14 completed, 2 unknown, 1 not yet recruiting, 1 recruiting. 6 Phase 1, 5 Not applicable, 3 Phase 4, 1 Early Phase 1, 1 Phase 2.
Follow Midazolam oral solution: new trials by email Literature Review of Midazolam oral solution trials Research Report on Midazolam oral solution
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Drug-Drug Interaction Study Between NTQ5082 Capsules and Midazolam Oral Solutio NTQ5082, Midazolam - Healthy Volunteers, Drug-Drug Interaction (DDI) | Phase 1 | Not yet recruiting | The Third Xiangya Hospital of Central South University | 18 | 2026-07-30 | 2026-08-04 |
| A Study to Assess the Effect of HRS-1301 on the Pharmacokinetics of Midazolam and Atorvastatin in Healthy Participants HRS-1301 Tablets, Atorvastatin Calcium Tablets, Midazolam oral solution - Hyperlipidemias | Phase 1 | Completed | Shandong Suncadia Medicine Co., Ltd. | 16 | 2026-06-08 | 2026-09-30 |
| KF2022#4-trial: Effects of a Beta Blocker and NSAID on CYP Mediated Drug Metabolism Caffeine Tablet, Bupropion Hydrochloride Capsels, Repaglinide Capsels - Drug Interaction | Not applicable | Completed | Helsinki University Central Hospital | 12 | 2024-08-22 | 2026-03-06 |
| Preoperative Oral Midazolam to Postoperative Pain Relief in Sleep Disturbance or Anxiety Patients With Colorectal Cancer Midazolam oral solution, Placebo - Preoperative, Sleep Disturbance | Not applicable | Recruiting | Sixth Affiliated Hospital, Sun Yat-sen University | 280 | 2024-07-24 | 2025-04-06 |
| Intranasal Dexmedetomidine Versus Oral Midazolam Premedication for Postoperative Negative Behavior Changes in Children Dexmedetomidine Hydrochloride, Midazolam, normal Saline - Behavior Problem | Phase 4 | Completed | Fujian Provincial Hospital | 324 | 2024-05-22 | 2026-07-30 |
| ED50 of Midazolam Oral Solution for Preoperative Hypnosis in Adults : An Up-and-Down Sequential Allocation Trial Midazolam oral solution - Dose, Midazolam | Not applicable | Completed | Sixth Affiliated Hospital, Sun Yat-sen University | 22 | 2023-09-05 | 2025-08-06 |
| Benzodiazepine Study for the Treatment of Seizure Clusters in a Third Level Mexican Neurological Center Midazolam oral solution, ClonazePAM Oral Product, Usual medication/ traditional - Cluster Seizure | Not applicable | Unknown | El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez | 150 | 2023-05-01 | 2024-05-31 |
| Effect of Estrogen Treatment on Drug Metabolism and Transport Midazolam oral solution, Digoxin Oral Tablet, Acetaminophen Oral Tablet - Transgender Persons | Phase 4 | Completed | University of Washington | 22 | 2022-11-01 | 2026-01-09 |
| PanACEA Sutezolid Dose-finding and Combination Evaluation Sutezolid, Bedaquiline, Delamanid, Moxifloxacin, Midazolam oral solution - Pulmonary Tuberculosis, Other Specified Pulmonary Tuberculosis | Phase 2 | Completed | Michael Hoelscher | 75 | 2021-05-06 | 2023-05-01 |
| Effect of Testosterone Treatment on Drug Metabolism and Transport Midazolam oral solution, Digoxin Oral Tablet, Acetaminophen Oral Tablet - Transgender Persons | Completed | University of Washington | 14 | 2021-05-01 | 2026-05-04 | |
| Nebulized vs. Oral Midazolam Sedation in Pediatric Anesthesia: A Randomized Comparative Study Midazolam nebulized, Midazolam oral solution - Preoperative Sedation | Not applicable | Completed | Cairo University | 72 | 2021-03-01 | 2022-04-11 |
| Handheld-multimedia Versus Oral Midazolam in Pediatric on Perioperative Anxiety Midazolam oral solution, IPAD - Perioperative Anxiety, Preanesthetic Medication | Phase 4 | Unknown | Universitair Ziekenhuis Brussel | 150 | 2020-02-01 | 2021-05-04 |
| A Clinical Drug-Drug Interaction (DDI) Study With Omaveloxolone Omaveloxolone, Midazolam oral solution, Repaglinide 1 MG - Healthy Adult Subjects | Phase 1 | Completed | Biogen | 61 | 2019-06-14 | 2025-05-30 |
| Assessing Goldenseal-drug Interactions Using a Probe Drug Cocktail Approach goldenseal, Metformin, Furosemide - Interaction Drug Food | Early Phase 1 | Completed | Washington State University | 16 | 2018-04-05 | 2023-04-28 |
| Pharmacokinetics of Midazolam, Dabigatran, Pitavastatin, Atorvastatin, and Rosuvastatin in Participants With Renal Insufficiency in the Presence and Absence of Rifampin (MK-0000-386) Midazolam oral solution, Dabigatran and pitavastatin oral solution, Atorvastatin and rosuvastatin oral solution - Renal Insufficiency | Phase 1 | Completed | Merck Sharp & Dohme LLC | 32 | 2018-03-01 | 2020-01-09 |
| Single and Multiple-Ascending Dose Study of CRN00808 in Healthy Volunteers CRN00808, Placebo Oral Solution, Midazolam oral solution - Healthy Volunteers | Phase 1 | Completed | Crinetics Pharmaceuticals Inc. | 99 | 2017-09-22 | 2018-08-29 |
| Premedication With Intranasal Dexmedetomidine or Midazolam for Prevention of Emergence Agitation in Children Dexmedetomidine, Midazolam oral solution, Oral saline - Emergence Delirium | Phase 3 | Completed | Brasilia University Hospital | 22 | 2017-06-01 | 2018-07-13 |
| Effects of Tipranavir (With Ritonavir) Capsule and Liquid Formulation on Cytochrome P450 and P-glycoprotein Activity in Healthy Volunteers Tipranavir capsule, Tipranavir solution, Ritonavir capsule - Healthy | Phase 1 | Completed | Boehringer Ingelheim | 34 | 2006-01-01 | 2014-09-18 |
Anxiety Disorders (2) · Emergence Delirium (2) · Colorectal Neoplasms (1) · Epilepsy (1) · Gram-Positive Bacterial Infections (1) · Hyperlipidemias (1) · Mental Disorders (1) · Pain, Postoperative (1) · Parasomnias (1) · Renal Insufficiency (1) · Tuberculosis (1) · Tuberculosis, Pulmonary (1)
Sixth Affiliated Hospital, Sun Yat-sen University (2) · University of Washington (2) · Biogen (1) · Boehringer Ingelheim (1) · Brasilia University Hospital (1) · Cairo University (1) · Crinetics Pharmaceuticals Inc. (1) · El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez (1) · Fujian Provincial Hospital (1) · Helsinki University Central Hospital (1) · Merck Sharp & Dohme LLC (1) · Michael Hoelscher (1) · Shandong Suncadia Medicine Co., Ltd. (1) · The Third Xiangya Hospital of Central South University (1) · Universitair Ziekenhuis Brussel (1)
United States (5) · China (4) · Australia (1) · Belgium (1) · Brazil (1) · Egypt (1) · Finland (1) · Mexico (1) · South Africa (1) · Tanzania (1)
Alex Van Hoorn, MD (1) · Jason Lickliter, MBBS PhD (1) · Jennifer Zon, MD (1) · Lauren Cirrincione, MPH,Pharm D (1) · Michael Hoelscher, Prof. (1) · Xiaochun Zheng, MD (1)
PMID 35000098, PMID 40645196, PMID 41452771
2019 (1), 2023 (1), K23GM147350 (1), U54AT008909 (1)