9 not yet recruiting, 7 recruiting, 5 completed, 3 unknown. 23 Not applicable, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 23 | Not yet recruiting 8, Recruiting 7, Completed 5, Unknown 3 |
| Early Phase 1 | 1 | Not yet recruiting 1 |
Follow sham transcutaneous auricular vagus nerve stimulation: new trials by email Literature Review of sham transcutaneous auricular vagus nerve stimulation trials Research Report on sham transcutaneous auricular vagus nerve stimulation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Understanding Non-invasive Vagus Nerve Stimulation Effects in PTSD transcutaneous auricular vagus nerve stimulation, sham transcutaneous auricular vagus nerve stimulation - PTSD - Post Traumatic Stress Disorder | Early Phase 1 | Not yet recruiting | Wayne State University | 60 | 2027-04-01 | 2026-07-13 |
| Transcutaneous Auricular Vagus Nerve Stimulation as a Treatment for Neuropathic Pain Following Spinal Cord Injury Active Transcutaneous Auricular Vagus Nerve Stimulation, Sham Transcutaneous Auricular Vagus Nerve Stimulation - Spinal Cord Injury, Neuropathic Pain | Not applicable | Not yet recruiting | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 32 | 2026-10-01 | 2026-05-15 |
| Transcutaneous Auricular Vagus Nerve Stimulation as a Treatment for Musculoskeletal Pain in Cerebral Palsy Active Transcutaneous Auricular Vagus Nerve Stimulation, Sham Transcutaneous Auricular Vagus Nerve Stimulation - Cerebral Palsy (CP), Musculoskeletal Pain | Not applicable | Not yet recruiting | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 32 | 2026-10-01 | 2026-05-13 |
| Transcutaneous Auricular Vagus Nerve Stimulation for Recovery of Consciousness After Surgery for Spontaneous Intracerebral Hemorrhage Active Transcutaneous Auricular Vagus Nerve Stimulation, Sham Transcutaneous Auricular Vagus Nerve Stimulation - Disorders of Consciousness, Spontaneous Intracerebral Hemorrhage | Not applicable | Recruiting | Beijing Tiantan Hospital | 160 | 2026-08-01 | 2026-08-12 |
| Transcutaneous Auricular Vagus Nerve Stimulation Added to Rehabilitation for Complex Regional Pain Syndrome Type I Active Transcutaneous Auricular Vagus Nerve Stimulation, Sham Transcutaneous Auricular Vagus Nerve Stimulation, Standard Rehabilitation Program - Complex Regional Pain Syndrome Type I | Not applicable | Not yet recruiting | Liv Hospital Vadistanbul | 20 | 2026-07-15 | 2026-07-17 |
| The Efficacy and Safety of Transcutaneous Auricular Vagus Nerve Stimulation for Depression in PD Active Transcutaneous auricular vagus nerve stimulation, Sham Transcutaneous auricular vagus nerve stimulation - Parkinson Disease | Not applicable | Not yet recruiting | The First Affiliated Hospital with Nanjing Medical University | 30 | 2026-07-01 | 2026-07-01 |
| Trans Auricular Vagal Nerve Stimulation in Patients With IBS-C Transcutaneous Auricular Vagus Nerve Stimulation (ta-VNS), Sham Transcutaneous Auricular Vagus Nerve Stimulation - Irritable Bowel Syndrome (IBS-C) | Not applicable | Not yet recruiting | West Virginia University | 80 | 2026-07-01 | 2026-06-23 |
| Transcutaneous Auricular Vagus Nerve Stimulation Added to Physiotherapy for Adhesive Capsulitis Active Transcutaneous Auricular Vagus Nerve Stimulation (taVNS), Conventional Physiotherapy, Sham Transcutaneous Auricular Vagus Nerve Stimulation - Adhesive Capsulitis of the Shoulder | Not applicable | Recruiting | Muhsin Doran | 40 | 2026-06-10 | 2026-07-17 |
| Transcutaneous Auricular Vagus Nerve Stimulation in Type 2 Diabetes With Mild Cognitive Impairment active transcutaneous auricular vagus nerve stimulation, sham transcutaneous auricular vagus nerve stimulation - Type 2 Diabetes, Mild Cognitive Impairment | Not applicable | Not yet recruiting | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 38 | 2026-05-20 | 2026-06-11 |
| Association of VAgus Nerve Stimulation and Treadmill Training for GAit Rehabilitation in DE Novo Parkinson's Disease Transcutaneous Auricular Vagus Nerve Stimulation (taVNS), Sham Transcutaneous Auricular Vagus Nerve Stimulation (Sham taVNS), Conventional Physical Therapy (cPT) - Idiopathic Parkinson's Disease (PD) | Not applicable | Recruiting | Fondazione Policlinico Universitario Campus Bio-Medico | 60 | 2026-02-14 | 2026-07-16 |
| Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Postoperative Opioid Consumption in Patients Undergoing Major Abdominal Surgery Transcutaneous auricular vagus nerve stimulation, Sham Transcutaneous auricular vagus nerve stimulation - Pain Management | Not applicable | Not yet recruiting | Affiliated Hospital of Jiaxing University | 108 | 2026-01-01 | 2025-12-16 |
| Efficacy and Safety of Transcutaneous Auricular Vagus Nerve Stimulation for Postoperative Headache Following Stent-Assisted Coiling of Unruptured Intracranial Aneurysms Transcutaneous Auricular Vagus Nerve Stimulation, Sham transcutaneous auricular vagus nerve stimulation - Unruptured Intracranial Aneurysm, Headache | Not applicable | Recruiting | Beijing Tiantan Hospital | 440 | 2025-09-30 | 2026-03-18 |
| Effects of Transcutaneous Auricular Vagus Nerve Stimulation on Symptom Severity, Sleep Quality, Central Sensitization, and Kinesiophobia in Fibromyalgia Active Transcutaneous Auricular Vagus Nerve Stimulation (TaVNS), Sham Transcutaneous Auricular Vagus Nerve Stimulation - Fibromyalgia (FM), Chronic Pain | Not applicable | Completed | Hatice Betigul Meral | 30 | 2025-08-01 | 2026-01-15 |
| Mechanisms of Transcutaneous Auricular Vagus Nerve Stimulation in Depression transcutaneous auricular vagus nerve stimulation, sham transcutaneous auricular vagus nerve stimulation - Depressive Disorder, Bipolar Disorder | Not applicable | Recruiting | Max-Planck-Institute of Psychiatry | 86 | 2025-03-18 | 2025-06-15 |
| Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for Inflammation and Depression Following SCI Active Transcutaneous Auricular Vagus Nerve Stimulation, Sham Transcutaneous Auricular Vagus Nerve Stimulation - Spinal Cord Injury, Depression | Not applicable | Unknown | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 44 | 2025-01-27 | 2025-02-07 |
| taVNS Combined With TENS on Motor Function in Stroke transcutaneous auricular vagus nerve stimulation, sham transcutaneous auricular vagus nerve stimulation, transcutaneous electrical nerve stimulation - Stroke | Not applicable | Recruiting | The Hong Kong Polytechnic University | 120 | 2025-01-01 | 2026-02-23 |
| Ameliorating Effects and Mechanisms of TaVNS on Constipation in PD Patients. active Transcutaneous auricular vagus nerve stimulation, sham Transcutaneous auricular vagus nerve stimulation - Parkinson Disease, Idiopathic, Constipation | Not applicable | Not yet recruiting | Kezhong Zhang | 30 | 2024-10-15 | 2024-10-04 |
| TaVNS Improves the Symptoms of Patients With Moderate to Severe CP/CPPS Transcutaneous Auricular Vagus Nerve Stimulation, Sham Transcutaneous Auricular Vagus Nerve Stimulation - Chronic Prostatitis | Not applicable | Recruiting | Jiani Wu | 68 | 2024-03-15 | 2025-11-28 |
| A Study on Transcutaneous Vagus Nerve Stimulation in Perioperative Period of Percutaneous Coronary Intervention transcutaneous auricular vagus nerve stimulation, sham transcutaneous auricular vagus nerve stimulation - Coronary Artery Disease, Hypertension | Not applicable | Completed | Guozhe Sun | 480 | 2023-09-12 | 2025-12-03 |
| The Efficacy and Safety of Transcutaneous Auricular Vagus Nerve Stimulation for Anxiety in PD Active Transcutaneous auricular vagus nerve stimulation, Sham Transcutaneous auricular vagus nerve stimulation - Parkinson Disease | Not applicable | Unknown | The First Affiliated Hospital with Nanjing Medical University | 30 | 2023-08-01 | 2023-07-28 |
Showing 20 of 24. Sign in to see all of them.
Depression (4) · Parkinson Disease (4) · Inflammation (3) · Anxiety Disorders (2) · Diabetes Mellitus, Type 2 (2) · Spinal Cord Injuries (2) · Agnosia (1) · Bipolar Disorder (1) · Bursitis (1) · Cerebral Palsy (1) · Chronic Pain (1) · Cognitive Dysfunction (1) · Combat Disorders (1) · Complex Regional Pain Syndromes (1) · Consciousness Disorders (1)
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (3) · Beijing Tiantan Hospital (2) · Burrell College of Health Sciences (2) · The First Affiliated Hospital with Nanjing Medical University (2) · Affiliated Hospital of Jiaxing University (1) · Fondazione Policlinico Universitario Campus Bio-Medico (1) · Guozhe Sun (1) · Hatice Betigul Meral (1) · Istanbul Gelisim University (1) · Jiani Wu (1) · Kezhong Zhang (1) · Liv Hospital Vadistanbul (1) · Max-Planck-Institute of Psychiatry (1) · Medical University of South Carolina (1) · Muhsin Doran (1)
China (5) · United States (5) · Canada (3) · Turkey (Türkiye) (3) · Germany (1) · Hong Kong (1) · Italy (1)
Harald M Stauss, MD, PhD (2) · Kezhong Zhang (2) · Muhsin Doran (2) · David J Allison, PhD. (1) · Massimo Marano, MD, PhD (1) · Peter Falkai, MD (1) · Shamay Ng, Professor (1) · Yingxian Sun (1)
PMID 32190684, PMID 36438970, PMID 40428830, PMID 42264522
R41HD104409 (1)