15 completed, 8 terminated, 4 unknown, 1 withdrawn. 28 Phase 2, 6 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 28 | Completed 15, Terminated 8, Unknown 4, Withdrawn 1 |
| Phase 1 | 6 | Completed 2, Terminated 2, Unknown 1, Withdrawn 1 |
Follow Immunoenzyme Techniques: new trials by email Literature Review of Immunoenzyme Techniques trials Research Report on Immunoenzyme Techniques
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Laboratory-Treated T Cells and Ipilimumab in Treating Patients With Metastatic Melanoma ipilimumab, cyclophosphamide, biopsy - Recurrent Melanoma, Stage IV Melanoma | Phase 1 / Phase 2 | Completed | Fred Hutchinson Cancer Center | 10 | 2009-02-01 | 2017-04-19 |
| Paricalcitol in Treating Patients With Advanced Prostate Cancer and Bone Metastases paricalcitol, immunoenzyme technique, laboratory biomarker analysis - Metastatic Cancer, Prostate Cancer | Phase 2 | Terminated | Wake Forest University Health Sciences | 2 | 2009-01-01 | 2018-07-06 |
| Trastuzumab, Cyclophosphamide, and Vaccine Therapy in Treating Patients With High-Risk or Metastatic Breast Cancer allogeneic GM-CSF-secreting breast cancer vaccine, trastuzumab, cyclophosphamide - Breast Cancer | Phase 2 | Completed | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 20 | 2008-12-01 | 2018-09-26 |
| Topical Imiquimod and Abraxane in Treating Patients With Advanced Breast Cancer imiquimod, Abraxane, laboratory biomarker analysis - Male Breast Cancer, Recurrent Breast Cancer | Phase 2 | Completed | University of Washington | 15 | 2008-12-01 | 2018-01-02 |
| Donor Stem Cell Transplant, Pentostatin, and Total-Body Irradiation in Treating Patients With Hematological Cancer cyclosporine, mycophenolate mofetil, pentostatin - Chronic Myeloproliferative Disorders, Leukemia | Phase 1 / Phase 2 | Withdrawn | University of Nebraska | 2008-09-01 | 2023-08-14 | |
| Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer carboplatin, paclitaxel albumin-stabilized nanoparticle formulation, protein expression analysis - Lung Cancer | Phase 2 | Completed | Greg Otterson | 63 | 2008-08-14 | 2018-04-02 |
| Gemcitabine and Carboplatin Followed By Laboratory-Treated T Lymphocytes in Treating Patients With Metastatic or Locally Recurrent Epstein-Barr Virus-Positive Nasopharyngeal Cancer autologous Epstein-Barr virus-specific cytotoxic T lymphocytes, carboplatin, gemcitabine hydrochloride - Head and Neck Cancer | Phase 2 | Unknown | National Cancer Centre, Singapore | 35 | 2008-07-01 | 2009-06-29 |
| Cetuximab, Combination Chemotherapy, and Radiation Therapy in Treating Patients With Newly Diagnosed Stage III or Stage IV Head and Neck Cancer That Cannot Be Removed By Surgery cetuximab, carboplatin, cisplatin - Head and Neck Cancer | Phase 2 | Terminated | European Organisation for Research and Treatment of Cancer - EORTC | 47 | 2008-02-01 | 2018-07-09 |
| Erlotinib, Docetaxel, and Radiation Therapy in Stage III or Stage IV Squamous Cell Carcinoma of the Head and Neck docetaxel, erlotinib hydrochloride, fluorescence in situ hybridization - Head and Neck Cancer | Phase 2 | Completed | Case Comprehensive Cancer Center | 43 | 2007-11-19 | 2024-08-22 |
| Vaccine Therapy and Celecoxib in Treating Patients With Metastatic Nasopharyngeal Cancer Ad5F35-LMP1/LMP2-transduced autologous dendritic cells, celecoxib, flow cytometry - Head and Neck Cancer | Phase 2 | Unknown | National Cancer Centre, Singapore | 35 | 2007-11-01 | 2013-12-18 |
| Liver Cancer Prevention Trial in Patients With Chronic Hep C Infection S-adenosyl-L-methionine disulfate p-toluene-sulfonate, placebo, laboratory biomarker analysis - Adult Primary Liver Cancer, Hepatitis C Infection | Phase 2 | Completed | Chao Family Comprehensive Cancer Center | 110 | 2007-10-01 | 2018-08-10 |
| Dasatinib in Treating Patients With Stage IV Pancreatic Cancer dasatinib, immunoenzyme technique, immunohistochemistry staining method - Pancreatic Cancer | Phase 2 | Terminated | City of Hope Medical Center | 7 | 2007-09-01 | 2015-10-05 |
| Sorafenib in Treating Patients With Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cancer in at Least the Second Remission sorafenib tosylate, immunoenzyme technique, immunohistochemistry staining method - Fallopian Tube Cancer, Ovarian Cancer | Phase 2 | Terminated | Memorial Sloan Kettering Cancer Center | 6 | 2007-07-01 | 2016-02-29 |
| Temozolomide in Treating Patients With Recurrent Glioblastoma Multiforme or Other Malignant Glioma temozolomide, protein expression analysis, reverse transcriptase-polymerase chain reaction - Brain and Central Nervous System Tumors | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 47 | 2007-06-01 | 2016-02-29 |
| Floxuridine and Dexamethasone as a Hepatic Arterial Infusion and Bevacizumab in Treating Patients With Primary Liver Cancer That Cannot be Removed by Surgery bevacizumab, dexamethasone, floxuridine - Liver Cancer | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 22 | 2007-05-09 | 2024-12-10 |
| Combination Chemotherapy and Interferon Alfa-2b in Treating Patients With Nonmetastatic Liver Cancer That Cannot Be Removed by Surgery recombinant interferon alfa-2b, doxorubicin hydrochloride, fluorouracil - Liver Cancer | Phase 2 | Unknown | National Cancer Centre, Singapore | 54 | 2007-03-01 | 2011-06-22 |
| Defined Green Tea Catechin Extract in Treating Patients With Localized Prostate Cancer Undergoing Surgery defined green tea catechin extract, placebo, immunohistochemistry staining method - Stage I Prostate Cancer, Stage IIA Prostate Cancer | Phase 2 | Terminated | Case Comprehensive Cancer Center | 5 | 2006-10-01 | 2012-03-15 |
| Laboratory Test in Predicting Response to Erlotinib in Patients With Relapsed Metastatic or Unresectable Non-Small Cell Lung Cancer That Did Not Respond to Previous Treatment erlotinib hydrochloride, gene expression analysis, protein expression analysis - Lung Cancer | Phase 2 | Completed | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 40 | 2006-09-01 | 2010-08-09 |
| Docetaxel and Bortezomib in Treating Patients With Progressive or Recurrent Non-Small Cell Lung Cancer docetaxel, bortezomib, laboratory biomarker analysis - Non-small Cell Lung Cancer, Recurrent Non-small Cell Lung Cancer | Phase 2 | Completed | National Cancer Institute (NCI) | 81 | 2006-07-01 | 2017-12-05 |
| Celecoxib in Treating Patients With Head and Neck Cancer That Can Be Removed By Surgery celecoxib, microarray analysis, protein expression analysis - Head and Neck Cancer | Phase 1 / Phase 2 | Unknown | Centre Hospitalier Universitaire Vaudois | 24 | 2006-06-01 | 2010-12-24 |
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Carcinoma, Non-Small-Cell Lung (5) · Head and Neck Neoplasms (5) · Lung Neoplasms (4) · Breast Neoplasms (3) · Carcinoma, Hepatocellular (3) · Melanoma (3) · Prostatic Neoplasms (3) · Squamous Cell Carcinoma of Head and Neck (3) · Brain Neoplasms (2) · Breast Neoplasms, Male (2) · Central Nervous System Neoplasms (2) · Liver Neoplasms (2) · Neoplasm Metastasis (2) · Neoplasms (2) · Sarcoma (2)
City of Hope Medical Center (3) · Memorial Sloan Kettering Cancer Center (3) · National Cancer Centre, Singapore (3) · Case Comprehensive Cancer Center (2) · National Cancer Institute (NCI) (2) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (2) · University of Nebraska (2) · Barbara Ann Karmanos Cancer Institute (1) · Centre Hospitalier Universitaire Vaudois (1) · Chao Family Comprehensive Cancer Center (1) · European Organisation for Research and Treatment of Cancer - EORTC (1) · Fred Hutchinson Cancer Center (1) · Greg Otterson (1) · Mayo Clinic (1) · University of California, Davis (1)
United States (20) · Singapore (3) · Belgium (1) · Switzerland (1)
Toh Han Chong, MD, MBBS, MRCP (2) · Angela Davies, MD (1) · Antonio Omuro, MD (1) · Aude Chapuis (1) · Charles M. Rudin, MD, PhD (1) · Donald Poon, MD (1) · Elizabeth C Reed, MD (1) · Francois Luthi, MD (1) · Gary G. Schwartz, MD, PhD, MPH (1) · Gregory A. Otterson, MD (1) · Jan B. Vermorken, MD, PhD (1) · Jeffrey A. Sosman, MD (1) · John Hoefs (1) · Kenneth H Cowan, MD, PhD (1) · Kian Fong Foo, MD (1)
PMID 17551310, PMID 18090584, PMID 20063546, PMID 21677464, PMID 23243055, PMID 26123189, PMID 26130251, PMID 27269940, PMID 28114604, PMID 31319977, PMID 35135810
P30CA006973 (2), P30CA008748 (2), P30CA033572 (2), P30CA036727 (2), K12CA076930 (1), N01CM17101 (1), N01CN35160 (1), P30CA012197 (1), P30CA015083 (1), P30CA022453 (1), R01CA138521 (1)