56 completed, 9 unknown, 8 recruiting, 6 terminated. 88 Phase 3, 13 Phase 2.
Follow Hydrocortisone: new trials by email Literature Review of Hydrocortisone trials Research Report on Hydrocortisone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing the Addition of Daratumumab to Chemotherapy for Treating Patients With Newly-Diagnosed T-Cell Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LL) Biopsy Procedure, Biospecimen Collection, Bone Marrow Aspiration - Stage II T Lymphoblastic Leukemia/Lymphoma, Stage III T Lymphoblastic Leukemia/Lymphoma | Phase 2 / Phase 3 | Not yet recruiting | Children's Oncology Group | 1708 | 2026-08-28 | 2026-07-30 |
| Hydrocortisone Plus Fludrocortisone in High-risk Patients Undergoing for Cardiac Surgery hydrocortisone plus fludrocortisone, placebo of hydrocortisone plus fludrocortisone - Inflammation in Cardiac Surgery | Phase 3 | Recruiting | Centre Hospitalier Universitaire, Amiens | 196 | 2025-04-30 | 2026-06-03 |
| A Comparative Study of Glucocorticoids Efficacy in Acute Respiratory Distress Syndrome Methylprednisolone, Dexamethasone, Hydrocortisone - Acute Respiratory Distress Syndrome | Phase 2 / Phase 3 | Completed | Fayoum University | 195 | 2024-08-01 | 2026-09-01 |
| Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003) Opevesostat, Abiraterone acetate, Enzalutamide - Prostate Cancer Metastatic | Phase 3 | Recruiting | Merck Sharp & Dohme LLC | 1310 | 2023-12-31 | 2026-11-05 |
| A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004) Opevesostat, Dexamethasone, Fludrocortisone acetate - Metastatic Castration-resistant Prostate Cancer (mCRPC), Prostatic Neoplasms | Phase 3 | Recruiting | Merck Sharp & Dohme LLC | 1314 | 2023-12-18 | 2026-10-20 |
| Comparison of Topical Treatment for Inflammatory Secretions of the Conjonctiva (Patients With Ocular Prostheses) Hydrocortisone, Dexamethasone, Povidone - Ocular Inflammation, Ocular Prostheses | Phase 3 | Recruiting | Agnes | 30 | 2023-05-12 | 2025-08-15 |
| Comparison of Chronocort Versus Standard Hydrocortisone Replacement Therapy in Participants Aged 16 Years and Over With Congenital Adrenal Hyperplasia Chronocort, Cortef, Placebo - Congenital Adrenal Hyperplasia | Phase 3 | Completed | Neurocrine UK Limited | 55 | 2022-05-24 | 2026-10-02 |
| Corticosteroid Intralesional Injection as an Alternative Treatment in Oral Pyogenic Granuloma in the Esthetic Zone. Solu-Cortef - Oral Pyogenic Granuloma | Phase 2 / Phase 3 | Unknown | Beni-Suef University | 30 | 2022-05-01 | 2022-09-14 |
| VAsopressin and STeroids in Addition to Adrenaline in Cardiac Arrest - a Randomized Clinical Trial Vasopressin; Methylprednisolone; Hydrocortisone, Sodium chloride - Cardiac Arrest;In-hospital Cardiac Arrest; Methylprednisolone; Vasopressin; Adrenaline; Randomized Clinical Trial | Phase 3 | Recruiting | Tiohundra AB | 1276 | 2021-11-17 | 2022-01-20 |
| Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Vitamin C, Placebo - Sepsis, Septic Shock | Phase 3 | Terminated | Hospital Sirio-Libanes | 71 | 2021-08-01 | 2024-01-30 |
| Hydrocortisone Treatment for Symmetric Lipomatosis Associated With Neuropathy (SLN): an N-of-1 Study Hydrocortisone Treatment for Symmetric Lipomatosis Associated With Neuropathy (SLN): an N-of-1 Study Hydrocortisone, Placebo - Symmetric Lipomatoses, Multiple | Phase 3 | Unknown | Erasmus Medical Center | 1 | 2021-06-01 | 2021-03-29 |
| A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations Allogeneic Hematopoietic Stem Cell Transplantation, Asparaginase Erwinia chrysanthemi, Biospecimen Collection - Acute Myeloid Leukemia | Phase 3 | Recruiting | Children's Oncology Group | 1400 | 2020-07-21 | 2026-09-17 |
| Efficacy and Safety of Corticosteroids in Oxygen-dependent Patients With COVID-19 Pneumonia Prednisone, Hydrocortisone - COVID-19 | Phase 3 | Withdrawn | University Hospital, Tours | 2020-07-03 | 2026-06-15 | |
| Hydrocortisone for COVID-19 and Severe Hypoxia Hydrocortisone, Sodium Chloride 9mg/mL - Covid-19, Hypoxia | Phase 3 | Completed | Scandinavian Critical Care Trials Group | 30 | 2020-04-17 | 2021-09-21 |
| Low Dose Corticosteroid Infusion in Vasoplegia After Cardiac Surgery (CORTIVAS-CS) hydrocortisone sodium succinate, Saline - Vasoplegia, Cardiac Surgery | Phase 3 | Unknown | Instituto do Coracao | 140 | 2020-03-01 | 2020-03-10 |
| Post-operative Corticosteroid Treatment After Mitral Valve Surgery Hydrocortisone, Placebos - Atrial Fibrillation | Phase 2 / Phase 3 | Withdrawn | Kuopio University Hospital | 2020-01-01 | 2022-04-07 | |
| Vitamin C, Thiamine, Cyanocobalamine, Pyridoxine and Hydrocortisone in Sepsis Vitamin C, Hydrocortisone, Complex B - Sepsis, Septic Shock | Phase 3 | Completed | IMSS Hospital General de Zona 11, Piedras Negras | 19 | 2019-09-01 | 2020-10-19 |
| Safety and Efficacy of Prednisolone in Adrenal Insufficiency Disease (PRED-AID Study) Prednisolone, Hydrocortisone - Adrenal Insufficiency | Phase 3 | Unknown | Imperial College London | 44 | 2019-07-31 | 2023-09-01 |
| Low Dose of Hydrocortisone and Fludrocortisone in Adult Cardiogenic Shock. Hydrocortisone + Flucortac, Placebo - Cardiogenic Shock | Phase 3 | Completed | CMC Ambroise Paré | 380 | 2019-04-19 | 2026-05-19 |
| Stress Hydrocortisone In Pediatric Septic Shock Hydrocortisone, sodium succinate, Normal saline - Septic Shock | Phase 3 | Recruiting | Jerry Zimmerman | 500 | 2019-03-11 | 2025-10-30 |
Showing 20 of 88. Sign in to see all of them.
Precursor Cell Lymphoblastic Leukemia-Lymphoma (11) · Shock, Septic (11) · Leukemia (10) · Sepsis (10) · Adrenal Insufficiency (7) · Lymphoma (7) · Prostatic Neoplasms (6) · Adrenal Hyperplasia, Congenital (5) · Burkitt Lymphoma (4) · Shock (4) · Anemia, Refractory, with Excess of Blasts (3) · COVID-19 (3) · Leukemia, Biphenotypic, Acute (3) · Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (3) · Addison Disease (2)
Children's Oncology Group (9) · National Cancer Institute (NCI) (5) · Neurocrine UK Limited (4) · Dana-Farber Cancer Institute (3) · University of Versailles (3) · Assistance Publique - Hôpitaux de Paris (2) · Eastern Cooperative Oncology Group (2) · European Organisation for Research and Treatment of Cancer - EORTC (2) · LEO Pharma (2) · Merck Sharp & Dohme LLC (2) · NICHD Neonatal Research Network (2) · Nanjing PLA General Hospital (2) · University Hospital, Tours (2) · Agnes (1) · Alliance for Clinical Trials in Oncology (1)
United States (33) · France (22) · Canada (17) · Australia (13) · Germany (11) · United Kingdom (11) · New Zealand (10) · Italy (9) · Netherlands (8) · Puerto Rico (8) · Belgium (7) · Brazil (7) · Switzerland (7) · Czechia (6) · Israel (6)
Abbot R Laptook, MD (2) · Abhik Das, PhD (2) · Carl T D'Angio, MD (2) · Christian Brun Buisson, MD (2) · Didier Keh, MD (2) · Djillali Annane, MD (2) · Edward F Bell, MD (2) · Krisa P Van Meurs, MD (2) · Michele C Walsh, MD (2) · Seetha Shankaran, MD (2) · Uday Devaskar, MD (2) · William Truog, MD (2) · A. O. Sartor, MD (1)
PMID 23525934, PMID 27695824, PMID 33527139, PMID 41732008, PMID 10499612, PMID 10722036, PMID 10820362, PMID 1138591, PMID 11426549, PMID 11502226, PMID 12239143, PMID 12454520, PMID 12545007, PMID 12560440, PMID 12700374, PMID 14747052, PMID 15020604, PMID 15353542, PMID 15368546, PMID 15637138, PMID 15767942, PMID 1607900, PMID 16570523, PMID 16609069, PMID 16888080, PMID 17039234, PMID 17132719, PMID 17138821, PMID 17404083, PMID 17407135, PMID 17611565, PMID 18089878, PMID 18184957, PMID 18353115, PMID 18371107, PMID 18493992, PMID 19005182, PMID 19020548, PMID 19029421, PMID 19304957, PMID 19884541, PMID 19895612, PMID 20007809, PMID 20056794, PMID 20103758, PMID 20124218, PMID 20332511, PMID 20378563, PMID 20407035, PMID 20413658
U10CA180886 (7), U10CA098543 (6), 2023 (3), U10HD021364 (2), U10HD021373 (2), U10HD021385 (2), U10HD027851 (2), U10HD027853 (2), U10HD027856 (2), U10HD027880 (2), U10HD027904 (2), U10HD034216 (2), U10HD036790 (2), U10HD040492 (2), U10HD040689 (2)