5 completed, 2 terminated. 4 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 2, Terminated 2 |
| Phase 3 | 2 | Completed 2 |
| Phase 1 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Healthcare Worker Exposure Response and Outcomes of Hydroxychloroquine Hydroxychloroquine, Placebo oral tablet - COVID-19 | Phase 3 | Completed | Adrian Hernandez | 1360 | 2020-04-22 | 2021-10-12 |
| Subcutaneous Furosemide in Acute Decompensated Heart Failure: The SUBQ-HF Study subcutaneous furosemide and sc2wear device - Acute Heart Failure, Decompensated Heart Failure | Phase 2 | Terminated | Adrian Hernandez | 11 | 2018-04-27 | 2019-01-23 |
| Subcutaneous Furosemide in Acute Decompensated Heart Failure Pilot Furosemide - Acute Heart Failure | Phase 1 | Completed | Adrian Hernandez | 40 | 2016-12-19 | 2019-03-15 |
| Inorganic Nitrite Delivery to Improve Exercise Capacity in HFpEF Nebulized Sodium Nitrite, Placebo - Heart Failure | Phase 2 | Completed | Adrian Hernandez | 105 | 2016-08-10 | 2019-03-13 |
| Oral Iron Repletion Effects On Oxygen Uptake in Heart Failure Polysaccharide Iron Complex 150 mg, Placebo (for Polysaccharide Iron Complex) - Chronic Heart Failure | Phase 3 | Completed | Adrian Hernandez | 225 | 2014-09-03 | 2017-07-11 |
| Nitrate's Effect on Activity Tolerance in Heart Failure With Preserved Ejection Fraction Isosorbide Mononitrate, Placebo - Heart Failure | Phase 2 | Completed | Adrian Hernandez | 110 | 2014-04-01 | 2016-11-28 |
| Study of Renal Denervation in Patients With Heart Failure Symplicity Renal Denervation - Heart Failure | Phase 2 | Terminated | Adrian Hernandez | 5 | 2013-12-01 | 2016-02-02 |
Heart Failure (3) · Acute Lung Injury (1) · COVID-19 (1) · Coronaviridae Infections (1) · Coronavirus Infections (1) · Lung Diseases (1) · Lung Injury (1) · Nidovirales Infections (1) · RNA Virus Infections (1) · Respiration Disorders (1) · Respiratory Distress Syndrome (1) · Respiratory Tract Diseases (1) · Respiratory Tract Infections (1) · Severe Acute Respiratory Syndrome (1) · Virus Diseases (1)
Furosemide (1) · Hydroxychloroquine (1) · Niferex (1) · isosorbide-5-mononitrate (1)
United States (7)
Eugene Braunwald, MD (5) · Kevin Anstrom, PhD (1) · Kevin Hernandez, MD (1)
PMID 32150314, PMID 26549714, PMID 27140203, PMID 28476756, PMID 28510680, PMID 28588021, PMID 30398602, PMID 36682681
U10HL084904 (4)