27 completed, 13 unknown, 5 not yet recruiting, 3 recruiting. 16 Not applicable, 12 Phase 2, 10 Phase 3, 8 Phase 4, 6 Phase 1.
Follow Sodium Hyaluronate: new trials by email Literature Review of Sodium Hyaluronate trials Research Report on Sodium Hyaluronate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase II/III Randomized Trial of UC-MSC Secretome vs Sodium Hyaluronate in Knee Osteoarthritis UC-MSC-Derived Secretome, Sodium Hyaluronate (Hyalein) - Knee Osteoarthritis (Knee OA) | Phase 2 / Phase 3 | Not yet recruiting | Universitas Sriwijaya | 50 | 2026-08-30 | 2026-05-12 |
| Clinical Trial to Evaluate the Efficacy and Safety of Conjuran® After First and Second Cycle (Repeat) Administration in Patients With Knee Osteoarthritis Conjuran, Hyruan - Knee Osteoarthritis | Not applicable | Not yet recruiting | PharmaResearch Co.,Ltd | 180 | 2026-06-01 | 2026-06-12 |
| Clinical Study of i-PRF Intrauterine Perfusion for Endometrial Regeneration and Repair in Moderate to Severe Intrauterine Adhesions Injectable Platelet-Rich Fibrin, Sodium Hyaluronate - Intrauterine Adhesions | Not applicable | Not yet recruiting | Beijing Obstetrics and Gynecology Hospital | 200 | 2026-05-01 | 2026-04-17 |
| Clinical Investigation of Sensovisc Sensovisc® - Osteo Arthritis of the Knee | Not applicable | Not yet recruiting | Ankara City Hospital Bilkent | 75 | 2025-11-25 | 2025-11-20 |
| A-PRF AND HA AFTER IMPACTED THIRD MOLAR SURGERY Advanced Platelet-Rich Fibrin, Sodium hyaluronate - Third Molar Surgery | Not applicable | Completed | Inonu University | 47 | 2025-08-11 | 2026-09-29 |
| Ganyan-1 in Dry Eye Ganyan1, Sodium Hyaluronate, 1/2Ganyan1 - Dry Eye, TCM | Not applicable | Not yet recruiting | Beijing Tongren Hospital | 219 | 2025-07-01 | 2025-06-25 |
| Safety and Efficacy Evaluation of Sodium Hyaluronate 32mg/ml in Improving Facial Skin Dryness and Dullness Sodium Hyaluronate - Facial Dryness, Facial Dullness | Not applicable | Recruiting | IBSA Farmaceutici Italia Srl | 500 | 2025-02-19 | 2025-04-06 |
| Comparing Methylprednisolone And Hyaluronic Acid To Reduce Wisdom Tooth Surgery Complications Methyl Prednisolone (MP), Hyaluronic Acid (HA) - Wisdom Tooth Removal, Post Operative Complications | Phase 3 | Enrolling by invitation | Sana'a University | 40 | 2024-06-27 | 2026-04-30 |
| Injectable Platelet-Rich Fibrin Versus Hyaluronic Acid for Thin Gingival Phenotype Injectable Platelet Rich Fibrin, Hyaluronic Acid - Thin Gingival Phenotype | Not applicable | Completed | University of Yaounde 1 | 11 | 2024-06-10 | 2026-10-19 |
| Efficacy of Hyaluronic Acid in Prevention of Acute Radiation Proctitis Hyaluronic Acid, Placebo - Acute Radiation Proctitis, Acute Radiation Enteritis | Phase 1 / Phase 2 | Completed | Assiut University | 44 | 2024-04-01 | 2025-01-22 |
| The Role of Butirprost® in Combination With Antibiotics in Chronic Bacterial Prostatitis (CBP) Treatment Sodium Hyaluronate, Levofloxacin 500mg - Prostate Inflammation, Prostate Disease | Phase 3 | Completed | Federico II University | 60 | 2024-03-01 | 2024-11-18 |
| Efficacy of Hyaluronic Acid Injection in Knee Osteoarthritis Sodium Hyaluronate, Normal Saline, Triamcinolone Acetonide 10mg/mL - Knee Osteoarthritis, Pain, Joint | Phase 4 | Unknown | Phramongkutklao College of Medicine and Hospital | 176 | 2024-02-10 | 2024-02-28 |
| Assessing the Effectiveness and Safety of Interferon Bladder Infusion for the Treatment of Interstitial Cystitis Interferon, Sodium Hyaluronate, Sodium Chloride Injection - Interstitial Cystitis | Phase 2 / Phase 3 | Unknown | West China Hospital | 129 | 2023-10-15 | 2023-09-15 |
| HA35 Moderate Alcoholic Hepatitis (AH) Study Sodium Hyaluronate, Placebo - Alcoholic Hepatitis | Early Phase 1 | Recruiting | The Cleveland Clinic | 54 | 2022-09-01 | 2026-09-24 |
| Effect of Various Treatment Modalities on Dendritic Vial Ulcer Acyclovir, Tobramycin, Fluorometholone - Corneal Ulcer | Unknown | Sohag University | 40 | 2022-03-18 | 2022-04-06 | |
| HA35 Acute Alcohol Study Sodium Hyaluronate, Placebo - Healthy Controls | Early Phase 1 | Recruiting | The Cleveland Clinic | 24 | 2022-02-01 | 2026-09-24 |
| Performance and Safety of Routine Cataract Surgery With Visiol Visiol - Following Cataract Surgery | Completed | TRB Chemedica | 100 | 2022-01-27 | 2023-11-22 | |
| Wireless Micropump in Dry Eye Patients Sodium Hyaluronate - Dry Eye | Not applicable | Unknown | Tianjin Eye Hospital | 20 | 2020-12-01 | 2020-12-16 |
| Combined Effect of Insulin and Sodium Hyaluronate Injection Guided by Ultrasound in Carpal Tunnel Syndrome Insulin, Sodium Hyaluronate, Ultrasound - Carpal Tunnel Syndrome | Early Phase 1 | Unknown | Assiut University | 90 | 2019-11-01 | 2019-10-29 |
| Prolotherapy Intervention Effect in Patient With Knee Osteoarthritis Prolotherapy, Sodium Hyaluronate - Knee Osteoarthritis | Phase 4 | Completed | Hasanuddin University | 36 | 2019-09-01 | 2020-11-19 |
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Osteoarthritis, Knee (12) · Dry Eye Syndromes (11) · Osteoarthritis (6) · Carpal Tunnel Syndrome (2) · Pain (2) · Alveolar Bone Loss (1) · Arthralgia (1) · Capillary Malformations, Congenital, 1 (1) · Corneal Ulcer (1) · Cystitis, Interstitial (1) · Glaucoma (1) · Gynatresia (1) · Hepatitis, Alcoholic (1) · Intervertebral Disc Degeneration (1) · Low Back Pain (1)
Assiut University (3) · Dompé Farmaceutici S.p.A (2) · Ferring Pharmaceuticals (2) · Shanghai AbelZeta Ltd. (2) · The Cleveland Clinic (2) · Affiliated Hospital of Jiangsu University (1) · Alcon Research (1) · Allergan (1) · Anika Therapeutics, Inc. (1) · Ankara City Hospital Bilkent (1) · Beijing Obstetrics and Gynecology Hospital (1) · Beijing Tongren Hospital (1) · CAR-T (Shanghai) Biotechnology Co., Ltd. (1) · Chang Gung Memorial Hospital (1) · Daiichi Sankyo (1)
United States (10) · China (8) · Egypt (4) · Italy (3) · Thailand (3) · Canada (2) · France (2) · Indonesia (2) · Taiwan (2) · Cameroon (1) · Iran (1) · Japan (1) · Mexico (1) · Norway (1) · South Korea (1)
Amal Y Al-Eryani (1) · Anderson Ferreira, Professor (1) · AssocProf Pinnita Tanthuvanit, MD (1) · Christopher Ketcherside, MD (1) · Chunde Bao, MD (1) · Dongbao Zhao, Doctor (1) · Farnaz Dehghan, MD (1) · Flavio Mantelli, MD (1) · Flavio Mantelli, MD-PhD (1) · Huang Yu Chi, Bachelor (1) · Joseph E DeCaria, BA, MSc('09) (1) · Joseph J Ruane, DO (1)
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