13 completed, 6 recruiting, 3 not yet recruiting, 2 terminated. 23 Not applicable, 4 Phase 3, 2 Phase 2.
Follow PE: new trials by email Literature Review of PE trials Research Report on PE
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Web-Based Insomnia Treatment for Spousal Dementia Caregivers (SHUTi-DC) SHUTi-DC, PE - Insomnia | Not applicable | Not yet recruiting | University of Missouri-Columbia | 80 | 2027-01-01 | 2026-09-23 |
| PACE Versus PE for CPTSD (PACE Trial) PACE, PE - Complex Posttraumatic Stress Disorder | Not applicable | Not yet recruiting | Sofie Folke | 228 | 2026-10-01 | 2026-09-09 |
| Adaptive Decision-making And Personalized Treatment for PTSD (ADAPT-PTSD) Modular Cognitive Processing Therapy, Modular Prolonged Exposure Therapy, Step Down Treatment - Posttraumatic Stress Disorder, PTSD | Not applicable | Recruiting | The University of Texas Health Science Center at San Antonio | 302 | 2025-12-12 | 2025-12-19 |
| Evaluating Evidenced Based Options for PTSD Treatment Cognitive Processing Therapy, Prolonged Exposure, Skills Training for Affective and Interpersonal Regulation - PTSD - Post Traumatic Stress Disorder | Not applicable | Recruiting | Rush University Medical Center | 400 | 2025-10-06 | 2026-10-28 |
| Shared Decision Making in PTSD Treatment Prolonged Exposure Therapy, Cognitive Processing Therapy, Written Exposure Therapy - Post Traumatic Stress Disorder PTSD | Not applicable | Recruiting | The University of Texas Health Science Center at San Antonio | 200 | 2025-05-09 | 2026-08-19 |
| Multicomponent vs Pilates on Mass, Strength, and Physical Performance in Older Adults ME, PE - Muscle Mass, Muscle Strength | Not applicable | Not yet recruiting | Universidade Estadual do Norte do Parana | 100 | 2025-05-01 | 2024-12-13 |
| MDMA-assisted Massed Prolonged Exposure for PTSD 3,4 Methylenedioxymethamphetamine, Prolonged Exposure - Post-Traumatic Stress Disorder | Phase 3 | Active not recruiting | Healing Breakthrough | 20 | 2024-10-25 | 2026-08-26 |
| Evaluating Treatments for Suicidal Veterans With PTSD Dialectical Behavior Therapy, Dialectical Behavior Therapy Prolonged Exposure protocol, Prolonged Exposure therapy - Self-directed Violence, Post-traumatic Stress Disorder (PTSD) | Not applicable | Recruiting | VA Office of Research and Development | 125 | 2024-07-08 | 2026-07-16 |
| Effectiveness of Trauma Therapy Using Prolonged Exposure for Patients With PTSD and a Comorbid Psychotic Disorder Prolonged Exposure - Post Traumatic Stress Disorder, PTSD | Not applicable | Recruiting | Medicalschool Hamburg | 56 | 2023-05-15 | 2023-09-21 |
| A Study With Imlifidase in Anti-GBM Disease Imlifidase, Plasma exchange (PLEX), Cyclophosphamide (CYC) - Anti-Glomerular Basement Membrane Disease, Anti-Glomerular Basement Membrane Antibody Disease | Phase 3 | Terminated | Hansa Biopharma AB | 50 | 2022-12-22 | 2026-03-04 |
| Efficacy and Safety of ALSS Treatment for ICIs-LF in Patients With HCC DPMAS+LPE, PE, Comprehensive internal medical treatment - Immune-Mediated Hepatitis, Liver Failure | Not applicable | Recruiting | Third Affiliated Hospital, Sun Yat-Sen University | 60 | 2022-08-12 | 2024-11-29 |
| Comparison Between Pelvic Muscle Training and Pilates Exercises for UI in Postmenopausal Women PFMT, PE - Urinary Incontinence | Not applicable | Completed | Universidade Estadual do Norte do Parana | 40 | 2022-06-01 | 2023-05-09 |
| TDCS-Augmented Prolonged Exposure Therapy Transcranial Direct Current Stimulation (tDCS), Prolonged Exposure Therapy - Posttraumatic Stress Disorder, PTSD | Not applicable | Withdrawn | Medical University of South Carolina | 2021-10-01 | 2024-10-24 | |
| rATG Versus rATG Combined With Intravenous Immunoglobulin (IVIG) Induction Immunosuppression in HLA Incompatible Transplantation (INHIBIT) Privigen, Thymoglobulin, Plasma Exchange - Kidney Transplantation | Phase 3 | Completed | Institute for Clinical and Experimental Medicine | 17 | 2020-07-27 | 2024-08-15 |
| Cannabidiol and Prolonged Exposure Prolonged Exposure, Cannabidiol, placebo - PTSD | Phase 2 | Completed | VA Office of Research and Development | 136 | 2019-10-01 | 2026-10-28 |
| Evaluating the Feasibility of RESCUE: An Adjunctive HAI-Based Intervention for Veterans With PTSD RESCUE, Prolonged Exposure - PTSD | Not applicable | Completed | Charleston Research Institute | 57 | 2016-09-27 | 2020-01-22 |
| Patient Education and Basic Body Awareness Therapy in Hip Osteoarthritis: a Randomized Controlled Trial Patient Education and Basic Body Awareness Therapy, Patient Education - Hip Osteoarthritis | Not applicable | Completed | University of Bergen | 101 | 2015-10-01 | 2019-10-08 |
| Physical Exercise Program for Family Caregivers of Dependent Patients PE, Usual Care - Caregiver, Physical Activity | Not applicable | Completed | Fundacion para la Investigacion y Formacion en Ciencias de la Salud | 68 | 2015-09-14 | 2018-09-18 |
| Innovative Delivery of Evidence Based Psychotherapy to Women With Military Sexual Trauma PE - PTSD, Stress Disorders, Post - Traumatic | Not applicable | Completed | Medical University of South Carolina | 136 | 2014-08-01 | 2019-12-24 |
| Improving Memory for Sleep Treatment Content With Text Messages PUSH text messages, PULL text messages, TranS-C - Sleep Wake Disorders | Not applicable | Completed | University of California, Berkeley | 176 | 2013-10-01 | 2019-10-29 |
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Stress Disorders, Post-Traumatic (14) · Combat Disorders (7) · Anxiety Disorders (3) · Depression (2) · Motor Activity (2) · Sleep Initiation and Maintenance Disorders (2) · Sleep Wake Disorders (2) · Stress Disorders, Traumatic (2) · Wounds and Injuries (2) · Anti-Glomerular Basement Membrane Disease (1) · Attention Deficit Disorder with Hyperactivity (1) · Carcinoma, Hepatocellular (1) · Liver Failure (1) · Mental Disorders (1) · Neoplasms (1)
Medical University of South Carolina (2) · National Center for Telehealth and Technology (2) · The University of Texas Health Science Center at San Antonio (2) · Universidade Estadual do Norte do Parana (2) · VA Office of Research and Development (2) · Charleston Research Institute (1) · Emory University (1) · Fundacion para la Investigacion y Formacion en Ciencias de la Salud (1) · Hansa Biopharma AB (1) · Healing Breakthrough (1) · Institute for Clinical and Experimental Medicine (1) · Medicalschool Hamburg (1) · Modum Bad (1) · Philipps University Marburg (1) · Rush University Medical Center (1)
United States (17) · Germany (3) · Brazil (2) · Czechia (2) · Denmark (2) · Norway (2) · Spain (2) · Austria (1) · Belgium (1) · China (1) · France (1) · Ireland (1) · Italy (1) · Netherlands (1) · Sweden (1)
Greg Reger, PhD (2) · Gregory A Gahm, PhD (2) · Adam R. Cobb, Ph.D. (1) · Alan L Peterson, PhD (1) · Allison G Harvey, PhD (1) · Anouk Grubaugh, PhD (1) · Asle Hoffart, PhD (1) · Barbara O Rothbaum, PhD, ABPP (1) · Bethany C. Wangelin, Ph.D. (1) · Brian Martis, MD (1) · Catherine R Ayers, PhD (1) · David Cognetti, MD (1) · Federico Montero Cuadrado (1)
PMID 10533438, PMID 12428777, PMID 15229303, PMID 16507803, PMID 17353495, PMID 17723027, PMID 18052556, PMID 25505396, PMID 31246050, PMID 31872563, PMID 31880749, PMID 31881993, PMID 33472513, PMID 34391978, PMID 36061275, PMID 38206341, PMID 39640621, PMID 39704322, PMID 40458542, PMID 42313651, PMID 42603614, PMID 42780432, PMID 7492257, PMID 9489273
P30AG086642 (1)