10 completed, 3 terminated, 1 withdrawn. 14 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 14 | Completed 10, Terminated 3, Withdrawn 1 |
| Phase 2 | 2 | Completed 2 |
Follow Milnacipran: new trials by email Literature Review of Milnacipran trials Research Report on Milnacipran
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of the Initial Prescription of Ketamine and Milnacipran in Depression in Patients With a Progressive Disease Ketamine, Milnacipran, Placebo - Depression | Phase 2 / Phase 3 | Completed | University Hospital, Lille | 42 | 2016-09-08 | 2025-12-16 |
| Milnacipran and Neurocognition, Pain and Fatigue in Fibromyalgia : A 13-week Randomized, Placebo Controlled Cross Over Trial Milnacipran, Placebo - Fibromyalgia, Neurocognition | Phase 3 | Completed | Duke University | 26 | 2011-07-01 | 2023-10-26 |
| A Placebo Controlled, Randomized, Double Blind Trial of Milnacipran for the Treatment of Idiopathic Neuropathy Pain Milnacipran, Placebo - Idiopathic Peripheral Neuropathy | Phase 3 | Terminated | Columbia University | 6 | 2011-04-05 | 2020-09-03 |
| Efficacy and Safety of Milnacipran in the Treatment of Fibromyalgia in an Elderly Population Savella - Fibromyalgia | Phase 3 | Terminated | Banner Health | 20 | 2011-03-01 | 2011-08-17 |
| Savella in Treatment for Provoked Vestibulodynia Milnacipran - Vestibulodynia, Vulvodynia | Phase 3 | Completed | University of Tennessee | 31 | 2010-10-01 | 2018-06-11 |
| Pain Assessment and Quality of Life in Back Pain Patients: Role of Milnacipran Savella - Back Pain | Phase 3 | Withdrawn | Brigham and Women's Hospital | 2010-08-01 | 2017-01-12 | |
| The Effect of Milnacipran in Patients With Fibromyalgia Milnacipran, Placebo - Fibromyalgia | Phase 2 / Phase 3 | Completed | Beth Israel Medical Center | 37 | 2010-03-01 | 2016-06-30 |
| Effect of Milnacipran on Pain Processing and Functional Magnetic Resonance Imaging (fMRI) Activation Patterns in Patients With Fibromyalgia Milnacipran, Placebo - Fibromyalgia | Phase 3 | Terminated | Forest Laboratories | 2 | 2008-11-01 | 2010-07-01 |
| A Study Of Milnacipran In Patients With Fibromyalgia: Effects On 24 Hour Ambulatory Blood Pressure Monitoring Milnacipran hydrochloride, Placebo - Fibromyalgia | Phase 3 | Completed | Forest Laboratories | 321 | 2007-10-01 | 2009-11-20 |
| FMS European Long-Term Study milnacipran, Placebo - Fibromyalgia Syndrome | Phase 3 | Completed | Pierre Fabre Medicament | 490 | 2006-09-01 | 2013-07-11 |
| Study of Milnacipran for the Treatment of Fibromyalgia Placebo, Milnacipran 100mg - Fibromyalgia | Phase 3 | Completed | Forest Laboratories | 1025 | 2006-04-01 | 2010-01-20 |
| A Multicentre Trial to Determine the Efficacy and Safety of Milnacipran in the Treatment of Fibromyalgia Syndrome milnacipran, Placebo - Fibromyalgia Syndrome | Phase 3 | Completed | Pierre Fabre Medicament | 1429 | 2006-02-01 | 2013-07-11 |
| Study of Milnacipran for the Treatment of Fibromyalgia milnacipran hydrochloride - Fibromyalgia | Phase 3 | Completed | Forest Laboratories | 1200 | 2004-11-01 | 2007-12-24 |
| Study Evaluating Effexor XR for Major Depression. Effexor XR, Milnacipran - Depression | Phase 3 | Completed | Wyeth is now a wholly owned subsidiary of Pfizer | 590 | 2004-06-01 | 2007-05-24 |
Fibromyalgia (9) · Depression (2) · Back Pain (1) · Coitus (1) · Diabetic Neuropathies (1) · Hypersensitivity (1) · Hypertension (1) · Motor Activity (1) · Neck Pain (1) · Neoplasms (1) · Neuralgia (1) · Pain (1) · Vulvodynia (1)
Forest Laboratories (4) · Pierre Fabre Medicament (2) · Banner Health (1) · Beth Israel Medical Center (1) · Brigham and Women's Hospital (1) · Columbia University (1) · Duke University (1) · University Hospital, Lille (1) · University of Tennessee (1) · Wyeth is now a wholly owned subsidiary of Pfizer (1)
United States (10) · France (3) · Czechia (2) · Finland (2) · Germany (2) · Italy (2) · Norway (2) · Portugal (2) · Romania (2) · Spain (2) · Sweden (2) · Denmark (1) · Japan (1) · Poland (1) · United Kingdom (1)
Allan Spera (2) · Ashwin A Patkar, MD (1) · Benjamin H Natelson, MD (1) · Candace S Brown, PharmD (1) · Sandra Jacobson, MD (1)
PMID 19108787, PMID 20156949, PMID 20496365, PMID 21459941, PMID 22429066, PMID 24188161, PMID 24800123, PMID 26335989
2014 (1)