Immunoenzyme Techniques: Clinical Trials

31 trials of Immunoenzyme Techniques, newest first

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20 completed, 6 withdrawn, 4 terminated, 1 unknown. 31 Phase 1, 6 Phase 2.

By phase and status

PhaseTrialsStatus
Phase 131Completed 20, Withdrawn 6, Terminated 4, Unknown 1
Phase 26Completed 2, Terminated 2, Unknown 1, Withdrawn 1

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Trials (filtered) newest first · largest first

All 31 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Ex Vivo-Expanded HER2-Specific T Cells and Cyclophosphamide After Vaccine Therapy in Treating Patients With HER2-Positive Stage IV Breast Cancer
HER-2/neu peptide vaccine, cyclophosphamide, ex vivo-expanded HER2-specific T cells - HER2-positive Breast Cancer, Male Breast Cancer
Phase 1WithdrawnUniversity of Washington2012-06-012013-05-17
Vaccine Therapy in Treating Patients With Colorectal, Stomach, or Pancreatic Cancer
laboratory biomarker analysis, enzyme-linked immunosorbent assay, flow cytometry - Recurrent Colon Cancer, Recurrent Gastric Cancer
Phase 1CompletedCity of Hope Medical Center122011-12-222026-10-19
ABT-888, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
temozolomide, veliparib, DNA methylation analysis - Brain and Central Nervous System Tumors
Phase 1CompletedSidney Kimmel Comprehensive Cancer Center at Johns Hopkins242009-07-132018-06-27
Sorafenib, Epirubicin, Ifosfamide, and Radiation Therapy Followed By Surgery in Treating Patients With High-Risk Stage II or Stage III Soft Tissue Sarcoma
epirubicin hydrochloride, ifosfamide, sorafenib tosylate - Sarcoma
Phase 1CompletedOHSU Knight Cancer Institute182009-02-012018-09-07
Laboratory-Treated T Cells and Ipilimumab in Treating Patients With Metastatic Melanoma
ipilimumab, cyclophosphamide, biopsy - Recurrent Melanoma, Stage IV Melanoma
Phase 1 / Phase 2CompletedFred Hutchinson Cancer Center102009-02-012017-04-19
Stereotactic Radiosurgery and Erlotinib in Treating Patients With Non-Small Cell Lung Cancer and Brain Metastases
erlotinib hydrochloride, immunoenzyme technique, laboratory biomarker analysis - Lung Cancer, Metastatic Cancer
Phase 1WithdrawnUniversity of California, San Francisco2009-01-012012-10-04
Donor Stem Cell Transplant, Pentostatin, and Total-Body Irradiation in Treating Patients With Hematological Cancer
cyclosporine, mycophenolate mofetil, pentostatin - Chronic Myeloproliferative Disorders, Leukemia
Phase 1 / Phase 2WithdrawnUniversity of Nebraska2008-09-012023-08-14
Hydroxychloroquine and Temozolomide in Treating Patients With Metastatic or Unresectable Solid Tumors
hydroxychloroquine, temozolomide, TdT-mediated dUTP nick end labeling assay - Unspecified Adult Solid Tumor, Protocol Specific
Phase 1CompletedAbramson Cancer Center at Penn Medicine382008-06-012016-02-18
PEG-Interferon Alfa-2b and Sorafenib in Treating Patients With Unresectable or Metastatic Kidney Cancer
PEG-interferon alfa-2b, Sorafenib, gene expression analysis - Kidney Cancer
Phase 1TerminatedThomas Olencki12008-02-012015-06-08
Vandetanib and Temozolomide in Treating Patients With Advanced Solid Tumors That Cannot Be Removed By Surgery
temozolomide, vandetanib, immunoenzyme technique - Unspecified Adult Solid Tumor, Protocol Specific
Phase 1WithdrawnMayo Clinic2008-01-012014-03-10
Vaccine Therapy in Treating Patients With Recurrent B-Cell Lymphoma
plasmid DNA vaccine therapy, flow cytometry, immunoenzyme technique - Lymphoma
Phase 1CompletedMemorial Sloan Kettering Cancer Center82007-10-012015-11-17
KX2-391 in Treating Patients With Advanced Solid Tumors or Lymphoma That Did Not Respond to Treatment
Src kinase inhibitor KX2-391, immunoenzyme technique, pharmacological study - Lymphoma, Lymphoproliferative Disorder
Phase 1CompletedRoswell Park Cancer Institute72007-10-012011-03-02
SB939 in Treating Patients With Locally Advanced or Metastatic Solid Tumors
HDAC inhibitor SB939, immunoenzyme technique, immunohistochemistry staining method - Unspecified Adult Solid Tumor, Protocol Specific
Phase 1CompletedNCIC Clinical Trials Group392007-09-142023-08-04
Radiation Therapy and Ammonium Tetrathiomolybdate in Treating Patients With Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer
ammonium tetrathiomolybdate, immunoenzyme technique, laboratory biomarker analysis - Lung Cancer
Phase 1WithdrawnRoswell Park Cancer Institute2007-05-012022-10-03
Interleukin-7 in Treating Patients With Metastatic Melanoma or Locally Advanced or Metastatic Kidney Cancer
recombinant interleukin-7, gene expression analysis, polymerase chain reaction - Kidney Cancer, Melanoma (Skin)
Phase 1TerminatedCytheris SA92007-05-012012-10-18
Defined Green Tea Catechins in Treating Patients With Prostate Cancer Undergoing Surgery to Remove the Prostate
defined green tea catechin extract, placebo, immunohistochemistry staining method - Adenocarcinoma of the Prostate, Stage I Prostate Cancer
Phase 1CompletedNational Cancer Institute (NCI)502007-03-012014-10-08
Studying Genes in Blood and Lung Fluid Samples From Patients With Chronic Obstructive Pulmonary Disease With or Without a Previous Diagnosis of Lung Cancer or With Asthma Treated With Budesonide and Formoterol
budesonide/formoterol fumarate dihydrate inhalation aerosol, DNA methylation analysis, comparative genomic hybridization - Lung Cancer, Precancerous Condition
Phase 1CompletedBritish Columbia Cancer Agency302007-01-012012-03-09
Vaccine Therapy and GM-CSF in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndromes, Non-Small Cell Lung Cancer, or Mesothelioma
WT-1 analog peptide vaccine, incomplete Freund's adjuvant, sargramostim - Leukemia, Lung Cancer
Phase 1CompletedMemorial Sloan Kettering Cancer Center222006-10-012016-03-02
AEG35156 and Docetaxel in Treating Patients With Locally Advanced, Metastatic, or Recurrent Solid Tumors
AEG35156, docetaxel, protein expression analysis - Unspecified Adult Solid Tumor, Protocol Specific
Phase 1CompletedNCIC Clinical Trials Group272006-07-272023-08-04
Vaccine Therapy, Incomplete Freund's Adjuvant, and GM-CSF in Treating Patients With HIV
E1M184V peptide vaccine, incomplete Freund's adjuvant, sargramostim - Nonneoplastic Condition
Phase 1CompletedNational Institutes of Health Clinical Center (CC)402006-07-012012-05-02

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Conditions studied

Carcinoma, Non-Small-Cell Lung (6)  ·  Lung Neoplasms (6)  ·  Breast Neoplasms (4)  ·  Lymphoma, B-Cell, Marginal Zone (4)  ·  Lymphoma, Follicular (4)  ·  Lymphoma, Mantle-Cell (4)  ·  Lymphoma, Non-Hodgkin (4)  ·  Melanoma (4)  ·  Carcinoma, Ovarian Epithelial (3)  ·  Congenital Abnormalities (3)  ·  Leukemia, Lymphocytic, Chronic, B-Cell (3)  ·  Lymphoma (3)  ·  Lymphoma, Large B-Cell, Diffuse (3)  ·  Precursor Cell Lymphoblastic Leukemia-Lymphoma (3)  ·  Blast Crisis (2)

Sponsors

City of Hope Medical Center (3)  ·  University of Washington (3)  ·  Mayo Clinic (2)  ·  Memorial Sloan Kettering Cancer Center (2)  ·  NCIC Clinical Trials Group (2)  ·  Roswell Park Cancer Institute (2)  ·  University of California, Davis (2)  ·  Abramson Cancer Center at Penn Medicine (1)  ·  British Columbia Cancer Agency (1)  ·  Case Comprehensive Cancer Center (1)  ·  Centre Hospitalier Universitaire Vaudois (1)  ·  Cytheris SA (1)  ·  Fred Hutchinson Cancer Center (1)  ·  National Cancer Institute (NCI) (1)  ·  National Institutes of Health Clinical Center (CC) (1)

Countries

United States (23)  ·  Canada (3)  ·  Switzerland (1)

Top investigators

Angela Davies, MD (2)  ·  Alan N. Houghton, MD (1)  ·  Alex A. Adjei, MD, PhD (1)  ·  Andrew D. Zelenetz, MD, PhD (1)  ·  Aude Chapuis (1)  ·  Christopher W. Ryan, MD (1)  ·  Claire F. Verschraegen, MD (1)  ·  Francois Luthi, MD (1)  ·  Frederick Ahmann (1)  ·  Gerald Batist, MD (1)  ·  Hillard M. Lazarus, MD (1)  ·  James L. Rubenstein, MD, PhD (1)  ·  Jeffrey A. Sosman, MD (1)  ·  Kathleen M. Wyvill, BSN, RN (1)  ·  Larry Kleinberg, MD (1)

Results publications

PMID 18090584, PMID 20400682, PMID 21285985, PMID 22044694, PMID 24386300, PMID 24987057, PMID 27269940, PMID 28679643, PMID 36326756

NIH funding

K12CA076930 (1), N01CN35158 (1), P01CA023766 (1), P30CA008748 (1), P30CA015083 (1), P30CA033572 (1), P30CA036727 (1), P30CA043703 (1), P30CA069533 (1), P30CA093373 (1), U01CA062475 (1)