5 completed, 4 terminated, 2 recruiting, 1 active not recruiting. 6 Phase 2, 4 Phase 1, 2 Early Phase 1, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 2, Recruiting 2, Suspended 1, Terminated 1 |
| Phase 1 | 4 | Completed 2, Suspended 1, Terminated 1 |
| Early Phase 1 | 2 | Active not recruiting 1, Completed 1 |
| Phase 4 | 2 | Terminated 2 |
Follow propranolol CR: new trials by email Literature Review of propranolol CR trials Research Report on propranolol CR
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Propranolol in Combination With Pembrolizumab and Standard Chemotherapy for the Treatment of Unresectable Locally Advanced or Metastatic Esophageal or Gastroesophageal Junction Adenocarcinoma Biopsy, Biospecimen Collection, Computed Tomography - Clinical Stage II Esophageal Adenocarcinoma AJCC v8, Clinical Stage III Esophageal Adenocarcinoma AJCC v8 | Phase 2 | Recruiting | Roswell Park Cancer Institute | 40 | 2023-03-07 | 2025-12-16 |
| Propranolol for Protracted Labor Propranolol - Labour;Obstructed, Labor Dystocia | Phase 1 | Completed | Christiana Care Health Services | 80 | 2021-07-27 | 2022-07-28 |
| Propranolol With Chemotherapy or Chemoradiation for Esophageal Adenocarcinoma Carboplatin, 3 Dimensional Conformal Radiation Therapy, Propranolol - Esophageal Adenocarcinoma | Phase 2 | Recruiting | Roswell Park Cancer Institute | 106 | 2021-04-01 | 2026-10-22 |
| Propranolol Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery Laboratory Biomarker Analysis, Propranolol Hydrochloride, Questionnaire Administration - Prostate Carcinoma | Phase 2 | Terminated | Wake Forest University Health Sciences | 46 | 2019-01-15 | 2026-08-03 |
| Propranolol Hydrochloride and Pembrolizumab in Treating Patients With Stage IIIC-IV Melanoma That Cannot Be Removed by Surgery Laboratory Biomarker Analysis, Pembrolizumab, Propranolol Hydrochloride - Stage IIIC Cutaneous Melanoma AJCC v7, Stage IV Cutaneous Melanoma AJCC v6 and v7 | Phase 1 / Phase 2 | Suspended | Roswell Park Cancer Institute | 47 | 2018-01-31 | 2026-07-15 |
| Brief Intervention to Reduce Fear of Public Speaking propranolol, Placebo - Social Anxiety Disorder | Phase 4 | Terminated | New York State Psychiatric Institute | 6 | 2016-06-01 | 2023-06-07 |
| Study of Propranolol to Decrease Gene Expression of Stress-Mediated Beta-Adrenergic Pathways in HCT Recipients Propranolol - Multiple Myeloma | Phase 2 | Completed | Medical College of Wisconsin | 25 | 2015-07-17 | 2021-06-07 |
| Modafinil and Cognitive Function in POTS Placebo, Modafinil, Propranolol - Postural Tachycardia Syndrome | Early Phase 1 | Active not recruiting | Vanderbilt University Medical Center | 20 | 2014-10-01 | 2026-01-15 |
| Study of Propranolol in Newly Diagnosed Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy Propranolol, DOT imaging, Paclitaxel - Locally Advanced Malignant Neoplasm, Breast Cancer | Phase 2 | Completed | Columbia University | 10 | 2012-10-01 | 2021-09-10 |
| Perioperative Propranolol in Patients With Post Traumatic Stress Disorder (PTSD) Propranolol Hydrochloride, Placebo - Post-traumatic Stress Disorder | Phase 4 | Terminated | University of California, San Francisco | 59 | 2012-05-01 | 2026-07-02 |
| Propranolol Hydrochloride and Chemotherapy in Treating Patients With Ovarian, Primary Peritoneal, or Fallopian Tube Cancer Chemotherapy, Propranolol Hydrochloride, Quality-of-Life Assessment - Fallopian Tube Clear Cell Adenocarcinoma, Fallopian Tube Endometrioid Adenocarcinoma | Early Phase 1 | Completed | M.D. Anderson Cancer Center | 32 | 2012-03-09 | 2019-08-29 |
| Propanolol and Red Cell Adhesion Non-asthmatic Children Sickle Cell Disease propranolol - Sickle Cell Disease | Phase 1 | Terminated | University of Miami | 9 | 2010-06-01 | 2017-06-08 |
| Pharmacokinetic Study in Patients With Chronic Kidney Disease and Healthy Volunteers Propranolol, Losartan, Eprosartan - Kidney Disease | Phase 1 | Completed | University of California, San Francisco | 24 | 2010-03-01 | 2013-05-30 |
Adenocarcinoma Of Esophagus (2) · Anemia, Sickle Cell (1) · Autonomic Nervous System Diseases (1) · Breast Neoplasms (1) · Cardiovascular Diseases (1) · Dystocia (1) · Fallopian Tube Neoplasms (1) · Kidney Diseases (1) · Melanoma (1) · Multiple Myeloma (1) · Nervous System Diseases (1) · Neurobehavioral Manifestations (1) · Neurologic Manifestations (1) · Orthostatic Intolerance (1) · Phobia, Social (1)
Roswell Park Cancer Institute (3) · University of California, San Francisco (2) · Christiana Care Health Services (1) · Columbia University (1) · M.D. Anderson Cancer Center (1) · Medical College of Wisconsin (1) · New York State Psychiatric Institute (1) · University of Miami (1) · Vanderbilt University Medical Center (1) · Wake Forest University Health Sciences (1)
United States (13)
Anurag Singh, MD (1) · Ashok Hemal (1) · Franklin Schneier, MD (1) · Helen B Gomez, MD (1) · Italo Biaggioni, M.D. (1) · Jennifer Knight, MD (1) · Kannan Thanikachalam (1) · Kevin M. Kalinsky, MD, MS (1) · Leslie Z Benet, PhD (1) · Lois M Ramondetta (1) · Lynda Frassetto, MD (1) · Marek Brzezinski, M.D., Ph.D. (1) · Ofelia A Alvarez, MD (1) · Shipra Gandhi, MD (1)
PMID 18550886, PMID 19840322, PMID 20117846, PMID 20644039, PMID 20732454, PMID 20797926, PMID 20936416, PMID 29793446, PMID 32027744
5UL1TR000445-07 (1), P30CA012197 (1), P30CA016672 (1), UL1TR000040 (1)