4 completed, 2 recruiting, 1 active not recruiting, 1 unknown. 8 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 8 | Completed 4, Recruiting 2, Active not recruiting 1, Unknown 1 |
| Phase 1 | 1 | Recruiting 1 |
| Phase 3 | 1 | Completed 1 |
Follow Midazolam Hydrochloride: new trials by email Literature Review of Midazolam Hydrochloride trials Research Report on Midazolam Hydrochloride
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT) Ketamine Hydrochloride, Midazolam Hydrochloride, Dialectical Behavioral Therapy (DBT) - Borderline Personality Disorder (BPD), Treatment-Resistant Major Depressive Disorder | Phase 2 | Recruiting | Joshua Rosenblat | 120 | 2026-07-16 | 2026-07-29 |
| Ketamine for Combined Depression and Alcohol Use Disorder Ketamine Hydrochloride, Midazolam Hydrochloride - Depression, Alcohol Use Disorder | Phase 1 / Phase 2 | Recruiting | University Hospital of North Norway | 34 | 2025-01-20 | 2026-06-23 |
| Ketamine for Methamphetamine Use Disorder Ketamine Hydrochloride, Midazolam Hydrochloride - Substance Use Disorders, Substance Use | Phase 2 | Completed | University of Texas Southwestern Medical Center | 120 | 2024-09-11 | 2026-10-27 |
| i-CBT and IV Ketamine for Suicidality in Treatment-Resistant Depression: A Randomized, Midazolam-Controlled Clinical Trial Ketamine hydrochloride, i-CBT (Internet-based Cognitive Behavioural Therapy), Midazolam Hydrochloride - Major Depressive Disorder, Suicide | Phase 2 | Active not recruiting | University Health Network, Toronto | 76 | 2024-01-02 | 2026-10-06 |
| Ketamine for Treatment-Resistant Bipolar Disorder Ketamine Hydrochloride, Midazolam Hydrochloride - Bipolar Disorder, Bipolar Depression | Phase 2 | Completed | Joshua Rosenblat | 71 | 2022-07-04 | 2026-03-05 |
| Investigation of Antidepressant Efficacy of Oral Ketamine Treatment Ketamine, Midazolam Hydrochloride - Major Depressive Episode | Phase 2 | Unknown | Medical University of Vienna | 60 | 2017-04-24 | 2019-09-03 |
| Understanding How Ketamine Brings About Rapid Improvement in OCD Ketamine, Midazolam - Obsessive-Compulsive Disorder | Phase 2 | Completed | Stanford University | 120 | 2016-08-16 | 2026-08-13 |
| Action of Ketamine in Treatment-Resistant Depression Ketamine, Midazolam - Treatment-resistant Depression | Phase 2 / Phase 3 | Completed | University of Ottawa | 46 | 2013-05-01 | 2018-06-26 |
Depressive Disorder, Treatment-Resistant (3) · Bipolar Disorder (2) · Depression (2) · Depressive Disorder, Major (2) · Alcoholism (1) · Behavior, Addictive (1) · Borderline Personality Disorder (1) · Obsessive-Compulsive Disorder (1) · Substance-Related Disorders (1) · Suicidal Ideation (1) · Suicide (1)
Joshua Rosenblat (2) · Medical University of Vienna (1) · Stanford University (1) · University Health Network, Toronto (1) · University Hospital of North Norway (1) · University of Ottawa (1) · University of Texas Southwestern Medical Center (1)
Canada (4) · United States (2) · Austria (1) · Norway (1)
Andreas W Blomkvist, M.D. (1) · Carolyn I Rodriguez, MD, PhD (1) · Joshua D. Rosenblat, MD, MSc (1) · Joshua Rosenblat, MD, MSc (1) · Madhukar Trivedi, MD (1) · Pierre Blier, M.D, Ph.D (1) · Rodrigo Mansur (1)
PMID 30922101, PMID 34971723, PMID 35267254, PMID 35931041, PMID 42684694
2023 (1)