9 completed, 2 terminated, 2 withdrawn, 1 unknown. 14 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 14 | Completed 9, Terminated 2, Withdrawn 2, Unknown 1 |
| Phase 2 | 4 | Completed 2, Terminated 1, Withdrawn 1 |
Follow Glutamine: new trials by email Literature Review of Glutamine trials Research Report on Glutamine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Glutamine to Treat Intestinal Permeability in Functional Dyspepsia Glutamine, Placebo - Functional Dyspepsia | Phase 1 / Phase 2 | Completed | David J. Cangemi | 12 | 2023-02-16 | 2026-02-03 |
| Trial of First-line L-glutamine With Gemcitabine and Nab-paclitaxel in Advanced Pancreatic Cancer Gemcitabine, Nab-paclitaxel, L-glutamine - Advanced Pancreatic Adenocarcinoma, Pancreatic Cancer | Phase 1 | Completed | Jun Gong, MD | 18 | 2021-05-13 | 2025-08-06 |
| Glutamine PET Imaging in LAM Glutamine - Lymphangioleiomyomatosis (LAM) | Phase 1 | Completed | Vanderbilt University Medical Center | 5 | 2019-10-18 | 2021-08-11 |
| L-glutamine Treatment in Patients With Diverticulosis L-glutamine - Diverticulosis, Colonic | Phase 1 | Completed | Emmaus Medical, Inc. | 9 | 2019-07-19 | 2023-02-16 |
| The Effect of Pharmaceutical Grade L-glutamine (Endari) on Glycemic Control in Patients With Diabetes Mellitus Type II L-glutamine, No L-glutamine - Diabetes Mellitus, Type 2 | Phase 1 | Unknown | Hawaii Pacific Health | 25 | 2019-05-01 | 2019-05-13 |
| Lenalidomide Combined With Vorinostat/Gemcitabine/Busulfan/Melphalan With Autologous Stem-Cell Transplantation in Diffuse Large B-Cell Lymphoma of the ABC Subtype Lenalidomide, Vorinostat, Gemcitabine - Lymphoma | Phase 1 / Phase 2 | Terminated | M.D. Anderson Cancer Center | 8 | 2016-06-22 | 2019-12-13 |
| Belinostat Combined With Azacitidine/Gemcitabine/Busulfan/Melphalan With Autologous Stem-Cell Transplantation in Refractory or Relapsed Lymphoma Busulfan, Caphosol, Glutamine - Lymphoma | Phase 1 / Phase 2 | Withdrawn | M.D. Anderson Cancer Center | 2016-06-01 | 2016-05-04 | |
| L-glutamine Supplementation to Alleviate Symptoms of Taxane-Induced Neuropathy in Patients With Breast Cancer L-glutamine - Peripheral Neuropathy | Phase 1 | Withdrawn | Eastern Regional Medical Center | 2014-08-01 | 2017-07-12 | |
| Aza-SAHA-GBM With AutoSCT for Refractory Lymphoma Azacitidine, Vorinostat, Gemcitabine - Advanced Cancers, Lymphoma | Phase 1 / Phase 2 | Completed | M.D. Anderson Cancer Center | 61 | 2013-11-07 | 2020-01-27 |
| Novel Type 2 Diabetes Mellitus Preventive Therapies Glutamine (Pharmacological doses), Lifestyle change - Diabetes | Phase 1 | Completed | Boston Medical Center | 12 | 2010-05-01 | 2015-01-30 |
| Anaplerotic Therapy in Propionic Acidemia ornithine alpha ketoglutarate, glutamine, disodium citrate - Propionic Acidemia | Phase 1 | Completed | Nicola Longo | 3 | 2008-07-01 | 2015-01-21 |
| Effect of Glutamine on Intestinal Permeability in Crohn's Disease Glutamine, Whey protein - Crohn's Disease | Phase 1 | Completed | All India Institute of Medical Sciences | 30 | 2005-11-01 | 2009-02-06 |
| Enteral Glutamine Supplementation for the Patient With Major Torso Trauma Glutamine - Trauma, Critical Illness | Phase 1 | Terminated | The University of Texas Health Science Center, Houston | 20 | 2005-06-01 | 2010-04-23 |
| Glutamine and Intestinal Protein Metabolism Glutamine, Glucose, glutamine-antioxidants containing solution - Healthy Volunteers | Phase 1 | Completed | University Hospital, Rouen | 30 | 2004-04-01 | 2013-06-18 |
Lymphoma (3) · Breast Neoplasms (1) · Critical Illness (1) · Crohn Disease (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 2 (1) · Diverticulosis, Colonic (1) · Hyperammonemia (1) · Lymphangioleiomyomatosis (1) · Lymphoma, Large B-Cell, Diffuse (1) · Lymphoma, Non-Hodgkin (1) · Muscle Hypotonia (1) · Pancreatic Neoplasms (1) · Peripheral Nervous System Diseases (1) · Propionic Acidemia (1)
M.D. Anderson Cancer Center (3) · All India Institute of Medical Sciences (1) · Boston Medical Center (1) · David J. Cangemi (1) · Eastern Regional Medical Center (1) · Emmaus Medical, Inc. (1) · Hawaii Pacific Health (1) · Jun Gong, MD (1) · Nicola Longo (1) · The University of Texas Health Science Center, Houston (1) · University Hospital, Rouen (1) · Vanderbilt University Medical Center (1)
United States (10) · France (1) · India (1)
Yago Nieto, MD, PHD (3) · Carine M Lenders, MD, ScD, MS (1) · Charles Zerez, MD, PhD (1) · David Cangemi, MD (1) · Jack Medendorp (1) · Jun Gong, MD (1) · Margaret M McQuiggan, MS, RD, CNSD (1) · Nicola Longo, MD, PhD (1) · Timothy S Blackwell, MD (1) · Yogendra K Joshi, M.D., PhD. (1) · Yutaka L Niihara, MD (1)
PMID 21795435, PMID 28712602, PMID 42675216
M01RR002558 (1), R21DK077415 (1)