13 completed, 4 recruiting, 3 terminated, 3 unknown. 16 Not applicable, 4 Phase 2, 2 Phase 1, 1 Early Phase 1, 1 Phase 4.
Follow Light: new trials by email Literature Review of Light trials Research Report on Light
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Longitudinal Natural History Study of Retinal Function in Eyes of Patients With Diabetes Visual Acuity, Reading Speed, Visual Field testing - Diabetic Retinal Disease | Recruiting | Jaeb Center for Health Research | 450 | 2026-06-01 | 2026-10-23 | |
| Sleep Health in U.S. Marines Sleep Leadership, Circadian, Light, and Sleep Skills in Shipboard Military (CLASS-MC) Personnel Program, Insomnia Coach - Depression, Suicidality | Phase 2 | Recruiting | San Diego State University | 860 | 2026-03-31 | 2026-04-16 |
| "Physiological Responses to Manual Pressure in Healthy Adults" "Manual Pressure Protocol", Manual Therapy Protocols (DLM, light and moderate-pressure massage), Graded Sustained Pressure - Healthy Participants | Not applicable | Not yet recruiting | Universidad Europea de Madrid | 90 | 2026-03-01 | 2026-02-06 |
| Pupillometry in Delayed Sleep Wake Phase Disorder Light and Citalopram - Delayed Sleep-Wake Phase Disorder | Not applicable | Recruiting | Northwestern University | 220 | 2025-09-01 | 2026-06-08 |
| Effect of Light Level on Stress, Anxiety, Psychological Well-being in Pregnant Women light - Stress, Anxiety | Not applicable | Unknown | Emine Yıldırım | 60 | 2024-07-25 | 2024-07-17 |
| A Municipality Implemented Behavioural Intervention to Improve Quality of Life Among Older Adults 'Light, activity and sleep in my daily life' intervention - Quality of Life | Not applicable | Recruiting | Lund University | 40 | 2024-05-15 | 2025-02-04 |
| The Impact of Low Level Laser Treatment on Skeletal Muscle and Skin Tissue Laser therapy, Sham - Muscles Metabolism, Skin Metabolism | Not applicable | Completed | Maastricht University Medical Center | 13 | 2024-04-01 | 2024-12-05 |
| Omega-3 Monoglyceride Based Topic Products as Skin Prebiotics for Eczema Omega-3 monoglyceride based topical Serum and cream of formulation A (light), Omega-3 monoglyceride based topical Serum and cream of formulation B (rich) - Eczema | Not applicable | Terminated | SCF Pharma | 7 | 2023-12-20 | 2026-04-22 |
| Treatment of Mycosis Fungoides With Hypericin Ointment and Visible Light Hypericin, Visible Light - Cutaneous T Cell Lymphoma, Mycosis Fungoides | Phase 2 | Completed | Ellen Kim, MD | 10 | 2023-08-21 | 2026-02-09 |
| Assessment of Visual Dyslexia Remediation Protocols - Dyslexia REMEDIATION visual stimulation with I pad, visual stimulation with lamp - Dyslexia | Not applicable | Completed | Hospices Civils de Lyon | 13 | 2022-11-17 | 2024-09-25 |
| Dose-dependent Impact of Daytime Lighting on Evening Responses to Light Light - Sleep | Not applicable | Unknown | Palo Alto Veterans Institute for Research | 48 | 2022-07-01 | 2022-03-17 |
| Shifting Sleep Timing in Teens Light, CBT, Sham Light - Sleep Insufficiency, Sleep | Not applicable | Active not recruiting | Stanford University | 160 | 2022-07-01 | 2026-09-25 |
| Evaluation of Less Invasive Procedures for Visceral Leishmaniasis Treatment Efficacy Monitoring Test of Cure ELISA, LAMP, Cytokine Release Assay - Visceral Leishmaniasis | Completed | Foundation for Innovative New Diagnostics, Switzerland | 60 | 2021-09-01 | 2026-09-17 | |
| Effects of Light and Sound Modification on Sleep Quality and Circadian Rhythm in the MICU Patients light and sound modification (earplugs and eye masks) - Intensive Care Unit, Ventilator | Not applicable | Completed | Shin Kong Wu Ho-Su Memorial Hospital | 112 | 2020-01-05 | 2021-02-10 |
| Survey of the Facial Bacteriome fluorescence imaging with 405nm light - Understanding Skin Health and the Microbiome, Microbial Colonization | Completed | University Health Network, Toronto | 30 | 2019-11-25 | 2021-03-29 | |
| Effect of Topical Sulforaphane on Skin Aging and With Ultraviolet and Visible Light Exposure Sulforaphane (broccoli sprout extract), UV or visible light - Skin Aging | Early Phase 1 | Active not recruiting | Johns Hopkins University | 12 | 2019-10-09 | 2026-09-04 |
| Bright Light Therapy in the Treatment of Non-seasonal Bipolar Depression Light - Bipolar Depression | Phase 1 / Phase 2 | Unknown | Assistance Publique - Hôpitaux de Paris | 45 | 2019-09-30 | 2020-02-10 |
| The Impact of Artificial Sunlight on Human Sleep and Circadian Rhythms Light - Sleep, Circadian Dysregulation | Not applicable | Completed | VA Palo Alto Health Care System | 10 | 2019-07-01 | 2021-03-30 |
| Dawn Simulation and Postural Hypotension Light - Orthostatic Hypotension | Phase 4 | Completed | VA Palo Alto Health Care System | 35 | 2016-09-01 | 2019-10-25 |
| Effects of Light and Exercise on Human Circadian Rhythms and Performance Light and exercise - Circadian Rhythm | Not applicable | Completed | Brigham and Women's Hospital | 8 | 2016-04-01 | 2018-07-11 |
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Sleep Initiation and Maintenance Disorders (2) · Acne Vulgaris (1) · Adolescent Behavior (1) · Anxiety Disorders (1) · Bipolar Disorder (1) · Blindness (1) · Chronobiology Disorders (1) · Communicable Diseases (1) · Depression (1) · Dermatitis (1) · Dermatitis, Phototoxic (1) · Disorders of Excessive Somnolence (1) · Dyslexia (1) · Eczema (1) · Hypotension, Orthostatic (1)
VA Palo Alto Health Care System (4) · Northwestern University (2) · Assistance Publique - Hôpitaux de Paris (1) · Brigham and Women's Hospital (1) · Ellen Kim, MD (1) · Emine Yıldırım (1) · Foundation for Innovative New Diagnostics, Switzerland (1) · Hospices Civils de Lyon (1) · Jaeb Center for Health Research (1) · Johns Hopkins University (1) · Lund University (1) · Maastricht University Medical Center (1) · Oregon Health and Science University (1) · Palo Alto Veterans Institute for Research (1) · Photopharmica (1)
United States (14) · Canada (2) · France (2) · Ethiopia (1) · Netherlands (1) · Spain (1) · Sweden (1) · Taiwan (1) · United Kingdom (1)
Alfred Lewy, MD, PhD (1) · Anna Chien (1) · Elizabeth B Klerman, MD PhD (1) · Emily Schmied, PhD (1) · Hui-Mei Chen, PhD (1) · Keith Harding, MBChB FRCS (1) · Murad Alam, MD (1) · Samuel P Fortin, Ph.D (1)
PMID 25230376, PMID 25594808, PMID 26785964, PMID 27109818, PMID 29358448, PMID 29452801, PMID 30113379, PMID 30215172, PMID 30466205, PMID 32307533, PMID 40608475, PMID 41180604, PMID 41827051, PMID 42029912
R01HL174661 (1), UG1EY014231 (1)