Paracetamol: Clinical Trials

319 trials of Paracetamol, newest first

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219 completed, 53 unknown, 17 terminated, 8 recruiting. 108 Phase 4, 80 Not applicable, 50 Phase 3, 44 Phase 2, 37 Phase 1.

By phase and status

PhaseTrialsStatus
Phase 4108Completed 78, Unknown 16, Terminated 8, Recruiting 3, Not yet recruiting 2, Active not recruiting 1
Not applicable80Completed 50, Unknown 17, Not yet recruiting 4, Recruiting 3, Withdrawn 3, Terminated 2, Active not recruiting 1
Phase 350Completed 33, Unknown 9, Terminated 3, Withdrawn 3, Active not recruiting 1, Suspended 1
Phase 244Completed 29, Unknown 8, Terminated 3, Active not recruiting 2, Suspended 1, Withdrawn 1
Phase 137Completed 24, Unknown 6, Active not recruiting 2, Terminated 2, Not yet recruiting 1, Recruiting 1, Suspended 1
Early Phase 14Completed 3, Unknown 1

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Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Intravenous Paracetamol Versus Magnesium Sulfate for Control of Shivering Following Spinal Anesthesia in Cesarean Section
Paracetamol, Magnesium Sulfate - Shivering, Post-Spinal Shivering
Phase 4Not yet recruitingAssiut University902026-11-012026-10-02
Comparison of Two Postoperative Care Strategies After Breast Surgery
Patient Education, Paracetamol, Dexketoprofen - Postoperative Pain, Pain Management
Not applicableRecruitingMoumtzidou Maria Aikaterini1082026-10-192026-10-20
Effect of Nonsteroidal Anti-Inflammatory Drug Restriction on the Efficacy of Platelet-Rich Plasma in Knee Osteoarthritis
Leukocyte-Rich Platelet-Rich Plasma, ibuprofen, Acetaminophen - Osteoarthritis, Knee
Not applicableNot yet recruitingFederal University of São Paulo902026-10-012026-08-14
A Research Study Looking Into How a High Dose of s.c. Semaglutide Works With Emptying of the Stomach in People With Excess Body Weight
Semaglutide, Placebo semaglutide, Paracetamol - Obesity, Overweight
Phase 1Not yet recruitingNovo Nordisk A/S602026-09-252026-09-29
Epidural Analgesia Versus Opioid-sparing Analgesia for Open Ventral Hernia Repair With Transversus Abdominis Release
Bupivicaine, Fentanyl, Thoracic epidural analgesia - Ventral Hernia, Ventral Hernia Repair
Phase 4RecruitingNorthwestern University402026-09-252026-10-07
Post-Vasectomy Pain Study
Acetaminophen, ibuprofen, oxycodone - Vasectomy, NSAIDs
Phase 1RecruitingColumbia University2002026-09-102026-09-24
Holistic Healing for Knee Osteoarthritis
Trayodashang Guggulu, Ashwagandha Churna, Janubasti - Knee Osteoarthritis (Knee OA)
Not applicableNot yet recruitingAll India Institute of Medical Sciences, Jodhpur3002026-09-012026-08-27
Does Paracetamol Influence the Release of Gut Hormones, Glucose Absorption and Glycemia?
Paracetamol, Placebo - Healthy Young Adults, Physiology
Not applicableRecruitingUniversity of Copenhagen122026-06-012026-09-15
A Study to Learn About the Effect of Study Medicine Called PF-08653944 on How Quickly the Stomach Empties Its Content in Healthy Adults With Overweight or Obesity
PF-08653944, Acetaminophen - Obesity, Overweight and/or Obesity
Phase 1Active not recruitingPfizer222026-03-312026-07-09
Ultrasound Guided Pecs Block and Ketamine Infusion for Preventing Chronic Pain in Patients Undergoing Breast Cancer Surgery
Ketamine, Pecs block, Nalbuphine - Breast Cancer, Pain, Chronic
Not applicableNot yet recruitingAga Khan University1202026-03-162026-02-19
Antipyretic Therapy With and Without Cold Sponging
Paracetamol, Paracetamol+Cold Sponging - Fever
Not applicableNot yet recruitingMuhammad Aamir Latif2102026-03-012026-02-23
Continous Infusion of Nefopam for Patients Undergoing Pancreatoduodenectomy
Nefopam 120mg/day infusion, Lidocaine Infusion, Peridural - Pancreatoduodenectomy, Pain Management
Phase 4RecruitingIuliu Hatieganu University of Medicine and Pharmacy932026-03-012026-03-24
Elevation of Effect of Common Analgesic on Pulp Sensibility Tet
Paracetamol, Ibuprofen - Pulpal Condition
Not applicableCompletedPakistan Institute of Medical Sciences1842026-02-012026-06-01
Comparison Between 2 Techniques for Lumbar-ESPB
spinal anesthesia, superficial erector spinal plane block (ESPB), deep (inter laminar) erector spinal plane block (ESPB) - Hip Surgery
Not applicableCompletedPapa Giovanni XXIII Hospital442025-10-062026-08-25
Evaluating Premedication Regimens (Methylprednisolone vs Dexamethasone-based) for the Prevention of Systemic and Injection Site Reactions to Motixafortide in Patients With Multiple Myeloma Undergoing Stem Cell Mobilization, PARADE Trial
Acetaminophen, Biospecimen Collection, Dexamethasone - Multiple Myeloma
Phase 4RecruitingEmory University942025-09-242026-07-23
Lidocaine, Paracetamol, and Dexmedetomidine for Rocuronium Injection Pain
Lidocaine %2 ampoule, Dexmedetomidine, paracetamol - Propofol Injection Pain, Rocuronium Injection Pain
Phase 4Not yet recruitingBaskent University1702025-09-012025-09-11
Pain Control After Open Radical Nephrectomy: Thoracic Paravertebral Block Versus External Oblique Intercostal Block
Bupivacaine, morphine, paracetamol - Nephrectomy, Pain Scores
Not applicableCompletedHacettepe University982025-08-012026-03-17
A Study of BGM0504 in Overweight or Obese Participants
Paracetamol, Metformin Hydrochloride, Warfarin - Overweight or Obese
Phase 1CompletedBrightGene Bio-Medical Technology Co., Ltd.282025-03-252026-10-13
Comparison Paravertebral and Serratus Anterior Plane Block in Video-assisted Thoracoscopic Surgery.
Bupivacaine, Morphine, Paracetamol - Lung Cancer (NSCLC), Lung Adenocarcinoma
Not applicableActive not recruitingHacettepe University1222024-12-012025-06-04
Safety and Immunogenicity of an Investigational Pentavalent Meningococcal ABCYW Vaccine Against Meningococcal Disease in Children, Toddlers, and Infants
Pentavalent Meningococcal ABCYW vaccine, MenACYW conjugate vaccine, Meningococcal group B vaccine - Meningococcal Immunization, Healthy Volunteers
Phase 1 / Phase 2Active not recruitingSanofi Pasteur, a Sanofi Company7502024-11-052026-01-20

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Conditions studied

Pain, Postoperative (52)  ·  Pain (38)  ·  Agnosia (34)  ·  Emergencies (13)  ·  Fever (13)  ·  Acute Pain (12)  ·  Ductus Arteriosus, Patent (11)  ·  Common Cold (8)  ·  Postoperative Nausea and Vomiting (7)  ·  Osteoarthritis, Knee (6)  ·  Chronic Pain (5)  ·  Malaria (5)  ·  Neuralgia (5)  ·  Renal Colic (5)  ·  Wounds and Injuries (5)

Sponsors

Pamukkale University (13)  ·  GlaxoSmithKline (11)  ·  Cairo University (8)  ·  Ain Shams University (5)  ·  Medical University of Lublin (5)  ·  University Hospital, Clermont-Ferrand (5)  ·  University of Monastir (5)  ·  Assiut University (4)  ·  Baskent University (4)  ·  Copenhagen University Hospital, Rigshospitalet (4)  ·  Inonu University (4)  ·  Rambam Health Care Campus (4)  ·  AFT Pharmaceuticals, Ltd. (3)  ·  Benha University (3)  ·  Boehringer Ingelheim (3)

Countries

Turkey (Türkiye) (32)  ·  United States (26)  ·  Egypt (21)  ·  France (19)  ·  United Kingdom (17)  ·  Denmark (14)  ·  Israel (14)  ·  Italy (12)  ·  Poland (12)  ·  Spain (12)  ·  Brazil (8)  ·  Norway (8)  ·  Netherlands (7)  ·  Switzerland (7)  ·  Germany (6)

Top investigators

Atakan Yilmaz, MD (2)  ·  Eva-Corina Caragounis, MD (2)  ·  Frank Ruschitzka, MD (2)  ·  Hans Granhed, MD PhD (2)  ·  Katherine Plewes, MD (2)  ·  Lars Arendt-Nielsen, Dr.Sci.Med. (2)  ·  Mustafa Serinken, MD (2)

Results publications

PMID 11756886, PMID 23360885, PMID 23471754, PMID 24012235, PMID 24535604, PMID 25032676, PMID 10486687, PMID 10794256, PMID 12355695, PMID 12567343, PMID 16703549, PMID 21519308, PMID 22412772, PMID 24404359, PMID 25582785, PMID 25774458, PMID 26304646, PMID 29369450, PMID 29723634, PMID 33238043, PMID 36519620, PMID 1015603, PMID 10613619, PMID 11331167, PMID 11331334, PMID 11374619, PMID 11472277, PMID 12148679, PMID 12411815, PMID 12548273, PMID 12560416, PMID 14622770, PMID 14690106, PMID 15230906, PMID 15288990, PMID 17094166, PMID 17138203, PMID 17392852, PMID 17397460, PMID 17413915, PMID 17437870, PMID 18165577, PMID 18498882, PMID 18686750, PMID 18762870, PMID 18784493, PMID 18953082, PMID 19157368, PMID 19174373, PMID 19217726

NIH funding

2016 (4), 2014 (3), 2015 (3), 2023 (2), 2008 (1), 2009 (1), 2017 (1), 2018 (1), 2019 (1), 2025 (1), P30CA023074 (1), P30CA033572 (1), P30CA138292 (1), R01NS102176 (1), U10HL098115 (1)