15 completed, 12 unknown, 6 recruiting, 2 not yet recruiting. 31 Phase 1, 12 Phase 2, 2 Not applicable, 1 Early Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of C-CAR168 in the Treatment of Autoimmune Diseases Refractory to Standard Therapy CD20/BCMA-directed CAR-T cells Autologous 2nd generation - Multiple Sclerosis (MS), Myasthenia Gravis (MG) | Phase 1 | Not yet recruiting | The Affiliated Hospital of Qingdao University | 18 | 2026-07-01 | 2026-06-30 |
| A Study of C-CAR168 in the Treatment of Central Nervous System Autoimmune Diseases Refractory to Standard Therapy CD20/BCMA-directed CAR-T cells - Multiple Sclerosis (MS), Neuromyelitis Optica Spectrum Disorders (NMOSD) | Phase 1 | Not yet recruiting | Huashan Hospital | 15 | 2026-02-01 | 2026-01-15 |
| A Phase I Trial of A-CAR032 in Participants With mCRPC dnTGFβRII-armoured STEAP2-targeted autologous CAR T-Cell Injection - Prostate Cancer, Metastatic Castration-Resistant Prostate Cancer | Phase 1 | Recruiting | Shanghai AbelZeta Ltd. | 27 | 2026-01-13 | 2026-10-16 |
| A Study of A-CAR028 Treatment in Subjects With Relapsed or Refractory Acute Myeloid Leukemia A-CAR028 - Acute Myeloid Leukemia (AML), CAR-T Cell Therapy | Phase 1 | Recruiting | First Affiliated Hospital of Zhejiang University | 20 | 2025-09-30 | 2025-09-30 |
| An Phase I Trial of a CAR T-cell Infusion C-CAR031 in Participants With GPC3+ Advanced/Metastatic Squamous Cell Lung Cancer C-CAR031 - Squamous Cell Lung Cancer | Phase 1 | Recruiting | Shanghai AbelZeta Ltd. | 24 | 2024-12-25 | 2026-03-03 |
| A Study to Evaluate C-CAR031 in Glypican-3 (GPC3)+ Advanced/Recurrent Hepatocellular Carcinoma (HCC) Armored and GPC3-targeted autologous CAR T-cell - Hepatocellular Carcinoma | Phase 1 / Phase 2 | Active not recruiting | Shanghai AbelZeta Ltd. | 121 | 2024-09-30 | 2026-10-13 |
| A Study of C-CAR039 (Prizloncabtagene Autoleucel) in Patients With Relapsed/Refractory Large B-Cell Lymphoma Prizloncabtagene autoleucel - Relapsed/Refractory Large B-Cell Lymphoma | Phase 1 / Phase 2 | Recruiting | Shanghai AbelZeta Ltd. | 112 | 2023-02-22 | 2025-12-31 |
| A Study of C-CAR088 in Patients With Relapsed or Refractory Multiple Myeloma B-cell maturation antigen (BCMA) directed chimeric antigen receptor (CAR)-T cell - Multiple Myeloma | Phase 1 / Phase 2 | Recruiting | Shanghai AbelZeta Ltd. | 92 | 2022-11-11 | 2023-03-24 |
| ASCT in Combination With C-CAR088 for Treating Patients With Ultra High-risk Multiple Myeloma (MM) Autologous hematopoietic stem cell transplantation, C-CAR088 - Multiple Myeloma | Phase 1 / Phase 2 | Recruiting | Institute of Hematology & Blood Diseases Hospital, China | 20 | 2022-07-14 | 2026-08-07 |
| Study of C-TIL052A Cell Therapy in Advanced Cervical Cancer Autologous Tumor Infiltrating Lymphocytes (C-TIL052A) Injection - Cervical Cancer | Phase 1 | Unknown | Fudan University | 20 | 2022-07-01 | 2022-07-28 |
| A Clinical Study of Mesenchymal Stem Cell Exosomes Nebulizer for the Treatment of ARDS low dose hMSC-Exos, medium dose hMSC-Exos, high dose hMSC-Exos - Acute Respiratory Distress Syndrome | Phase 1 / Phase 2 | Completed | Ruijin Hospital | 18 | 2020-11-30 | 2024-07-22 |
| A Study of C-CAR039 Treatment in Subjects With r/r NHL SubjectsNon-Hodgkin's Lymphoma Prizloncabtagene autoleucel - Non-Hodgkin's B-cell Lymphoma | Phase 1 | Completed | Tianjin Medical University Cancer Institute and Hospital | 7 | 2020-11-27 | 2025-05-28 |
| A Study of C-CAR039 Treatment in Subjects With r/r NHL SubjectsNon-Hodgkin's Lymphoma Prizloncabtagene Autoleucel - B-cell Non-Hodgkin's Lymphoma | Phase 1 | Completed | Peking Union Medical College Hospital | 10 | 2020-10-30 | 2025-05-23 |
| A Study of C-CAR039 Treatment in Subjects With r/r NHL Subjects Non-Hodgkin's Lymphoma Prizloncabtagene Autoleucel - Non-Hodgkin's B-cell Lymphoma | Phase 1 | Unknown | First Affiliated Hospital of Zhejiang University | 17 | 2020-08-03 | 2023-09-28 |
| A Clinical Study of Mesenchymal Progenitor Cell Exosomes Nebulizer for the Treatment of Pulmonary Infection Dosage 1 of MPCs-derived exosomes, Dosage 2 of MPCs-derived exosomes, No MPCs-derived exosomes - Drug-resistant | Phase 1 / Phase 2 | Suspended | Ruijin Hospital | 60 | 2020-07-01 | 2024-07-22 |
| the Safety and the Efficacy Evaluation of Allogenic Adipose MSC-Exos in Patients With Alzheimer's Disease low dosage MSCs-Exos administrated for nasal drip, mild dosage MSCs-Exos administrated for nasal drip, high dosage MSCs-Exos administrated for nasal drip - Alzheimer Disease | Phase 1 / Phase 2 | Unknown | Ruijin Hospital | 9 | 2020-07-01 | 2021-06-25 |
| Allogenic Adipose Tissue-Derived Mesenchymal Progenitor Cells for the Treatment of Knee Osteoarthritis Mesenchymal progenitor cells, No mesenchymal progenitor cells - Knee Osteoarthritis | Phase 2 | Completed | Shanghai AbelZeta Ltd. | 106 | 2020-05-16 | 2023-08-01 |
| A Tolerance Clinical Study on Aerosol Inhalation of Mesenchymal Stem Cells Exosomes In Healthy Volunteers 1X level of MSCs-Exo, 2X level of MSCs-Exo, 4X level of MSCs-Exo - Healthy | Phase 1 | Completed | Ruijin Hospital | 24 | 2020-03-12 | 2021-08-04 |
| A Pilot Clinical Study on Inhalation of Mesenchymal Stem Cells Exosomes Treating Severe Novel Coronavirus Pneumonia MSCs-derived exosomes - Coronavirus | Phase 1 | Completed | Ruijin Hospital | 24 | 2020-02-15 | 2020-09-07 |
| A Study Evaluating Safety and Efficacy of C-CAR039 Treatment in NHL Subjects Prizloncabtagene Autoleucel - Non-Hodgkin's B-cell Lymphoma | Phase 1 | Completed | Shanghai Tongji Hospital, Tongji University School of Medicine | 25 | 2019-11-05 | 2025-05-23 |
Showing 20 of 37. Sign in to see all of them.
Lymphoma, B-Cell (7) · Osteoarthritis, Knee (4) · Carcinoma, Hepatocellular (3) · Multiple Myeloma (3) · Recurrence (3) · Lymphoma, Large B-Cell, Diffuse (2) · Multiple Sclerosis (2) · Neuromyelitis Optica (2) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (2) · Alzheimer Disease (1) · Autoimmune Diseases of the Nervous System (1) · Coronavirus Infections (1) · Leukemia, Myeloid, Acute (1) · Liver Neoplasms (1) · Lupus Erythematosus, Systemic (1)
Hyaluronic Acid (2) · B-Cell Maturation Antigen (1) · Immunotherapy, Adoptive (1) · Injections (1) · Population Groups (1) · bis(3-bis(4-chlorophenyl)methyl-4-dimethylaminophenyl)amine (1)
China (35)
Daobin Zhou (2) · Lugui Qiu (2) · Aibin Liang, MD, Ph.D (1) · Aibin Liang, MD,Ph.D. (1) · Changqing Zhang (1) · Chengqing Yi (1) · Chengwei Chen (1) · Chunde Bao (1) · Chunde Bao, M.D. & Ph.D. (1) · Chunde Bao, MD (1) · Daobin Zhou, PhD&MD (1) · Dehui Zou (1) · Dehui Zou, M.D., PH.D. (1) · Dingwei Ye (1) · Gang Wang, MD,PhD (1)
PMID 39813680, PMID 39351902, PMID 29417902, PMID 31113476, PMID 31639063, PMID 32043426, PMID 32425926, PMID 34362494, PMID 34429860, PMID 34515338, PMID 35619189, PMID 36100310, PMID 37215108, PMID 37859748, PMID 40235521