30 completed, 15 recruiting, 15 unknown, 12 not yet recruiting. 46 Not applicable, 21 Phase 4, 8 Phase 3, 5 Phase 2.
Follow Intrathecal Morphine: new trials by email Literature Review of Intrathecal Morphine trials Research Report on Intrathecal Morphine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pain After Scheduled Cesarean Delivery: Spinal Morphine With or Without Levobupivacaine Wound Infiltration Levobupivacaine, Intrathecal Morphine - Pain Management, C Section | Not yet recruiting | Fundación Santa Fe de Bogota | 336 | 2026-10-14 | 2026-10-06 | |
| Ultrasound-Guided Posterior Quadratus Lumborum Block With Bupivacaine and Dexmedetomidine Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean Delivery Intrathecal Morphine, Ultrasound-Guided Posterior Quadratus Lumborum Block - Postoperative Analgesia After Cesarean Delivery | Phase 4 | Not yet recruiting | Assiut University | 80 | 2026-10-01 | 2026-09-08 |
| ITM vs ITM+Clonidine for Lumbar Fusions Intrathecal Morphine + Intrathecal Clonidine, Intrathecal Morphine - Lumbar Fusion Surgery | Phase 3 | Not yet recruiting | MaineHealth | 70 | 2026-10-01 | 2026-10-05 |
| PENG Block Versus Intrathecal Morphine for Early Postoperative Recovery After Total Hip Arthroplasty Pericapsular nerve group (PENG) block, Intrathecal Morphine - Postoperative Pain | Not applicable | Not yet recruiting | Erzincan Binali Yildirim Universitesi | 90 | 2026-09-01 | 2026-09-09 |
| Lateral QL Block vs Intrathecal Morphine for Cesarean Section Lateral Quadratus Lumborum Block, ıv morphine PCA, Intrathecal morphine - Anesthesia, Postoperative Pain | Not applicable | Not yet recruiting | Ondokuz Mayıs University | 56 | 2026-07-15 | 2026-07-17 |
| Intrathecal Morphine Versus Intrathecal Dexmedetomidine Compared to Placebo for Postoperative Pain Relief After Spine Fixation Surgeries Intrathecal Morphine, Intrathecal Dexmedetomidine, Normal Saline - Intrathecal Morphine, Intrathecal Dexmedetomidine | Not applicable | Recruiting | Tanta University | 90 | 2026-07-01 | 2026-08-20 |
| Efficacy of Adding Intrathecal Morphine to Erector Spinae Plane Block for Postoperative Analgesia After Midline Laparotomy Intrathecal Morphine, Erector Spinae Plane Block - Postoperative Pain, Midline Laparotomy | Not applicable | Recruiting | Sohag University | 75 | 2026-07-01 | 2026-07-22 |
| Transversalis Fascia Plane Block Versus Low-Dose Intrathecal Morphine for Open Inguinal Hernia Repair Intrathecal morphine, Ultrasound-guided transversalis fascia plane block - Postoperative Pain | Not applicable | Recruiting | Hitit University | 80 | 2026-06-23 | 2026-07-14 |
| Comparison of Spinal Anesthesia With Intrathecal Morphine Versus PENG Block With or Without Dexamethasone in Hip Arthroplasty Intrathecal Morphine, Pericapsular Nerve Group Block, Dexamethasone - Arthropathy of Hip, Hip Osteoarthritis | Not applicable | Not yet recruiting | Poznan University of Medical Sciences | 90 | 2026-06-01 | 2026-05-13 |
| Intrathecal Morphine for Quality of Recovery After Open Abdominal Surgery Within an Enhanced Recovery Pathway Intrathecal Morphine, Intrathecal saline injection, TAPB - Open Abdominal Surgery | Not applicable | Not yet recruiting | Sun Yat-sen University | 756 | 2026-05-01 | 2026-05-08 |
| Serratus Posterior Superior Intercostal Plane Block Versus Intrathecal Morphine in VATS Intrathecal Morphine, Serratus Posterior Superior Intercostal Plane Block - Thoracic Anesthesia, Postoperative Pain | Not applicable | Completed | Ondokuz Mayıs University | 60 | 2026-04-15 | 2026-10-05 |
| Intrathecal MoRphine Versus Transabdominal Plane Block (TAP) Block for AnalGesic Management in Elective Caesarean Section Intrathecal Morphine, TAP Block - Pregnancy, Cesarean Section | Phase 4 | Not yet recruiting | Istituto Giannina Gaslini | 100 | 2026-03-01 | 2026-01-30 |
| Analgesic Efficacy of Bupivacaine Infiltration, Erector Spinae Plane Block, and Intrathecal Morphine in Laparoscopic Cholecystectomy Bupivacaine Infiltration, Erector Spinae Plane Block, Intrathecal Morphine - Postoperative Pain Management, Cholecystectomy, Laparoscopic | Not applicable | Not yet recruiting | Ataturk University | 132 | 2025-12-01 | 2025-11-25 |
| Intrathecal Morphine for Recovery and Outcomes After VATS Intrathecal Morphine, Serratus Anterior Plane Block (SAPB) group, Dexmedetomidine - Postoperative Pain Management in Video-Assisted Thoracoscopic Surgery | Not applicable | Completed | Ataturk University | 64 | 2025-12-01 | 2026-09-03 |
| Intrathecal Morphine Versus Trocar-Site and Intraperitoneal Bupivacaine for Quality of Recovery After Laparoscopic Hysterectomy Intrathecal Morphine, Trocar-Site Bupivacaine Infiltration, Intraperitoneal Bupivacaine spray - Postoperative Pain Management, Laparoscopic Hysterectomy | Not applicable | Recruiting | Ataturk University | 64 | 2025-12-01 | 2025-12-08 |
| Comparison of Intrathecal Bupivacaine With and Without Morphine for Post-operative Analgesia in Parturients Undergoing Elective Cesarean Section: A Randomized Controlled Trial Intrathecal morphine with bupivacaine, Hyperbaric Bupivicaine - Postoperative Pain, Cesarean Delivery | Phase 4 | Not yet recruiting | Tribhuvan University Teaching Hospital, Institute Of Medicine. | 92 | 2025-10-15 | 2025-07-30 |
| Comparison of the Postoperative Analgesic Effects of ITM and Bi-level ESPB in Liver Transplantation Donors Intrathecal Morphine, Bi-level Erector Spinae Plane Block - Liver Transplantation, Pain Management | Not applicable | Recruiting | Ankara Etlik City Hospital | 60 | 2025-08-18 | 2025-08-19 |
| Efficacy and Safety of Intrathecal Morphine for Postoperative Pain Management Following Planned Caesarean Section Intrathecal Morphine, Placebo (Sodium Chloride Injection, 0.9%) - Caesarean Section, Postoperative Pain | Phase 4 | Recruiting | Anne Juul Wikkelsø | 1312 | 2025-07-15 | 2026-09-11 |
| Post-Operative Urinary Retention on Revision Knee Arthroplasty: the Role of Intrathecal Morphine Intrathecal Morphine, No Intrathecal Morphine - Arthroplasties, Knee Replacement, Nerve Block | Phase 3 | Recruiting | University of Toronto | 50 | 2025-06-24 | 2025-12-29 |
| ESPB vs Intrathecal Morphine for Assessements of Quality of Recovery After Cesarean Section Erector spinae plane block, Intrathecal morphine - Cesarean Section, Post Operative Pain | Not applicable | Recruiting | AUSL Romagna Rimini | 52 | 2025-06-18 | 2025-10-01 |
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Pain, Postoperative (33) · Agnosia (23) · Pain (7) · Colorectal Neoplasms (3) · Labor Pain (3) · Liver Neoplasms (2) · Acute Pain (1) · Chronic Pain (1) · Hernia (1) · Hernia, Inguinal (1) · Hypercapnia (1) · Hypotension (1) · Hypoxia (1) · Inflammation (1) · Liver Diseases (1)
Assiut University (8) · Ataturk University (5) · Ondokuz Mayıs University (4) · Ain Shams University (2) · Cork University Hospital (2) · Mahidol University (2) · Meri Mirceta (2) · Samuel Lunenfeld Research Institute, Mount Sinai Hospital (2) · Sun Yat-sen University (2) · Tanta University (2) · AUSL Romagna Rimini (1) · Alaa Ali Mohamed Elzohry (1) · Ankara Etlik City Hospital (1) · Anne Juul Wikkelsø (1) · Bursa City Hospital (1)
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Pawinee Pangthipampai, M.D. (2) · Ahmed S Basyouni, MD (1) · Albert Moore, MD (1) · Alex Grunfeld, MD (1) · Ali Ahiskalioglu, Prof. (1) · Andrea Cornini, MD (1) · Andrew Kwikiriza, MD (1) · Burhan Dost (1) · Cengiz Kaya, MD (1) · Danny F Hoogma, MD, PhD (1) · Denise M McCarthy, MB FCARCSI (1) · Denise M McCarthy, MB FCARSCI (1)
PMID 10740540, PMID 11359226, PMID 12059890, PMID 18699897, PMID 19104358, PMID 19750306, PMID 22150410, PMID 23076897, PMID 24570244, PMID 24738803, PMID 25536092, PMID 26655725, PMID 29856176, PMID 30229370, PMID 30640244, PMID 32112166, PMID 32412986, PMID 33761894, PMID 35991778, PMID 39039833, PMID 40609218, PMID 40639953, PMID 40662757, PMID 41408168, PMID 41433024, PMID 42185960, PMID 42228944, PMID 42464120, PMID 7760614, PMID 8831313
2014 (1)