16 completed, 6 unknown, 4 withdrawn, 3 not yet recruiting. 30 Not applicable, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 30 | Completed 14, Unknown 6, Withdrawn 4, Not yet recruiting 3, Active not recruiting 1, Enrolling by invitation 1, Recruiting 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 4 | 1 | Completed 1 |
Follow OMT: new trials by email Literature Review of OMT trials Research Report on OMT
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Orofacial Myofunctional Therapy and Cervical Stabilization Exercises in Patients With Axis-i Group Iia Temporomandibular Dysfunction Cervical Stabilization Exercises, Orofacial Myofunctional Therapy - Temporo-mandibular Dysfunction, Disc Displacement | Not applicable | Not yet recruiting | University of Lahore | 88 | 2026-10-01 | 2026-10-01 |
| A Prospective, Randomized Multicenter Clinical Trial of the TricValve® Transcatheter Bicaval Valve System in Subjects With Severe Tricuspid Regurgitation. TricValve System, Optimal medical therapy - Tricuspid Valve Disease, Heart Valve Diseases | Not applicable | Not yet recruiting | P+F Products + Features USA Inc. | 780 | 2026-10-01 | 2026-10-09 |
| Effects of Orofascial Myofunctional Therapy and Cervical Stabilization Exercises on Temporomandibular Dysfunction orofacial myofunctional therapy, cervical stabilization exercises - Temporomandibular Disorders (TMDs), Temporo-mandibular Dysfunction | Not applicable | Not yet recruiting | Lahore University of Biological and Applied Sciences | 80 | 2026-09-15 | 2026-09-18 |
| The Effect of Osteopathic Manipulative Techniques on Human Tear Composition Osteopathic Manipulative Treatment, Sham - No Disease or Condition is Being Directly Studied, The Focus of the Study in Healthy Volunteers | Not applicable | Enrolling by invitation | Lake Erie College of Osteopathic Medicine | 30 | 2026-09-01 | 2026-08-25 |
| Asthma and Osteopathic Manipulative Technique OMT, Light touch - Asthma | Not applicable | Withdrawn | University Hospitals Cleveland Medical Center | 2026-02-01 | 2026-04-20 | |
| Neuromuscular Electrical Stimulation in Peripheral Arterial Disease NMES, OMT - Peripheral Arterial Disease(PAD), Peripheral Arterial Disease | Not applicable | Completed | Halic University | 48 | 2025-10-01 | 2026-10-01 |
| Coronary CT-Derived FFR-Guided Strategy Versus Medical Therapy ITS plus OMT, OMT - Coronary Artery Disease, Myocardial Ischaemia | Not applicable | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 1066 | 2024-10-10 | 2026-02-02 |
| LuX-Valve Plus System for Severe or Greater Tricuspid Regurgitation Transvenous Tricuspid Valve System implantation + OMT, OMT - Tricuspid Regurgitation (TR) | Not applicable | Active not recruiting | Jenscare Scientific | 126 | 2024-10-09 | 2026-07-15 |
| Effect of PCI on Clinical Prognosis of Chronic Coronary Artery Occlusion PCI, OMT - Coronary Atheroscleroses | Recruiting | The First Affiliated Hospital with Nanjing Medical University | 258 | 2023-09-17 | 2024-12-27 | |
| Quantitative Ultrasound Biomarkers to Assess Upper Trapezius Muscles in Patients With Chronic Pain Quantitative Ultrasound, Osteopathic TART Assessment, Osteopathic Manipulation Treatment - Chronic Neck Pain | Not applicable | Unknown | Rocky Vista University, LLC | 108 | 2022-08-24 | 2022-08-25 |
| OMTrigger Inject- Treating Trigger Points: Comparing Muscle Energy Technique vs. Lidocaine Needling Technique OMT - Myofascial Pain Syndrome | Terminated | AtlantiCare Regional Medical Center | 30 | 2022-01-12 | 2025-02-03 | |
| Investigating the Efficacy of Osteopathic Manipulative Treatment on Gait Dysfunction Following Knee Surgery OMT - Knee Arthroscopy, Knee Arthroplasty | Not applicable | Completed | Midwestern University | 2 | 2021-08-30 | 2023-05-19 |
| Effects of Osteopathic Manipulative Treatment of Fascial Restrictions on Body Awareness, Mood, and Proprioception OMT - Segmental and Somatic Dysfunction of Other Regions (M99.09) | Not applicable | Completed | New York Institute of Technology | 29 | 2021-03-22 | 2022-04-29 |
| EndovaScular Versus mediCaL mAnagement of Uncomplicated Type B Intramural heMatoma Trial (ESCLAIM) Thoracic endovascular aortic repair plus optimal medical therapy, Optimal medical therapy - Intramural Hematoma | Not applicable | Unknown | Guangdong Provincial People's Hospital | 154 | 2021-03-01 | 2021-06-03 |
| Effects of Osteopathic Manipulative Treatment and Bio Electro-Magnetic Regulation Therapy on Neck Pain in Adults BEMER, OMT, Sham OMT + Sham BEMER - Neck Pain | Not applicable | Completed | Lake Erie College of Osteopathic Medicine | 44 | 2019-09-17 | 2023-11-15 |
| Osteopathic Manipulative Treatment and Migraine Headaches Osteopathic Manipulative Therapy (OMT), Standard of care - Chronic Migraine, Migraine Disorders | Not applicable | Unknown | St. Luke's Hospital, Pennsylvania | 140 | 2018-10-02 | 2021-08-03 |
| Osteopathic Manipulative Treatment Induces Functional Connectivity Changes OMT, MP - Osteopathic Manipulative Treatment | Not applicable | Completed | I.R.C.C.S. Fondazione Santa Lucia | 30 | 2017-09-30 | 2020-05-14 |
| The Effect of OMT on Functional Outcomes and Anti-inflammatory Biomarkers in Mild to Moderate Traumatic Brain Injury Osteopathic Manipulative Treatment - Vestibular Disorder, Headache | Not applicable | Completed | Michigan State University | 29 | 2017-09-18 | 2020-06-24 |
| Evaluation of Outcomes of CRT and MitraClip for Treatment of Low Ejection Fraction and Functional Mitral Regurgitation in HF MitraClip, Optimal Medical Therapy, CRT-D - Functional Mitral Regurgitation, Heart Failure | Not applicable | Withdrawn | Montreal Heart Institute | 2016-12-01 | 2020-02-27 | |
| Use of Osteopathic Principles for Nonpharmacologic, Therapeutic Interventions in Women With Polycystic Ovary Syndrome OMT, Yoga - Polycystic Ovary Syndrome | Not applicable | Completed | Diana Speelman, Ph.D. | 45 | 2016-10-01 | 2017-12-26 |
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Coronary Artery Disease (4) · Angina Pectoris (2) · Asthma (2) · Headache (2) · Heart Failure (2) · Migraine Disorders (2) · Pain (2) · Pneumonia (2) · Temporomandibular Joint Disorders (2) · Tricuspid Valve Insufficiency (2) · Angina, Stable (1) · Anxiety Disorders (1) · Atherosclerosis (1) · Brain Injuries, Traumatic (1) · Cardiovascular Diseases (1)
A.T. Still University of Health Sciences (3) · Lake Erie College of Osteopathic Medicine (2) · Abbott Medical Devices (1) · AtlantiCare Regional Medical Center (1) · Diana Speelman, Ph.D. (1) · Emanuel Amier Diekmann (1) · European Institute for Evidence Based Osteopathic Medicine (1) · Fondazione Don Carlo Gnocchi ETS (1) · Guangdong Provincial People's Hospital (1) · Halic University (1) · I.R.C.C.S. Fondazione Santa Lucia (1) · Jenscare Scientific (1) · Lahore University of Biological and Applied Sciences (1) · Larkin Community Hospital (1) · Michigan State University (1)
United States (16) · China (5) · Italy (4) · Pakistan (2) · Belgium (1) · Canada (1) · Czechia (1) · Denmark (1) · France (1) · Germany (1) · Hungary (1) · Netherlands (1) · Poland (1) · Serbia (1) · Sweden (1)
Abby Rhoads, DO (1) · Amy Suessle, DO (1) · Anita Asgar, MD (1) · Bernard De Bruyne, MD (1) · Brendan S Kelly, DO (1) · Bruce Benjamin, Ph.D. (1) · Charles E. Henley, D.O., MPH (1) · David Duriancik, Ph.D. (1) · David Stuckey, DO (1) · Diana Speelman, Ph.D. (1) · Donald R Noll, D.O., FACOI (1) · Douglas Ivins, M.D. (1) · Emanuel Diekmann, DO (1) · Frances Wen, Ph.D. (1) · Francesco Cerritelli, MS, DO (1)
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