11 completed, 2 unknown, 1 not yet recruiting. 5 Phase 3, 3 Phase 2, 2 Phase 1, 2 Phase 4, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Completed 5 |
| Phase 2 | 3 | Completed 2, Unknown 1 |
| Phase 1 | 2 | Completed 2 |
| Phase 4 | 2 | Completed 2 |
| Not applicable | 1 | Unknown 1 |
Follow loxoprofen: new trials by email Literature Review of loxoprofen trials Research Report on loxoprofen
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Multimodal Imaging and Biospecimen Collection for Low Back Pain (LBPB) Nerve Block, endoscopic spinal disecetomy, Medication - Chronic Low Back Pain (CLBP), Acute Low Back Pain | Not yet recruiting | Peking University Third Hospital | 360 | 2025-05-15 | 2025-05-13 | |
| Pain Management After Transnasal Transsphenoidal Surgery for Pituitary Adenomas NSAID, Tramadol - Pituitary Adenoma, Surgery | Not applicable | Unknown | Peking Union Medical College Hospital | 202 | 2020-10-31 | 2020-11-03 |
| An in Vivo Bioequivalence Study of 2 Loxoprofen Sodium Products in Vietnamese Healthy Male Volunteers FABALOFEN 60, JAPROLOX TABLET - Bioequivalence | Phase 1 | Completed | Centre of Clinical Pharmacology, Hanoi Medical University | 24 | 2020-05-07 | 2021-03-18 |
| Clinical Research on the Efficacy of Bosinji on Herniated Intervertebral Disc of Lumbar Spine Bosinji, Loxonine tab., Acupuncture - Lumbar Disc Herniation | Phase 3 | Completed | Kyunghee University Medical Center | 74 | 2017-12-28 | 2020-02-05 |
| Japanese IP-TN Trial Loxoprofen sodium, Methocarbamol - Pain | Phase 3 | Completed | Boehringer Ingelheim | 80 | 2016-07-27 | 2018-07-20 |
| Comparative Study of Loxoprofen Sodium Transdermal Patch and Loxonin® Tablets for the Treatment of Acute Trauma Transdermal Patch, Loxoprofen sodium, Placebo (for loxoprofen sodium) - Trauma, Pain | Phase 3 | Completed | Daiichi Sankyo Brasil Farmacêutica LTDA | 242 | 2015-10-01 | 2017-02-14 |
| Low-dose Recombinant Human IL-2 for the Treatment of Rheumatoid Arthritis hrIL-2 active, hrIL-2 placebo, MTX - Rheumatoid Arthritis | Phase 2 | Completed | Peking University People's Hospital | 47 | 2015-07-01 | 2019-09-09 |
| Efficacy and Safety of Loxoprofen Hydrogel Patch in Patients With Ankylosing Spondylitis Loxoprofen sodium hydrogel patch, Loxoprofen sodium tablet - Ankylosing Spondylitis | Phase 4 | Completed | Sun Yat-sen University | 70 | 2015-05-25 | 2019-01-11 |
| East-West Collaboration Treatment Using Bee Venom Acupuncture and NSAIDs for Chronic Cervicalgia Bee Venom Acupuncture, Loxoprofen - Chronic Non-specific, Uncomplicated Neck Pain | Phase 2 | Completed | Kyunghee University Medical Center | 60 | 2013-07-01 | 2015-11-24 |
| Phase 3 Study of Pelubiprofen & Loxoprofen in Patients With Upper Respiratory Tract Infection Pelubiprofen, Loxoprofen - Acute Upper Respiratory Infection, Fever | Phase 3 | Completed | Daewon Pharmaceutical Co., Ltd. | 183 | 2013-01-01 | 2016-10-10 |
| Bee Venom Acupuncture for the Treatment of Chronic Low Back Pain Bee Venom Acupuncture Therapy, Loxoprofen, Placebo - Chronic Low Back Pain | Phase 2 | Unknown | Kyunghee University Medical Center | 54 | 2011-04-01 | 2012-03-21 |
| Study Of Celecoxib In Healthy Subjects Celecoxib, Loxoprofen, Placebo - Healthy Volunteers | Phase 4 | Completed | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | 190 | 2009-11-01 | 2021-02-02 |
| Drug-Drug Interaction Study of Esomeprazole (D961H) Capsule and Loxoprofen Tablet After Repeated Oral Administration in Japanese Males Esomeprazole (D961H), Loxoprofen - Healthy | Phase 1 | Completed | AstraZeneca | 30 | 2008-04-01 | 2009-03-12 |
| Comparison Of Celecoxib 200 Mg Bid, Loxoprofen Sodium 60 Mg Tid And Placebo In Low Back Pain In Japan Celecoxib, Placebo, Loxoprofen - Low Back Pain | Phase 3 | Completed | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | 1234 | 2004-10-01 | 2021-03-03 |
Low Back Pain (3) · Pain (3) · Acute Pain (1) · Agnosia (1) · Arthritis, Rheumatoid (1) · Chronic Pain (1) · Fever (1) · Fibromyalgia (1) · Intervertebral Disc Displacement (1) · Mental Disorders (1) · Neuralgia (1) · Nociplastic Pain (1) · Pituitary Neoplasms (1) · Radiculopathy (1) · Sleep Wake Disorders (1)
Kyunghee University Medical Center (3) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (2) · AstraZeneca (1) · Boehringer Ingelheim (1) · Centre of Clinical Pharmacology, Hanoi Medical University (1) · Daewon Pharmaceutical Co., Ltd. (1) · Daiichi Sankyo Brasil Farmacêutica LTDA (1) · Peking Union Medical College Hospital (1) · Peking University People's Hospital (1) · Peking University Third Hospital (1) · Sun Yat-sen University (1)
China (4) · Japan (4) · South Korea (4) · Brazil (1) · Vietnam (1)
Byung-Kwan Seo, PhD., KMD (2) · Bing Xing, MD (1) · Byung-Kwan Seo (1) · Dae-Jin Cho (1) · Jie Sun (1) · Jieruo Gu, Prof (1) · Jun-Hwan Lee (1) · Michio Yagi (1) · Naotsugu Oyama, MD, PhD (1) · Thanh P Nguyen, MD (1) · Wei Lian, MD (1) · Zhanguo Li, MD PhD (1)
PMID 10319217, PMID 10376632, PMID 10623981, PMID 15851777, PMID 17349504, PMID 2205779, PMID 23216412, PMID 23317340, PMID 24746224, PMID 30558079, PMID 3344884, PMID 3461421, PMID 35250032, PMID 3674268, PMID 39640075, PMID 40094866, PMID 7609956