | 2023-12-15 |
| Effect of Evolocumab on Chronic Total Occlusions (EVOLO-CTO) PCSK9 inhibitor, Statin - In-stent Restenosis, Major Adverse Cardiovascular Events | Phase 4 | Unknown | Lin Zhao | 200 | 2022-12-15 | 2023-11-13 |
| Vascular Endothelial Dysfunction in Sleep Apnea Atorvastatin 10mg, Placebo, Continuous Positive Airway Pressure Therapy - Obstructive Sleep Apnea of Adult | Phase 1 | Recruiting | Columbia University | 110 | 2022-10-03 | 2026-02-13 |
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Hypercholesterolemia (13) · Ischemic Stroke (9) · Myocardial Infarction (8) · Atherosclerosis (7) · Dyslipidemias (7) · Hyperlipidemias (6) · Acute Coronary Syndrome (5) · Cardiovascular Diseases (5) · Coronary Artery Disease (5) · Coronary Disease (5) · Stroke (5) · Hypertension (3) · Neoplasms (3) · Angina Pectoris, Variant (2) · Angina, Unstable (2)
Organon and Co (4) · Columbia University (3) · NYU Langone Health (2) · National Taiwan University Hospital (2) · Peking Union Medical College Hospital (2) · Tongji Hospital (2) · Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan (2) · University of Sao Paulo General Hospital (2) · Yonsei University (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Alaa Hassan ElBaz (1) · Albert Einstein Healthcare Network (1) · Alfa Wassermann Tunisia (1) · Anhui Provincial Cancer Hospital (1) · Antalya Training and Research Hospital (1)
United States (22) · China (21) · Canada (7) · Brazil (5) · Japan (4) · South Korea (4) · Taiwan (4) · Egypt (3) · Netherlands (3) · United Kingdom (3) · Australia (2) · Indonesia (2) · Italy (2) · Spain (2) · Bosnia and Herzegovina (1)
Jeffrey Berger, MD (2) · Masayasu Matsumoto, MD, PhD (2) · Sanja Jelic, MD (2) · Yong Huo, MD (2) · Ahmed Abdel-Galeel, MD (1) · Andrei C Sposito, MD, PhD (1) · Andria Priyana, MD, FIHA (1) · Andy Hau Yan Ho (1) · Andy Khong (1) · Angela F Sunjaya (1) · Anil Bhansali, DM (1) · Annapoorna Kini, MD (1) · Anthony P Sunjaya (1) · Ayman Ibrahem, MD (1) · Behnood Bikdeli, MD, MS (1)
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R01HL106041 (2), 2023 (1), R01CA218486 (1), R34HL143279 (1)