18 completed. 18 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 18 | Completed 18 |
| Phase 2 | 1 | Completed 1 |
Follow Inhalation: new trials by email Literature Review of Inhalation trials Research Report on Inhalation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate the Safety and Efficacy of HL231 Solution for Inhalation in Patients With COPD HL231 Solution for Inhalation, Ultibro 110μg/50 μg - Chronic Obstructive Pulmonary Disease (COPD) | Phase 3 | Completed | Haisco Pharmaceutical Group Co., Ltd. | 487 | 2023-12-11 | 2026-04-06 |
| Anti-IgE Monoclonal Antibody Treatment in Patients With Allergic Asthma. CMAB007, Symbicort, Seretide - Asthma, Allergic | Phase 3 | Completed | Shanghai Biomabs Pharmaceutical Co., Ltd. | 393 | 2018-05-09 | 2021-10-11 |
| AMPLIFY - D6571C00001 Duaklir USA Phase III Study Aclidinium bromide 400 μg/Formoterol Fumarate 12 μg (AB/FF 400/12 μg), Aclidinium bromide 400 μg (AB 400 μg), Formoterol fumarate 12 μg (FF 12 μg) - Chronic Obstructive Pulmonary Disease | Phase 3 | Completed | AstraZeneca | 1595 | 2016-07-05 | 2018-11-09 |
| Study to Evaluate Efficacy of LAI When Added to Multi-drug Regimen Compared to Multi-drug Regimen Alone LAI (Liposomal Amikacin for Inhalation) 590 mg - Mycobacterium Infections, Nontuberculous | Phase 3 | Completed | Insmed Incorporated | 336 | 2015-05-27 | 2020-05-07 |
| Comparing the Efficacy of Bricanyl M2 and Bricanyl M3 at 0.5 and 1.5 mg Dose Levels, to Allow for a Switch From Bricanyl Turbuhaler M2 to Bricanyl Turbuhaler M3 Terbutaline sulphate, Placebo for terbutaline sulphate - Asthma | Phase 3 | Completed | AstraZeneca | 95 | 2015-03-01 | 2017-01-13 |
| OPTIMIZing Treatment for Early Pseudomonas Aeruginosa Infection in Cystic Fibrosis azithromycin, placebo, Tobramycin solution for inhalation - Cystic Fibrosis | Phase 3 | Completed | Bonnie Ramsey | 221 | 2014-06-01 | 2019-10-01 |
| Phase 3 Study With Ciprofloxacin Dispersion for Inhalation in Non-CF Bronchiectasis (ORBIT-4) Ciprofloxacin dispersion for inhalation, Placebo - Non Cystic Fibrosis Bronchiectasis | Phase 3 | Completed | Aradigm Corporation | 304 | 2014-05-28 | 2021-03-26 |
| Ciprofloxacin Dry Powder for Inhalation (DPI) in Non-cystic Fibrosis Bronchiectasis (Non-CF BE) Ciprofloxacin (BAYQ3939) dry powder for inhalation, Placebo - Bronchiectasis | Phase 3 | Completed | Bayer | 521 | 2014-04-30 | 2017-10-02 |
| Phase 3 Study With Ciprofloxacin Dispersion for Inhalation in Non-CF Bronchiectasis (ORBIT-3) Ciprofloxacin dispersion for inhalation, Placebo - Non Cystic Fibrosis Bronchiectasis | Phase 3 | Completed | Aradigm Corporation | 278 | 2014-03-31 | 2021-03-26 |
| Extension Study of Liposomal Amikacin for Inhalation in Cystic Fibrosis (CF) Patients With Chronic Pseudomonas Aeruginosa (Pa) Infection Liposomal amikacin for inhalation - Cystic Fibrosis | Phase 3 | Completed | Insmed Incorporated | 206 | 2012-10-05 | 2020-06-17 |
| Efficacy of 3% Hypertonic Saline in Acute Viral Bronchiolitis 3% Saline, 0.9% Normal Saline - Acute Viral Bronchiolitis | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 778 | 2012-10-01 | 2014-07-28 |
| Study to Evaluate Arikayce™ in CF Patients With Chronic Pseudomonas Aeruginosa Infections Liposomal amikacin for inhalation (Arikayce™) using the PARI Investigational eFlow® Nebulizer., Tobramycin inhalation solution using a PARI LC® Plus nebulizer. - Pseudomonas Aeruginosa Infection | Phase 3 | Completed | Insmed Incorporated | 302 | 2012-02-29 | 2020-06-16 |
| Trial of Aeroquin Versus Tobramycin Inhalation Solution (TIS) in Cystic Fibrosis (CF) Patients MP-376 (Levofloxacin Solution for Inhalation), TIS (Tobramycin Inhalation Solution) - Cystic Fibrosis | Phase 3 | Completed | Amgen | 282 | 2011-01-01 | 2024-12-13 |
| International Study Evaluating the Safety and Efficacy of Inhaled, Human, Alpha-1 Antitrypsin (AAT) in Alpha-1 Antitrypsin Deficient Patients With Emphysema Kamada AAT for inhalation, Placebo - Emphysema | Phase 2 / Phase 3 | Completed | Kamada, Ltd. | 168 | 2009-12-01 | 2019-11-29 |
| Safety of Tobramycin Inhalation Powder (TIP) vs Tobramycin Solution for Inhalation in Patients With Cystic Fibrosis Tobramycin Inhalation Powder, Tobramycin Solution for Inhalation - Cystic Fibrosis | Phase 3 | Completed | Novartis Pharmaceuticals | 517 | 2006-02-01 | 2012-07-24 |
| Comparison of Inhaled Nitric Oxide and Oxygen in Participants Reactivity During Acute Pulmonary Vasodilator Testing Nitric Oxide for inhalation, Oxygen, Nitric Oxide plus Oxygen - Idiopathic Pulmonary Arterial Hypertension, Cardiomyopathy | Phase 3 | Completed | Mallinckrodt | 136 | 2004-09-01 | 2019-12-20 |
| Efficacy and Safety of 28 or 56 Day Treatment for Pseudomonas Aeruginosa in Children With Cystic Fibrosis Tobramycin solution for inhalation 300 mg - Cystic Fibrosis | Phase 3 | Completed | Novartis | 123 | 2003-11-01 | 2011-08-29 |
| A Study to Diagnose Lung Cancer by Sputum Cytology (01-312) Uridine 5'-Triphosphate (UTP) Solution for Inhalation - Lung Cancer | Phase 3 | Completed | Merck Sharp & Dohme LLC | 700 | 2001-04-01 | 2015-09-04 |
Cystic Fibrosis (6) · Pseudomonas Infections (3) · Respiratory Tract Infections (3) · Asthma (2) · Bronchiectasis (2) · Pulmonary Disease, Chronic Obstructive (2) · Acute Lung Injury (1) · Bronchial Diseases (1) · Bronchiolitis (1) · Bronchiolitis, Viral (1) · Cardiomyopathies (1) · Emphysema (1) · Familial Primary Pulmonary Hypertension (1) · Heart Defects, Congenital (1) · Lung Diseases, Obstructive (1)
Insmed Incorporated (3) · Aradigm Corporation (2) · AstraZeneca (2) · Amgen (1) · Assistance Publique - Hôpitaux de Paris (1) · Bayer (1) · Bonnie Ramsey (1) · Haisco Pharmaceutical Group Co., Ltd. (1) · Kamada, Ltd. (1) · Mallinckrodt (1) · Merck Sharp & Dohme LLC (1) · Novartis (1) · Novartis Pharmaceuticals (1) · Shanghai Biomabs Pharmaceutical Co., Ltd. (1)
United Kingdom (9) · Germany (8) · United States (8) · Canada (7) · France (7) · Netherlands (7) · Spain (7) · Hungary (6) · Poland (6) · Ireland (5) · Israel (5) · Italy (5) · Australia (4) · Bulgaria (4) · Austria (3)
Gina Eagle, MD (3) · Bonnie Ramsey, MD (1) · Felix Ratjen (1) · Jan Stolk, Professor (1) · Leif Bjermer, MD, Professor (1) · Michael Konstan, MD (1) · Nanshan Zhong, M.D. (1) · Nicole Hamblett, PhD (1) · Sanjay Sethi (1) · Vincent Gajdos, MD, PhD (1)
PMID 30658914, PMID 32554534, PMID 19996339, PMID 20405117, PMID 26935334, PMID 28232118, PMID 28495619, PMID 28586918, PMID 29371384, PMID 29890086, PMID 30216086, PMID 30962681, PMID 31451351, PMID 31467115, PMID 33595792, PMID 33887244, PMID 34144923, PMID 38277865, PMID 41186908, PMID 41345745
2004 (1), 2014 (1), U01HL114589 (1), U01HL114623 (1)