8 completed, 4 recruiting, 3 terminated, 1 not yet recruiting. 16 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 16 | Completed 8, Recruiting 4, Terminated 3, Not yet recruiting 1 |
| Phase 2 | 2 | Not yet recruiting 1, Recruiting 1 |
Follow Single Person: new trials by email Literature Review of Single Person trials Research Report on Single Person
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Learn the Safety and Efficacy of HLX37 in Combination With Chemotherapy for First-line Treatment in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Investigational drug: HLX37 dose1, IV, Q3W, PEMBROLIZUMAB (alone or when added to a regimen above), Carboplatin (Investigator discretion) - NSCLC (Advanced Non-small Cell Lung Cancer) | Phase 2 / Phase 3 | Not yet recruiting | Shanghai Henlius Biotech | 1438 | 2026-11-30 | 2026-10-08 |
| Comparing Suprascapular Nerve Block and Interscalene Block for Post-thoracotomy Pain in Pediatric Patients. Interscalene brachial plexus block, anterior Supraclavicular nerve block, Thoracic Epidural Analgesia (TEA) only - Nerve Block/Methods | Phase 2 / Phase 3 | Recruiting | Children's Cancer Hospital Egypt 57357 | 126 | 2026-07-09 | 2026-09-01 |
| A Phase 3 Study of [177Lu]Ludotadipep for Metastatic Castration-Resistant Prostate Cancer [177-Lu]Ludotadipep, Best supportive care/standard of care (BSC/SOC) alone - Prostate Cancer, mCRPC | Phase 3 | Recruiting | FutureChem | 114 | 2026-01-26 | 2026-10-01 |
| Efficacy and Safety of High-dose Liposomal Amphotericin B for Disseminated Histoplasmosis in AIDS Single high dose of liposomal amphotericin B, L-AmB standard dose - Disseminated Histoplasma Capsulatum Infection, AIDS and Infections | Phase 3 | Recruiting | Federal University of Health Science of Porto Alegre | 279 | 2025-01-16 | 2026-07-27 |
| Apa/Enza-short Study: Shorter Treatment With Androgen Receptor Pathway Inhibitor in Patients With Low-volume Metastatic Castration-sensitive Prostate Cancer ADT plus only 12 months of ARPI, ADT plus continued ARPI - Prostate Cancer | Phase 3 | Recruiting | Nick Beije | 400 | 2024-02-20 | 2025-12-03 |
| A Phase 3 Study of TAS-205 in Patients With Duchenne Muscular Dystrophy（REACH-DMD） TAS-205 [Ambulatory Cohort] [Non-ambulatory Cohort], Placebo [Ambulatory Cohort] only - Duchenne Muscular Dystrophy | Phase 3 | Completed | Taiho Pharmaceutical Co., Ltd. | 104 | 2020-11-01 | 2026-08-17 |
| Extended Pelvic Lymph Node Dissection vs. no Pelvic Lymph Node Dissection at Radical Prostatectomy for intermediate-and High-risk Prostate Cancer Radical prostatectomy (RP) followed by ePLND, Radical prostatectomy (RP) only - Prostate Cancer | Phase 3 | Terminated | Swiss Cancer Institute | 57 | 2019-08-27 | 2023-03-09 |
| Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial - Hemodynamics (CREST-H) Revascularization, Intensive Medical Management (IMM) alone - Internal Carotid Artery Stenosis, Cognitive Impairment | Phase 3 | Completed | Columbia University | 392 | 2018-01-18 | 2026-08-18 |
| Microbiota Restoration Therapy for Recurrent Clostridium Difficile Infection (PUNCHCD3) RBX2660, Placebo, Open label RBX2660 (only for confirmed CDI recurrence) - Clostridium Difficile Infection (CDI) | Phase 3 | Completed | Rebiotix Inc. | 320 | 2017-07-31 | 2024-07-10 |
| Evaluation of Lanreotide Efficacity in High Output Stoma: a Multicentric Randomized Study Effects of lanreotide with current anti-diarrheal treatments (diosmectite and loperamide), Effects of current anti-diarrheal treatments (diosmectite and loperamide) alone - High Output Stoma | Phase 3 | Terminated | University Hospital, Strasbourg, France | 19 | 2015-10-22 | 2018-03-07 |
| Interest of the Injection of Morphine, in Addition to a Local Anesthetic When Performing a Combined Spinal-epidural for Labor Analgesia experimental group : sequential combined spinal epidural with local anesthetic injection (chirocaine) associated with morphine (sufentanil)., control group : sequential combined spinal epidural with local anesthetic injection (chirocaine) alone. - Pregnant Women | Phase 3 | Completed | CHU de Reims | 144 | 2014-08-01 | 2018-01-09 |
| Intervention With Vitamin D and Omega-3 Supplements and Incident Heart Failure Vitamin D and fish oil, Fish oil (EPA/DHA) alone, Vitamin D alone - Heart Failure | Phase 3 | Completed | Brigham and Women's Hospital | 25871 | 2014-08-01 | 2022-03-18 |
| Tolerability and Safety of Immune Globulin Subcutaneous Solution (IGSC) and rHuPH20 in PID SC treatment with IGSC, 10% with rHuPH20 followed by SC/IGSC, 10% only (safety), SC treatment with IGSC, 10% with rHuPH20 followed by IV/IGSC, 10% only (safety), IV treatment with IGSC, 10% - Primary Immunodeficiency Diseases (PID) | Phase 3 | Completed | Baxalta now part of Shire | 66 | 2010-07-28 | 2021-05-19 |
| Cancer Vaccine Study for Stage III, Unresectable, Non-small Cell Lung Cancer (NSCLC) in the Asian Population Tecemotide, Single low dose cyclophosphamide, Placebo - Non-Small Cell Lung Cancer | Phase 3 | Terminated | Merck KGaA, Darmstadt, Germany | 285 | 2009-12-01 | 2016-10-26 |
| Cancer Vaccine Study for Unresectable Stage III Non-small Cell Lung Cancer (START) Tecemotide (L-BLP25), Single low dose cyclophosphamide, Placebo - Non-small Cell Lung Cancer | Phase 3 | Completed | EMD Serono | 1513 | 2007-01-01 | 2015-11-20 |
| Trial of Decitabine in Patients With Acute Myeloid Leukemia Cytarabine or Supportive Care, Dacogen (decitabine) only - Acute Myeloid Leukemia | Phase 3 | Completed | Eisai Inc. | 485 | 2005-11-01 | 2019-09-11 |
Carcinoma, Non-Small-Cell Lung (3) · Prostatic Neoplasms (3) · Acquired Immunodeficiency Syndrome (1) · Carotid Stenosis (1) · Clostridium Infections (1) · Cognitive Dysfunction (1) · Diarrhea (1) · Enterocolitis, Pseudomembranous (1) · Genital Diseases (1) · Genital Neoplasms, Male (1) · Heart Failure (1) · Histoplasmosis (1) · Infections (1) · Leukemia, Myeloid, Acute (1) · Male Urogenital Diseases (1)
Baxalta now part of Shire (1) · Brigham and Women's Hospital (1) · CHU de Reims (1) · Children's Cancer Hospital Egypt 57357 (1) · Columbia University (1) · EMD Serono (1) · Eisai Inc. (1) · Federal University of Health Science of Porto Alegre (1) · FutureChem (1) · Merck KGaA, Darmstadt, Germany (1) · Nick Beije (1) · Rebiotix Inc. (1) · Shanghai Henlius Biotech (1) · Swiss Cancer Institute (1) · Taiho Pharmaceutical Co., Ltd. (1)
United States (6) · Canada (4) · France (4) · China (3) · South Korea (3) · Taiwan (3) · Australia (2) · Brazil (2) · Czechia (2) · Hong Kong (2) · Hungary (2) · Mexico (2) · Netherlands (2) · Poland (2) · Romania (2)
Cyrill A. Rentsch, MD-PhD (1) · Daiane F Dalla Lana, PhD (1) · David S Liebeskind, MD (1) · E Sander Connolly, MD (1) · Ji Youl Lee (1) · Luana C Genz Bazana, PhD (1) · Randolph S Marshall, MD (1) · Renata B Ascenco Soares, PhD (1) · Ronald M Lazar, PhD (1) · Suzan Adlan Khedr (1)
PMID 34870327, PMID 21982342, PMID 24331154, PMID 24498872, PMID 24976972, PMID 25722382, PMID 27220317, PMID 34931880, PMID 36287379, PMID 37232940, PMID 37564743, PMID 38236515, PMID 39172632, PMID 40552763, PMID 40672762, PMID 41115624, PMID 41245385, PMID 41608800, PMID 42286373, PMID 42747834
R01NS097876 (1)