9 completed, 1 terminated. 10 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 10 | Completed 9, Terminated 1 |
| Phase 2 | 1 | Completed 1 |
Follow Lovastatin: new trials by email Literature Review of Lovastatin trials Research Report on Lovastatin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Homozygous Familial Hypercholesterolemia Alirocumab SAR236553 (REGN727), Atorvastatin, Simvastatin - Hypercholesterolemia | Phase 3 | Completed | Sanofi | 18 | 2018-08-31 | 2020-12-29 |
| An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia Alirocumab SAR236553 (REGN727), Rosuvastatin, Atorvastatin - Hypercholesterolaemia | Phase 3 | Completed | Sanofi | 153 | 2018-05-31 | 2023-05-06 |
| Naturopathic Treatment for the Prevention of Cardiovascular Disease Naturopathic medicine. May include: fish oil, plant sterols, soluble fiber, cinnamon, coQ10 and exercise, Conventional medical treatment (Atorvastatin,Fluvastatin,Lovastatin,Pravastatin,Rosuvastatin,Simvastatin) - Cardiovascular Disease | Phase 3 | Completed | The Canadian College of Naturopathic Medicine | 300 | 2008-04-01 | 2010-05-17 |
| Efficacy of Lapaquistat Acetate Co-Administered With Statins in Subjects With Hypercholesterolemia Lapaquistat acetate and stable statin therapy, Stable statin therapy - Hypercholesterolemia | Phase 3 | Terminated | Takeda | 411 | 2007-07-01 | 2016-06-22 |
| The Dose Response of Niacin ER/Lovastatin on Peak Walking Time (PWT) in Patients With Intermittent Claudication - TROPIC Niacin Extended Release and Lovastatin Tablets - Intermittent Claudication, Peripheral Vascular Disease | Phase 3 | Completed | Kos Pharmaceuticals | 870 | 2003-10-01 | 2006-11-02 |
| Effect of Niacin ER/Lovastatin on Peak Walking Time & Claudication Onset Time in Patients With Intermittent Claudication Niacin Extended Release and Lovastatin Tablets - Intermittent Claudication, Peripheral Vascular Disease | Phase 3 | Completed | Kos Pharmaceuticals | 366 | 2003-01-01 | 2006-11-01 |
| A 6-Month Consumer Behavior Study of a Self-Management System (0803-084)(COMPLETED) MK0803, lovastatin, Self-Management System - Hypercholesterolemia | Phase 3 | Completed | Merck Sharp & Dohme LLC | 1000 | 2002-12-04 | 2017-10-02 |
| Post Coronary Artery Bypass Graft (CABG) Study lovastatin, cholestyramine, warfarin - Cardiovascular Diseases, Coronary Disease | Phase 3 | Completed | National Heart, Lung, and Blood Institute (NHLBI) | 1987-04-01 | 2016-04-14 | |
| MARS - Monitored Atherosclerosis Regression Study lovastatin - Atherosclerosis, Coronary Artery Disease | Phase 2 / Phase 3 | Completed | Merck Sharp & Dohme LLC | 270 | 1985-06-01 | 2009-12-11 |
| Familial Atherosclerosis Treatment Study lovastatin, colestipol, niacin - Cardiovascular Diseases, Coronary Arteriosclerosis | Phase 3 | Completed | University of Washington | 146 | 1984-01-01 | 2015-12-03 |
Hypercholesterolemia (4) · Atherosclerosis (3) · Cardiovascular Diseases (3) · Coronary Disease (3) · Coronary Artery Disease (2) · Heart Diseases (2) · Intermittent Claudication (2) · Myocardial Ischemia (2) · Peripheral Arterial Disease (2) · Peripheral Vascular Diseases (2) · Homozygous Familial Hypercholesterolemia (1) · Hyperlipidemias (1) · Hyperlipoproteinemia Type II (1)
Kos Pharmaceuticals (2) · Merck Sharp & Dohme LLC (2) · Sanofi (2) · National Heart, Lung, and Blood Institute (NHLBI) (1) · Takeda (1) · The Canadian College of Naturopathic Medicine (1) · University of Washington (1)
United States (4) · Canada (3) · Brazil (2) · Denmark (2) · Mexico (2) · Netherlands (2) · Russia (2) · Slovenia (2) · Spain (2) · Taiwan (2) · Turkey (Türkiye) (2) · Argentina (1) · Austria (1) · Bulgaria (1) · Czechia (1)
B. Greg Brown, M.D., Ph.D (1) · Dugald Seely, ND (1) · Genell Knatterud (1) · Howard N. Hodis, MD (1)
PMID 20212073, PMID 23630244, PMID 24451612, PMID 36325897, PMID 38315470
2017 (2), P01HL030086 (1)