4 recruiting, 2 unknown, 1 withdrawn. 2 Not applicable, 2 Phase 4, 1 Early Phase 1, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Recruiting 1, Unknown 1 |
| Phase 4 | 2 | Recruiting 2 |
| Early Phase 1 | 1 | Withdrawn 1 |
| Phase 2 | 1 | Unknown 1 |
| Phase 3 | 1 | Unknown 1 |
Follow Opioid-free anesthesia: new trials by email Literature Review of Opioid-free anesthesia trials Research Report on Opioid-free anesthesia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Transition From Acute to Chronic Opioid Use and Chronic Pain Opioid-free anesthesia, Opioid-based anesthesia - Opioid Use Disorder | Early Phase 1 | Withdrawn | Jacques E. Chelly | 2026-07-01 | 2026-06-30 | |
| Opioid Free and Opioid Based Anesthesia in Elective Lumbar Spine Surgery Opioid-free Anesthesia, Erector Spinae Plane Block, Opioid based Anesthesia - Lumbar Spinal Stenosis, Lumbar Disc Herniation With Radiculopathy | Recruiting | Marmara University | 75 | 2025-12-09 | 2026-03-23 | |
| A Study to Reduce Persistent Post-mastectomy Pain Using Opioid-free Anesthesia Opioid-free anesthesia, Conventional opioid-based anesthesia - Breast Cancer, Mastectomy | Not applicable | Recruiting | Gangnam Severance Hospital | 230 | 2021-12-16 | 2025-11-21 |
| Opioid Free Anaesthesia-Analgesia Strategy on Surgical Stress and Immunomodulation in Elective VATS-Lobectomy for NSCLC Opioid-Based Anesthesia-Analgesia Strategy, Opioid-free Anesthesia-Analgesia Strategy - Systemic Inflammatory Response Syndrome, Postoperative Pain, Acute | Phase 4 | Recruiting | University of Crete | 70 | 2021-10-01 | 2021-12-29 |
| Opioid-free Anesthesia in Gynecologic Surgery Opioid-free anesthesia, Opioid-using anesthesia - Gynecologic Disease | Not applicable | Unknown | Seoul National University Bundang Hospital | 164 | 2021-02-01 | 2022-07-05 |
| Opioid Free Anesthesia-Analgesia Strategy and Surgical Stress in Elective Open Abdominal Aortic Aneurysm Repair Opioid-Based Anesthesia-Analgesia Strategy, Opioid-free Anesthesia-Analgesia Strategy - Elective Surgical Procedures, Postoperative Pain | Phase 4 | Recruiting | University of Crete | 40 | 2020-10-08 | 2026-06-16 |
| Opioid Free Anesthesia vs. Opioid Anesthesia Techniques. Opioid Anesthesia, Opioid-free Anesthesia - Analgesic Drug Dependence, Colectomy | Phase 2 / Phase 3 | Unknown | University of South Florida | 100 | 2018-12-01 | 2022-05-25 |
Pain, Postoperative (4) · Opioid-Related Disorders (2) · Breast Neoplasms (1) · Carcinoma, Non-Small-Cell Lung (1) · Chronic Pain (1) · Genital Diseases, Female (1) · Intervertebral Disc Degeneration (1) · Postoperative Nausea and Vomiting (1) · Spinal Stenosis (1) · Systemic Inflammatory Response Syndrome (1)
University of Crete (2) · Gangnam Severance Hospital (1) · Jacques E. Chelly (1) · Marmara University (1) · Seoul National University Bundang Hospital (1) · University of South Florida (1)
Greece (2) · South Korea (2) · United States (2) · Turkey (Türkiye) (1)
Enrico Camporesi, MD (1) · Jacques Chelly, MD, PhD, MBA (1) · Sung Gwe G Ahn, M.D.,Ph.D. (1) · Vasileia Nyktari, MD, PhD (1) · Vasileia Nyktari, MD,PhD (1)