6 completed, 3 terminated, 1 withdrawn. 10 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 10 | Completed 6, Terminated 3, Withdrawn 1 |
Follow Lupron: new trials by email Literature Review of Lupron trials Research Report on Lupron
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Regulation of Cervical Mucus Secretion Leuprolide acetate, Estrogen and Progesterone Replacement, Progestin - Fertility, Contraception | Phase 4 | Completed | Oregon Health and Science University | 5 | 2015-03-29 | 2019-10-18 |
| Efficacy of Recombinant FSH/GnRH Antagonist Protocol With and Without LH Adjunct for Egg Bank Donation Follistim, Ganirelix, Menotropins - Egg Donation | Phase 4 | Completed | Michigan Reproductive Medicine | 38 | 2014-04-01 | 2018-03-23 |
| Gene Expression Profile After Gonadotropin Releasing Hormone (GnRH) Agonist Trigger of Oocyte Maturation GnRH agonist, hCG - Endometrial Receptivity, Ovarian Hyperstimulation Syndrome | Phase 4 | Terminated | UConn Health | 7 | 2012-04-01 | 2018-11-21 |
| Levonorgestrel-releasing Intrauterine System in Patients With Endometriosis LNG-IUS: levonorgestrel intrauterine system, GnRHa: leuprolide - Endometriosis | Phase 4 | Completed | University of Sao Paulo | 44 | 2010-02-01 | 2015-01-21 |
| Impact of Hot Flashes on Sleep and Mood Disturbance leuprolide - Menopause, Depression | Phase 4 | Completed | Massachusetts General Hospital | 29 | 2009-11-03 | 2018-01-23 |
| Menopur® Versus Follistim® in Polycystic Ovarian Syndrome (PCOS) Menotropin, Progesterone vaginal insert, Follitropin beta - Polycystic Ovarian Syndrome, Infertility | Phase 4 | Completed | Ferring Pharmaceuticals | 110 | 2009-01-01 | 2012-01-27 |
| Oral Microdose Lupron Versus Luteal Estradiol Trial in Poor Responder In Vitro Fertilization (IVF) Patients Oral contraceptive pill and microdose lupron, E2 patch/antagonist - Infertility | Phase 4 | Withdrawn | Weill Medical College of Cornell University | 2009-01-01 | 2013-06-25 | |
| Understanding Experimentally Induced Hot Flushes Leuprolide acetate - Hot Flashes | Phase 4 | Completed | Massachusetts General Hospital | 20 | 2005-11-28 | 2018-09-18 |
| Polycystic Ovary Syndrome (PCOS) and Sleep Apnea continuous positive airway pressure (CPAP), depot leuprolide plus estrogen/progestin replacement, pioglitazone - Polycystic Ovary Syndrome, Obstructive Sleep Apnea | Phase 4 | Terminated | University of Chicago | 37 | 2003-09-01 | 2023-03-21 |
| Comparison of Trelstar Versus Lupron or Zoladex in Advanced Prostate Cancer Trelstar, Lupron, Zoladex - Prostate Cancer | Phase 4 | Terminated | Pharmatech | 41 | 2002-09-01 | 2016-04-25 |
Hot Flashes (2) · Infertility (2) · Polycystic Ovary Syndrome (2) · Depression (1) · Endometriosis (1) · Glucose Intolerance (1) · Insulin Resistance (1) · Metabolic Syndrome (1) · Neoplasms (1) · Ovarian Hyperstimulation Syndrome (1) · Parasomnias (1) · Prostatic Neoplasms (1) · Sleep Apnea, Obstructive (1) · Thrombosis (1)
Massachusetts General Hospital (2) · Ferring Pharmaceuticals (1) · Michigan Reproductive Medicine (1) · Oregon Health and Science University (1) · Pharmatech (1) · UConn Health (1) · University of Chicago (1) · University of Sao Paulo (1) · Weill Medical College of Cornell University (1)
United States (9) · Brazil (1)
David A Ehrmann, M.D. (1) · Esra Tasali, M.D. (1) · Eve Van Cauter, Ph.D. (1) · Hadine Joffe, M.D., M.Sc. (1) · Hadine Joffe, MD (1) · Lawrence Engmann, MD, MRCOG (1) · Leo Han, MD (1) · Michael Michael Manyak, MD (1) · Michael S Mersol-Barg, MD (1) · Zev Rosenwaks, M.D. (1)
PMID 18172212, PMID 18647805, PMID 21123449, PMID 22723326, PMID 24293774, PMID 25283586, PMID 25385669, PMID 26951410, PMID 27680875, PMID 29457758
R01HL075079 (1), R01MH082922 (1)