8 completed. 8 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 8 | Completed 8 |
| Phase 2 | 1 | Completed 1 |
Follow Pyrimethamine: new trials by email Literature Review of Pyrimethamine trials Research Report on Pyrimethamine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prevention of Congenital Toxoplasmosis With Pyrimethamine + Sulfadiazine Versus Spiramycine During Pregnancy Pyrimethamine/Sulfadiazine, Spiramycine - Congenital Toxoplasmosis | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 149 | 2010-11-01 | 2016-09-29 |
| A Randomised Trial of Artesunate-sulfamethoxypyrazine/Pyrimethamine Versus Praziquantel for the Treatment of S. Mansoni Artesunate+Sulfamethoxypyrazine/pyrimethamine, Praziquantel - Schistosoma Mansoni | Phase 3 | Completed | Kenya Medical Research Institute | 212 | 2009-10-01 | 2010-01-22 |
| A Comparative Study of Artekin With Standard Malarial Treatment Regimes in Afghanistan Dihydroartemisinin + Piperaquine (Artekin), artesunate-sulphadoxin/pyrimethamine, chloroquine - Uncomplicated Falciparum Malaria, Vivax Malaria | Phase 3 | Completed | University of Oxford | 1086 | 2007-07-01 | 2018-05-09 |
| Antimalarial Treatments for Clearing Low Density P. Falciparum and Its Impact on Malaria Transmission Sulfadoxine / Pyrimethamine (SP) plus artesunate (AS), placebo tablet similar to active drug in shape and size - Plasmodium Falciparum, Asymptomatic Parataemia | Phase 3 | Completed | Tropical Medicine Research Institute | 2005-08-01 | 2008-03-28 | |
| Longitudinal Antimalarial Combinations in Uganda Amodiaquine+Artesunate, Amodiaquine+Sulfadoxine/Pyrimethamine, Artemether+Lumefantrine - Malaria | Phase 3 | Completed | University of California, San Francisco | 601 | 2004-11-01 | 2020-06-09 |
| Anti-Malarial Drug Resistance in Cameroon Amodiaquine and Sulphadoxine/Pyrimethamine - Malaria | Phase 2 / Phase 3 | Completed | London School of Hygiene and Tropical Medicine | 755 | 2003-08-01 | 2017-01-12 |
| Effect of Specific Anti-Toxoplasmatic Add-on Medication in Toxoplasma Gondii Seropositive Individuals With Schizophrenia or Major Depression daraprim, pyrimethamine, folinic acid - Schizophrenia, Major Depression | Phase 3 | Completed | Zentrum für Integrative Psychiatrie | 40 | 2002-01-01 | 2006-05-22 |
| A Controlled Comparative Trial of Sulfamethoxazole-Trimethoprim Versus Aerosolized Pentamidine for Secondary Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients Receiving Azidothymidine (AZT) Pentamidine isethionate, Pyrimethamine, Sulfamethoxazole/Trimethoprim - Pneumonia, Pneumocystis Carinii, HIV Infections | Phase 3 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 322 | 2021-11-03 |
Malaria (2) · Malaria, Falciparum (2) · AIDS-Related Opportunistic Infections (1) · Acquired Immunodeficiency Syndrome (1) · Depression (1) · Depressive Disorder, Major (1) · HIV Infections (1) · Malaria, Vivax (1) · Mood Disorders (1) · Pneumonia, Pneumocystis (1) · Psychotic Disorders (1) · Respiratory Aspiration (1) · Schistosomiasis (1) · Schizophrenia (1) · Toxoplasmosis, Congenital (1)
Assistance Publique - Hôpitaux de Paris (1) · Kenya Medical Research Institute (1) · London School of Hygiene and Tropical Medicine (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Tropical Medicine Research Institute (1) · University of California, San Francisco (1) · University of Oxford (1) · Zentrum für Integrative Psychiatrie (1)
Afghanistan (1) · France (1) · Kenya (1) · Sudan (1) · Uganda (1) · United States (1)
Badria B El Sayed, PhD,MSc,BSc (1) · Dunja Hinze-Selch, MD (1) · Ghulam R Awab, MD (1) · Hardy WD (1) · Holzman R (1) · Laurent Mandelbrot, MD (1) · Pauline N Mwinzi, PhD (1) · Wilfred Mbacham, ScD (1)
PMID 16551365, PMID 17239256, PMID 17519410, PMID 18522503, PMID 18547415, PMID 18547416, PMID 19199542, PMID 20409302, PMID 20689585, PMID 20705516, PMID 26917051, PMID 34585740