307 completed, 48 unknown, 46 terminated, 19 recruiting. 154 Phase 2, 124 Not applicable, 98 Phase 3, 74 Phase 1, 36 Phase 4.
Follow Placebo Comparator: new trials by email Literature Review of Placebo Comparator trials Research Report on Placebo Comparator
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of SAT-3247 to Evaluate the Safety, Tolerability, and Efficacy in Participants With Facioscapulohumeral Muscular Dystrophy (FSHD) forazapadin, Placebo Comparator - Facioscapulohumeral Muscular Dystrophy (FSHD) | Phase 2 | Not yet recruiting | Satellos Bioscience, Inc. | 51 | 2026-12-15 | 2026-10-13 |
| Oral VK2735 for Weight Management Phase 3 (SUNRISE 1) VK2735, Placebo comparator - Weight Loss | Phase 3 | Not yet recruiting | Viking Therapeutics, Inc. | 560 | 2026-11-01 | 2026-10-16 |
| Oral VK2735 for Weight Management in Adults With Type 2 Diabetes Mellitus Phase 3 (SUNRISE 2) VK2735 Oral, Placebo Comparator - Weight Loss | Phase 3 | Not yet recruiting | Viking Therapeutics, Inc. | 560 | 2026-11-01 | 2026-10-16 |
| A Phase 2b/3 Clinical Study Evaluating T3D-959 in Mild-to-Moderate Alzheimer's Disease Subjects T3D-959, Placebo Comparator - Alzheimer's Disease | Phase 2 / Phase 3 | Not yet recruiting | T3D Therapeutics, Inc. | 376 | 2026-10-26 | 2025-05-09 |
| PROMOTE: Effects of 5-HT4 Agonism on Cognition and Sleep in Peopl With Low Mood Prucalopride, Placebo Comparator - Low Mood, Depression - Major Depressive Disorder | Not applicable | Not yet recruiting | University of Oxford | 60 | 2026-10-01 | 2026-10-06 |
| Study to Evaluate Xtressé Gummy Supplement in Men With Androgenic Alopecia Xtressé Hair Growth Gummies, Placebo Comparator - Androgenic Alopecia, Hair Loss/Baldness | Not applicable | Not yet recruiting | Restore Biologics Holdings, Inc. dba Xtressé | 48 | 2026-09-29 | 2026-08-17 |
| Beta-Alanine Effects on Neuromuscular and Cardiovascular Performance in Female Rugby Players Placebo Comparator, Beta-Alanine - Beta Alanine Supplementation, Placebo - Control | Not applicable | Enrolling by invitation | Universidad Pontificia Comillas | 30 | 2026-09-01 | 2026-09-09 |
| Testing Two Doses of Nebulized Ketamine for Postoperative Sore Throat Placebo Comparator, Ketamine 50 MG/ML, Ketamine 25 mg - Postoperative Sore Throat | Not applicable | Completed | Aswan University Hospital | 195 | 2026-08-15 | 2026-09-02 |
| Evaluating Safety and Efficacy of VV119 in Acute Schizophrenia Adults VV119 2mg, VV119 4mg, VV119 6mg - Schizophrenia | Phase 2 | Not yet recruiting | Vigonvita Life Sciences | 500 | 2026-07-31 | 2026-07-15 |
| The BALANCE Study - Improving Glucose Control Through Prebiotic Gut Health Drink in Postmenopausal Women ió everyday (a prebiotic- enriched gut health drink containing inulin), Placebo Comparator - Menopause | Not applicable | Completed | University of Roehampton | 30 | 2026-06-10 | 2026-10-20 |
| Can Aspirin Reduce the Risk of HCC in Cirrhosis: The AspiRe HCC Trial Low-dose aspirin, Placebo Comparator - Liver Cirrhosis | Phase 3 | Not yet recruiting | Curtin University | 890 | 2026-06-01 | 2026-04-14 |
| The Role of Estradiol and Progesterone on Appetite Regulation and Energy Balance Placebo Comparator, Estradiol Only, Progesterone Only - Energy Balance, Physiology - Regulation of Appetite and Food Intake | Not applicable | Recruiting | Wilfrid Laurier University | 60 | 2026-06-01 | 2026-06-02 |
| Effects of Hemp-Derived Cannabinoids on Menopause Symptoms Hemp-derived cannabinoids, Placebo - Menopause, Perimenopause | Phase 2 | Recruiting | Washington State University | 104 | 2026-02-11 | 2026-03-10 |
| A Controlled Study to Evaluate the Effects of a Topical Cream on Symptoms of Arthritis, Joint, and Muscle Pain Intervention (Saje Pain Release Joint & Arthritis Cream), Placebo Comparator - Arthritis, Joint Pain | Not applicable | Completed | Saie Beauty | 80 | 2026-02-01 | 2026-08-17 |
| Effect of Plant vs Animal Protein Supplementation on Body Composition in Youth Soccer Players Plant-Based Protein Supplement, Animal-Based Protein Supplement (Whey), Placebo - Athletic Performance Enhancement, Body Composition Optimization | Not applicable | Completed | Antonio Molina Lopez | 25 | 2026-01-17 | 2026-05-06 |
| Evaluating the Safety, Tolerability, and Efficacy of GRF312 5% in Participants With Dry Eye Disease (DED). GRF312 5%, Placebo Comparator - Dry Eye Disease | Phase 2 | Completed | Instituto Grifols, S.A. | 103 | 2025-11-03 | 2026-06-16 |
| Plant Protein With Ashwagandha-Rhodiola for Sleep Quality Plant Protein Supplement, Rhodiola rosea Extract, Ashwagandha KSM-66 - Sleep Quality, Sleep Disorders | Not applicable | Completed | Universidad Pablo de Olavide | 100 | 2025-11-01 | 2026-03-10 |
| This is a Phase 1, Randomized, Single-blind, Placebo-controlled Study to Assess the Safety, Pharmacokinetics (PK), and Pharmacodynamics (PD) of BEAM-103 in Healthy Subjects BEAM-103, Placebo Comparator - Healthy Subjects, Healthy Participant Study | Phase 1 | Recruiting | Beam Therapeutics Inc. | 30 | 2025-10-27 | 2025-12-26 |
| Impact of Haskap Berries on Recovery From High Intensity Resistance Training Haskap berry smoothie, Placebo Comparator - Inflammation, Oxidative Stress | Not applicable | Recruiting | Montana State University | 30 | 2025-10-21 | 2026-01-21 |
| Hydrogen-Rich Water and Resting Metabolism in Young Adults Molecular Hydrogen, Placebo Comparator - Healthy Subjects or Volunteers | Not applicable | Not yet recruiting | University of Novi Sad | 24 | 2025-09-01 | 2025-08-01 |
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