45 completed. 45 Phase 3, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 45 | Completed 45 |
| Phase 2 | 4 | Completed 4 |
Follow Hydroxychloroquine: new trials by email Literature Review of Hydroxychloroquine trials Research Report on Hydroxychloroquine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Trial For Early SARS-CoV-2 (COVID-19) Treatment Hydroxychloroquine, Favipiravir, Favipiravir + Hydroxychloroquine - Covid19 | Phase 3 | Completed | Health Institutes of Turkey | 1120 | 2020-11-16 | 2021-07-29 |
| Remdesivir Efficacy In Management Of COVID-19 Patients Remdesivir, Standard of care_1, Standard of care_2 - Covid19 | Phase 3 | Completed | Ain Shams University | 77 | 2020-07-27 | 2021-04-22 |
| Prevention of Complications (SARS-CoV-2): Clinical Study Control group (standard hospital treatment), Group Hydroxychloroquine, Group Hydroxychloroquine and apixaban - Complication | Phase 3 | Completed | Universidade do Vale do Sapucai | 176 | 2020-07-01 | 2021-03-09 |
| Hydroxychloroquine to Prevent SARS-CoV-2 Infection/COVID-19 Hydroxychloroquine - SARS-CoV-2 | Phase 3 | Completed | Universidad Peruana Cayetano Heredia | 68 | 2020-06-25 | 2021-10-28 |
| Zinc With Chloroquine/Hydroxychloroquine in Treatment of COVID-19 Chloroquine or hydroxychloroquine, zinc - COVID | Phase 3 | Completed | Tanta University | 191 | 2020-06-23 | 2022-04-01 |
| A Preventive Treatment for Migrant Workers at High-risk of COVID-19 Hydroxychloroquine Sulfate Tablets, Ivermectin 3mg Tab, Zinc - Covid-19 | Phase 3 | Completed | National University Hospital, Singapore | 4257 | 2020-05-13 | 2020-10-19 |
| Hydroxychloroquine Efficacy and Safety in Preventing SARS-CoV-2 Infection and COVID-19 Disease Severity During Pregnancy and Postpartum Hydroxychloroquine, Placebo - Pregnancy Related, COVID | Phase 3 | Completed | Barcelona Institute for Global Health | 129 | 2020-05-13 | 2022-01-12 |
| Ivermectin for Severe COVID-19 Management Ivermectin - COVID-19 | Phase 3 | Completed | Afyonkarahisar Health Sciences University | 66 | 2020-05-11 | 2021-01-27 |
| Hydroxychloroquine and Ivermectin for the Treatment of COVID-19 Infection Hydroxychloroquine, Ivermectin, Placebo - COVID-19 | Phase 3 | Completed | Centenario Hospital Miguel Hidalgo | 108 | 2020-05-04 | 2020-11-09 |
| Hydroxychloroquine, Oseltamivir and Azithromycin for the Treatment of COVID-19 Infection: An RCT Hydroxychloroquine, Oseltamivir, Azithromycin - COVID 19 | Phase 3 | Completed | Shehnoor Azhar | 550 | 2020-04-22 | 2022-02-10 |
| Healthcare Worker Exposure Response and Outcomes of Hydroxychloroquine Hydroxychloroquine, Placebo oral tablet - COVID-19 | Phase 3 | Completed | Adrian Hernandez | 1360 | 2020-04-22 | 2021-10-12 |
| Prevention of SARS-CoV-2 in Hospital Workers s Exposed to the Virus hydroxychloroquine, azithromycin, hydroxychloroquine placebo - SARS-CoV-2 Infection | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 122 | 2020-04-17 | 2025-11-20 |
| Efficacy of Chloroquine or Hydroxychloroquine in Treating Pneumonia Caused by SARS-Cov-2 - COVID-19 Chloroquine, Hydroxychloroquine, standard care - COVID, COVID-19 | Phase 3 | Completed | Centro de Estudos e Pesquisa em Emergencias Medicas e Terapia Intensiva | 142 | 2020-04-16 | 2021-05-12 |
| Randomized Clinical Trial for the Prevention of SARS-CoV-2 Infection (COVID-19) in Healthcare Personnel Emtricitabine/tenofovir disoproxil, Hydroxychloroquine, Placebo: Emtricitabine/tenofovir disoproxil Placebo - Coronavirus Infection | Phase 3 | Completed | Plan Nacional sobre el Sida (PNS) | 1002 | 2020-04-15 | 2021-09-16 |
| Efficacy of Sofosbuvir Plus Ledipasvir in Egyptian Patients With COVID-19 Compared to Standard Treatment Sofosbuvir plus Ledipasvir - Covid19 | Phase 3 | Completed | Almaza Military Fever Hospital | 250 | 2020-04-15 | 2020-08-28 |
| Hydroxychloroquine Treatment for Severe COVID-19 Pulmonary Infection (HYDRA Trial) Hydroxychloroquine, Placebo oral tablet - COVID-19, Severe Acute Respiratory Syndrome | Phase 3 | Completed | National Institute of Respiratory Diseases, Mexico | 320 | 2020-04-14 | 2022-02-01 |
| Hydroxychloroquine Chemoprophylaxis in Healthcare Personnel in Contact With COVID-19 Patients (PHYDRA Trial) Hydroxychloroquine, Placebo oral tablet - COVID-19, Severe Acute Respiratory Syndrome | Phase 3 | Completed | National Institute of Respiratory Diseases, Mexico | 289 | 2020-04-14 | 2022-02-01 |
| The Fleming [FMTVDM] Directed CoVid-19 Treatment Protocol Hydroxychloroquine, Azithromycin, Hydroxychloroquine, Doxycycline, Hydroxychloroquine, Clindamycin - CoVid 19 Positive | Phase 2 / Phase 3 | Completed | The Camelot Foundation | 1800 | 2020-04-11 | 2020-11-12 |
| Clearing the Fog: Is Hydroxychloroquine Effective in Reducing COVID-19 Progression HCQ - Covid19, Progression | Phase 3 | Completed | UNICEF | 540 | 2020-04-10 | 2020-08-21 |
| A Study of the Effectiveness of an Off Label Mefloquine Use for the Treatment of Patients With COVID19 Mefloquine, Hydroxychloroquine, Mefloquine + azithromycin + / - tocilizumab - Pneumonia, Viral, Respiratory Failure | Phase 2 / Phase 3 | Completed | Burnasyan Federal Medical Biophysical Center | 320 | 2020-04-08 | 2021-01-27 |
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COVID-19 (25) · Coronavirus Infections (13) · Arthritis, Rheumatoid (6) · Severe Acute Respiratory Syndrome (6) · Pneumonia, Viral (3) · Respiratory Distress Syndrome (3) · Pneumonia (2) · Acute Lung Injury (1) · Autoimmune Diseases (1) · Coronaviridae Infections (1) · Disease Progression (1) · Dry Eye Syndromes (1) · Giant Cell Arteritis (1) · Graft vs Host Disease (1) · Insulin Resistance (1)
Sanofi (4) · Assistance Publique - Hôpitaux de Paris (2) · Barcelona Institute for Global Health (2) · National Institute of Respiratory Diseases, Mexico (2) · Tanta University (2) · University of Minnesota (2) · Adrian Hernandez (1) · Afyonkarahisar Health Sciences University (1) · Ain Shams University (1) · All India Institute of Medical Sciences (1) · Almaza Military Fever Hospital (1) · Brigham and Women's Hospital (1) · Burnasyan Federal Medical Biophysical Center (1) · Centenario Hospital Miguel Hidalgo (1) · Centro de Estudos e Pesquisa em Emergencias Medicas e Terapia Intensiva (1)
United States (12) · Brazil (6) · Mexico (6) · Spain (5) · Egypt (4) · France (4) · Russia (4) · Canada (3) · Greece (3) · Italy (3) · Poland (3) · Turkey (Türkiye) (3) · Argentina (2) · Australia (2) · Austria (2)
Adrian Hernandez, MD (1) · Alberto Pesci (1) · Alejandro Llanos, MD, PhD (1) · Alexandre Biasi, PhD (1) · Andrew L. Gilman, MD (1) · Boyd Taylor Thompson, MD (1)
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R21AR057924 (1)