22 completed, 16 unknown, 9 terminated, 5 recruiting. 25 Phase 2, 15 Not applicable, 11 Phase 3, 8 Phase 1, 4 Phase 4.
Follow Hyperbaric oxygen: new trials by email Literature Review of Hyperbaric oxygen trials Research Report on Hyperbaric oxygen
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Long-Term Outcomes Following HBOT Hyperbaric Oxygen Therapy (HBOT) - Traumatic Brain Injury, Post-Concussive Symptoms | Phase 2 | Recruiting | Summit Hyperbarics and Wellness | 35 | 2026-06-18 | 2026-07-28 |
| Hyperbaric Oxygen Therapy in HAMstring Injury (HOTHAM) Trial Hyperbaric oxygen - Hamstring Injury | Phase 3 | Recruiting | JL Tol | 50 | 2024-10-30 | 2024-11-20 |
| Treatment of Post-COVID-19 With Hyperbaric Oxygen Therapy: a Randomized, Controlled Trial Hyperbaric oxygen - Post-COVID-19 Syndrome, Post-COVID Syndrome | Phase 3 | Unknown | Erasmus Medical Center | 120 | 2024-10-01 | 2024-02-28 |
| Hyperbaric Oxygen Therapy for Post-COVID-19 Syndrome Hyperbaric oxygen, Sham - Covid19, Neurocognitive Dysfunction | Not applicable | Recruiting | Assaf-Harofeh Medical Center | 91 | 2023-06-01 | 2026-04-21 |
| Hyperbaric Oxygen Therapy for Optic Neuropathies Hyperbaric Oxygen, Sham Hyperbaric Oxygen - Optic Neuropathy, Glaucoma | Not applicable | Recruiting | Stanford University | 60 | 2022-11-01 | 2026-10-09 |
| Effects of HBO on Glucose in Patients With DM Hyperbaric Oxygen - Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1 | Not applicable | Terminated | Legacy Health System | 6 | 2022-09-02 | 2026-08-26 |
| Hyperbaric Oxygen Therapy for Pyoderma Gangrenosum Hyperbaric oxygen, Control group - Pyoderma Gangrenosum | Phase 3 | Terminated | Erasmus Medical Center | 3 | 2022-06-01 | 2024-09-19 |
| Repeated HBO Therapy in Myeloma Patients Undergoing High-Dose Therapy and Auto-HCT Hyperbaric oxygen - Myeloma | Early Phase 1 | Completed | University of Rochester | 29 | 2022-04-22 | 2025-09-10 |
| Hyperbaric Oxygen Therapy Compared to Cognitive Training in FASD Hyperbaric Oxygen, Cognitive training - FASD | Not applicable | Withdrawn | Assaf-Harofeh Medical Center | 2021-10-20 | 2026-05-13 | |
| Does Increasing Oxygen Nurture Your Symptomatic Ischemic Ulcer Sufficiently? Hyperbaric oxygen - Peripheral Vascular Disease, Diabetic Foot Ulcer | Phase 4 | Active not recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 30 | 2021-10-08 | 2024-11-08 |
| Safety and Efficacy of Hyperbaric Oxygen Therapy for Long COVID Syndrome Hyperbaric oxygen, Sham treatment - COVID-19, Post COVID-19 Condition | Phase 2 | Completed | Karolinska University Hospital | 80 | 2021-09-15 | 2024-08-22 |
| Inner and Middle Ear Effects of Hyperbaric Oxygen Thrapy Hyperbaric oxygen - Otitic Barotrauma | Unknown | Assiut University | 30 | 2021-04-01 | 2020-07-09 | |
| Hyperbaric Oxygen and Outcome After Below Knee Amputations Hyperbaric Oxygen - Amputation; Postoperative, Sequelae | Phase 1 / Phase 2 | Terminated | Duke University | 4 | 2021-01-01 | 2025-08-11 |
| Hyperbaric Oxygen as an Adjuvant Treatment for Patients With Covid-19 Severe Hypoxemia Hyperbaric Oxygen - Covid19 | Phase 2 | Terminated | Asociación Argentina de Medicina Hiperbárica e Investigación | 40 | 2020-07-06 | 2021-01-15 |
| Hyperbaric Oxygen Therapy and Allogeneic Peripheral Blood Stem Cell (PBSC) Transplant Hyperbaric oxygen - Acute Myeloid Leukemia, Myelodysplastic Syndromes | Early Phase 1 | Recruiting | Omar Aljitawi | 24 | 2020-07-01 | 2026-06-03 |
| Safety and Efficacy of Hyperbaric Oxygen for ARDS in Patients With COVID-19 Hyperbaric oxygen - SARS (Severe Acute Respiratory Syndrome), Cytokine Storm | Phase 2 / Phase 3 | Terminated | Karolinska Institutet | 34 | 2020-06-03 | 2023-01-09 |
| Hyperbaric Oxygen Therapy After Stroke - PILOT Hyperbaric oxygen - Cerebral Stroke | Phase 2 | Withdrawn | Norwegian Underwater Intervention (NUI) | 2020-04-20 | 2020-04-27 | |
| Hyperbaric Oxygenation in Diabetic Ulcer Hyperbaric oxygen - Diabetes Mellitus | Phase 3 | Unknown | Medical University of Graz | 80 | 2019-12-01 | 2019-05-20 |
| Hyperbaric Oxygen Treatment in Humans With Gram Positive Cocci Endocarditis Hyperbaric oxygen - Infectious Endocarditis | Phase 2 | Unknown | Ole Hyldegaard | 10 | 2019-12-01 | 2020-12-31 |
| Hyperbaric Radiation Sensitization of Head and Neck Cancers Hyperbaric oxygen, Hyperbaric chamber - Squamous Cell Carcinoma of the Head and Neck | Phase 2 | Unknown | National Baromedical Services | 400 | 2019-07-01 | 2019-02-18 |
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Brain Injuries, Traumatic (5) · Stroke (5) · COVID-19 (4) · Post-Concussion Syndrome (4) · Brain Concussion (2) · Brain Injury, Chronic (2) · Carbon Monoxide Poisoning (2) · Central Nervous System Neoplasms (2) · Diabetes Mellitus (2) · Fibromyalgia (2) · Hyperalgesia (2) · Inflammation (2) · Myelodysplastic Syndromes (2) · Osteoradionecrosis (2) · Post-Acute COVID-19 Syndrome (2)
Assaf-Harofeh Medical Center (6) · Duke University (4) · Barrett Cancer Center (2) · Erasmus Medical Center (2) · Intermountain Health Care, Inc. (2) · Lone Forner (2) · National Baromedical Services (2) · University of Rochester (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Asociación Argentina de Medicina Hiperbárica e Investigación (1) · Assiut University (1) · Bayside Health (1) · Copenhagen University Hospital, Rigshospitalet (1) · Dartmouth-Hitchcock Medical Center (1) · David Grant U.S. Air Force Medical Center (1)
United States (24) · Denmark (6) · Israel (6) · Netherlands (5) · Sweden (5) · Canada (3) · United Kingdom (3) · Austria (2) · China (2) · Egypt (2) · Germany (2) · Norway (2) · Argentina (1) · Australia (1) · Chile (1)
Lindell K Weaver, MD (2) · Lone Forner, DDS, PhD (2) · Peter Lindholm, MD, PhD (2) · Anders Kjellberg, MD (1) · Anders Kjellberg, MD, PhD (1) · Ara A. Chalian, MD (1) · Corey A Siegel, MD, MS (1) · David W Harrison, MD,CCFP(EM),FRCPC (1) · Dick Clarke, CHT (1) · E. George Wolf, M.D. (1) · Enas S Mohamed, Professor (1) · Enoch Huang, MD (1) · Errol Prens, Prof.Dr. (1) · Fabrizio Verdini, MD (1)
PMID 12577851, PMID 16457083, PMID 16510383, PMID 19949909, PMID 20129356, PMID 20954243, PMID 22513920, PMID 23335971, PMID 23863187, PMID 23992903, PMID 24471697, PMID 25401463, PMID 26010952, PMID 26650550, PMID 28357821, PMID 30402285, PMID 31394602, PMID 31394603, PMID 31537473, PMID 31916854, PMID 32189664, PMID 32947434, PMID 33518452, PMID 34226219, PMID 35866376, PMID 36670365, PMID 37230523, PMID 37301934, PMID 37510965, PMID 39393522, PMID 40228859, PMID 40291346
2017 (1), 2019 (1), R37CA225791 (1)