8 completed, 3 terminated, 2 unknown, 1 active not recruiting. 16 Phase 2, 4 Phase 3, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 16 | Completed 8, Terminated 3, Unknown 2, Active not recruiting 1, Recruiting 1, Withdrawn 1 |
| Phase 3 | 4 | Completed 3, Unknown 1 |
| Phase 1 | 2 | Completed 1, Withdrawn 1 |
Follow hydrocortisone hemisuccinate: new trials by email Literature Review of hydrocortisone hemisuccinate trials Research Report on hydrocortisone hemisuccinate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia Biospecimen Collection, Bone Marrow Aspiration, Calaspargase Pegol - Recurrent Acute Leukemia of Ambiguous Lineage, Recurrent Acute Lymphoblastic Leukemia | Phase 2 | Active not recruiting | Children's Oncology Group | 78 | 2024-01-08 | 2026-08-25 |
| A Study of the Drug IMGN632 in Children With Leukemia That Has Come Back After Treatment or is Difficult to Treat Anti-CD123 ADC IMGN632, Bone Marrow Aspiration and Biopsy, Cytarabine - Recurrent Acute Myeloid Leukemia, Recurrent B Acute Lymphoblastic Leukemia | Phase 1 / Phase 2 | Withdrawn | Children's Oncology Group | 2023-08-01 | 2023-09-01 | |
| Corticosteroid Intralesional Injection as an Alternative Treatment in Oral Pyogenic Granuloma in the Esthetic Zone. Solu-Cortef - Oral Pyogenic Granuloma | Phase 2 / Phase 3 | Unknown | Beni-Suef University | 30 | 2022-05-01 | 2022-09-14 |
| A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL) 3-Dimensional Conformal Radiation Therapy, Asparaginase Erwinia chrysanthemi, Biospecimen Collection - Down Syndrome, Recurrent B Acute Lymphoblastic Leukemia | Phase 2 | Recruiting | National Cancer Institute (NCI) | 461 | 2020-12-17 | 2026-09-01 |
| Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement Azacitidine, Biospecimen Collection, Computed Tomography - Acute Leukemia of Ambiguous Lineage, B Acute Lymphoblastic Leukemia | Phase 2 | Completed | National Cancer Institute (NCI) | 78 | 2017-04-01 | 2025-02-27 |
| Hydrocortisone Treatment In Systemic Low Blood Pressure During Hypothermia in Asphyxiated Newborns Hydrocortisone, Placebo - Hypoxic-Ischemic Encephalopathy, Asphyxia | Phase 2 / Phase 3 | Completed | Semmelweis University | 32 | 2016-02-01 | 2023-04-21 |
| Treatment of Apomorphine-induced Skin Reactions: a Pilot Study Apomorphine 0.25% (2.5mg/ml), Massage with a spiky ball, Hydrocortisone cream 1% - Parkinson's Disease, Apomorphine-induced Skin Reactions | Phase 2 | Terminated | University Medical Center Groningen | 13 | 2015-06-01 | 2024-03-13 |
| Ultradian Subcutaneous Hydrocortisone Infusion in Addison Disease and Congenital Adrenal Hyperplasia Solu-Cortef, Cortef - Addison Disease, Adrenal Hyperplasia Congenital | Phase 1 / Phase 2 | Completed | Haukeland University Hospital | 8 | 2014-03-27 | 2024-06-07 |
| Chemotherapy With Liposomal Cytarabine CNS Prophylaxis for Adult Acute Lymphoblastic Leukemia & Lymphoblastic Lymphoma DNR, VCR, PEG-asp - Acute Lymphocytic Leukemia, Adult Lymphoblastic Lymphoma | Phase 2 | Terminated | University of California, San Diego | 31 | 2014-01-01 | 2022-05-02 |
| Continuous Subcutaneous Hydrocortisone Infusion In Addison's Disease and Type 1 Diabetes Cortef, Solu-cortef - Addison Disease, Type 1 Diabetes | Phase 2 | Terminated | Haukeland University Hospital | 4 | 2013-04-24 | 2024-03-01 |
| Continuous Subcutaneous Hydrocortisone Infusion in Congenital Adrenal Hyperplasia Hydrocortisone, Cortisone acetate - Adrenal Hyperplasia, Congenital | Phase 2 | Unknown | Haukeland University Hospital | 20 | 2013-02-01 | 2016-12-21 |
| Glucocorticoid Treatment in Addison's Disease Solu-Cortef (hydrocortisone), Cortef (hydrocortisone) - Addison's Disease | Phase 2 / Phase 3 | Completed | Haukeland University Hospital | 33 | 2010-02-01 | 2013-03-20 |
| Dasatinib and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Asparaginase, Cyclophosphamide, Cytarabine - Acute Lymphoblastic Leukemia, Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 | Phase 2 / Phase 3 | Completed | National Cancer Institute (NCI) | 63 | 2008-07-14 | 2020-04-13 |
| Evaluation of Corticosteroid Therapy in Childhood Severe Sepsis - a Randomised Pilot Study hydrocortisone - Sepsis | Phase 2 | Completed | University Hospital Southampton NHS Foundation Trust | 21 | 2008-04-01 | 2016-05-06 |
| Intrapleural Methylprednisolone Injection for Multiple Organ Failure With Acute Respiratory Distress Syndrome conventional ECMO with intravenous steroid, solumedrol - Acute Respiratory Distress Syndrome (ARDS), Multiple Organ Failure | Phase 2 | Completed | National Taiwan University Hospital | 29 | 2005-06-01 | 2011-08-26 |
| Rituximab, Rasburicase, and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Advanced B-Cell Leukemia or Lymphoma doxorubicin hydrochloride, cyclophosphamide, methotrexate - Childhood Burkitt Lymphoma, Childhood Diffuse Large Cell Lymphoma | Phase 2 | Completed | Children's Oncology Group | 97 | 2004-06-01 | 2014-09-19 |
Burkitt Lymphoma (4) · Addison Disease (3) · Leukemia, Biphenotypic, Acute (3) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (3) · Adrenal Hyperplasia, Congenital (2) · Asphyxia (1) · Dendritic Cell Sarcoma, Interdigitating (1) · Diabetes Mellitus, Type 1 (1) · Down Syndrome (1) · Hypoxia-Ischemia, Brain (1) · Leukemia, Myeloid, Acute (1) · Lymphoma, Large B-Cell, Diffuse (1) · Multiple Organ Failure (1) · Parkinson Disease (1) · Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (1)
Haukeland University Hospital (4) · Children's Oncology Group (3) · National Cancer Institute (NCI) (3) · Beni-Suef University (1) · National Taiwan University Hospital (1) · Semmelweis University (1) · University Hospital Southampton NHS Foundation Trust (1) · University Medical Center Groningen (1) · University of California, San Diego (1)
United States (6) · Canada (4) · Norway (4) · Australia (3) · Puerto Rico (3) · Egypt (1) · Hungary (1) · Netherlands (1) · New Zealand (1) · Sweden (1) · Taiwan (1) · United Kingdom (1)
Andrew Wolf, MBBChir MD (1) · Carrol Gamble, PhD (1) · Diana M Gibb, MBChB MD (1) · Eman Magdy, PhD (1) · James K Mangan, MD, PhD (1) · John V Pappachan, MB BChir (1) · Katerina Simunkova, MD, PhD (1) · Katerina Simunkova, PhD (1) · Kelly E Faulk (1) · Matthew A Kutny (1) · Michael Levin, MBBCH PhD (1) · Mitchell Cairo, MD CCRP (1)
PMID 12011123, PMID 29812996, PMID 30117142, PMID 31155392, PMID 33242441, PMID 34218046, PMID 35622074, PMID 37172949, PMID 38867582, PMID 40983658, PMID 41671463
U10CA180886 (4), U10CA098543 (2), 2009 (1)