7 recruiting, 6 completed, 4 active not recruiting, 2 enrolling by invitation. 23 Phase 2, 5 Phase 1, 3 Not applicable, 2 Phase 3, 1 Early Phase 1.
Follow fisetin: new trials by email Literature Review of fisetin trials Research Report on fisetin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Fisetin for Improving Vascular Function in Older Adults: A Phase II Clinical Trial Fisetin, Placebo - Aging, Endothelial Dysfunction | Phase 2 | Not yet recruiting | University of Colorado, Boulder | 136 | 2026-11-01 | 2026-10-15 |
| Ongoing Lung Decline With Age Intensified Response Fisetin, Placebo - Age-Related Lung Function Decline | Phase 2 | Recruiting | Cedars-Sinai Medical Center | 40 | 2026-06-17 | 2026-10-15 |
| Pilot Trial of Fisetin in Healthy Volunteers and Older Patients With Multimorbidity Fisetin, Placebo - Multimorbidity, Healthy | Phase 1 / Phase 2 | Recruiting | Ove Andersen | 60 | 2026-03-24 | 2026-05-19 |
| Fisetin in Mild Alzheimer's Disease Fisetin - Alzheimer s Disease, Alzheimer Dementia | Phase 2 | Completed | Sunnybrook Health Sciences Centre | 5 | 2026-01-27 | 2026-08-20 |
| Fisetin Supplementation for Healthy Aging Fisetin, Placebo - Healthy | Not applicable | Recruiting | Ove Andersen | 120 | 2025-09-24 | 2026-05-19 |
| Medication Combinations of Dasatinib, Quercetin, Fisetin, Temozolomide, LMP744, and Autologous TLPO Vaccine for the Treatment of Previously Treated Glioma With Residual Disease Biospecimen Collection, Dasatinib, Fisetin - Glioma | Early Phase 1 | Recruiting | Mayo Clinic | 30 | 2025-08-12 | 2026-10-01 |
| Enhancing Recovery Through a Combined Mechanobiologic Intervention Following Meniscus Repair Fisetin, Placebo oral capsule - Meniscus Tear, Meniscus; Derangement | Phase 2 / Phase 3 | Withdrawn | Austin V Stone | 2025-07-01 | 2025-05-08 | |
| Fisetin to Reduce Senescence and Mobility Impairment in PAD Fisetin, Placebo - Peripheral Arterial Disease, Aging | Phase 2 | Recruiting | Northwestern University | 34 | 2024-09-30 | 2026-04-15 |
| Prevention of Frailty With Fisetin and Exercise in Breast Cancer Survivors Biospecimen Collection, Educational Intervention, Exercise Intervention - Anatomic Stage I Breast Cancer American Joint Committee on Cancer (AJCC) v8, Anatomic Stage II Breast Cancer AJCC v8 | Phase 2 | Recruiting | Jonsson Comprehensive Cancer Center | 164 | 2024-07-23 | 2026-07-30 |
| Fisetin to Improve Vascular Function in Older Adults Fisetin, Placebo - Aging, Endothelial Dysfunction | Phase 1 / Phase 2 | Active not recruiting | University of Colorado, Boulder | 70 | 2023-09-25 | 2026-09-25 |
| Senolytics Treatment of Interstitial Lung Disease in Common Variable Immunodeficiency Fisetin, Placebo - Common Variable Immunodeficiency, Interstitial Lung Disease Due to Systemic Disease | Phase 2 | Active not recruiting | Avni Joshi | 20 | 2023-04-12 | 2026-06-30 |
| GetHealthy-OA: A Program to Improve Pain and Function for Patients With Knee Osteoarthritis, Obesity, and Depression Fisetin, GetHealthy-OA mind-body program, Placebo oral capsule - Knee Osteoarthritis, Obese | Phase 2 / Phase 3 | Withdrawn | Cale Andrew Jacobs, PhD | 2023-04-01 | 2023-05-01 | |
| Fisetin to Improve Physical Function in Stage I-III Breast Cancer Survivors Biospecimen Collection, Fisetin, Placebo Administration - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | Phase 2 | Recruiting | Jonsson Comprehensive Cancer Center | 88 | 2023-03-27 | 2026-07-17 |
| A Study of Fisetin to Treat Carpal Tunnel Syndrome Fisetin - Carpal Tunnel Syndrome | Phase 2 | Completed | Peter C. Amadio, M.D. | 40 | 2022-10-09 | 2025-12-24 |
| Effect of Natural Senolytic Agents & NLRP3 Inhibitors on Osteoarthritis Quercetin and Fisetin tab., Quercetin Cap/Tab,Fisetin Cap/tab and Glycyrrhizin capsules, Placebo - Osteoarthritis | Not applicable | Suspended | Assiut University | 60 | 2022-07-01 | 2023-07-25 |
| An Open-Label Intervention Trial to Reduce Senescence and Improve Frailty in Adult Survivors of Childhood Cancer Dasatinib plus Quercetin, Fisetin - Frailty, Childhood Cancer | Phase 2 | Active not recruiting | St. Jude Children's Research Hospital | 120 | 2022-06-06 | 2026-09-30 |
| COVID-FIS: Pilot in COVID-19 (SARS-CoV-2) of Fisetin in Older Adults in Nursing Homes Fisetin, Placebo - Covid19, SARS-CoV Infection | Phase 2 | Terminated | Mayo Clinic | 20 | 2022-04-29 | 2025-08-26 |
| Senolytic Agent Improve the Benefit of Platelet-Rich Plasma and Losartan Fisetin, Placebo - Femoroacetabular Impingement | Phase 1 / Phase 2 | Unknown | Steadman Philippon Research Institute | 68 | 2021-10-24 | 2024-04-16 |
| COVFIS-HOME: COVID-19 Pilot Study of Fisetin to Alleviate Dysfunction and Decrease Complications Fisetin, Placebo - Covid19, Coronavirus Infection | Phase 2 | Completed | James L. Kirkland, MD, PhD | 55 | 2021-07-14 | 2023-08-01 |
| Use of Senolytic and Anti-Fibrotic Agents to Improve the Beneficial Effect of Bone Marrow Stem Cells for Osteoarthritis Fisetin, Losartan, Placebo - Losartan - Osteoarthritis, Knee | Phase 1 / Phase 2 | Unknown | Steadman Philippon Research Institute | 100 | 2021-05-18 | 2024-04-16 |
Showing 20 of 27. Sign in to see all of them.
Frailty (4) · Inflammation (4) · COVID-19 (3) · Osteoarthritis (3) · Osteoarthritis, Knee (3) · Alzheimer Disease (1) · Carpal Tunnel Syndrome (1) · Common Variable Immunodeficiency (1) · Coronavirus Infections (1) · Depression (1) · Diabetes Mellitus (1) · Diabetic Nephropathies (1) · Femoracetabular Impingement (1) · Glioma (1) · Intermittent Claudication (1)
Mayo Clinic (6) · Steadman Philippon Research Institute (3) · Jonsson Comprehensive Cancer Center (2) · Ove Andersen (2) · University of Colorado, Boulder (2) · Assiut University (1) · Austin V Stone (1) · Avni Joshi (1) · Cale Andrew Jacobs, PhD (1) · Cedars-Sinai Medical Center (1) · James L. Kirkland, MD, PhD (1) · Northwestern University (1) · Peter C. Amadio, M.D. (1) · St. Jude Children's Research Hospital (1) · Sundeep Khosla, M.D. (1)
United States (23) · Denmark (2) · Canada (1) · Egypt (1)
Sundeep Khosla, MD (3) · Juliette Tavenier (2) · Line Jee Hartmann Rasmussen (2) · Matthew J Rossman, PhD (2) · Morten B Houlind (2) · Adel A. Gomaa, Ph.D. (1) · Austin Stone, MD, PhD (1) · Avni Joshi, MD, MS (1) · Avni Y. Joshi, MD, MS (1) · Brandon P Verdoorn, MD (1) · Cale Jacobs, PhD (1) · Gregory T. Armstrong, MD, MSCE (1) · James L Kirkland, MD, PhD (1) · Jan O Nehlin (1) · Jarred W Younger, PhD (1)
PMID 33802272, PMID 33802381, PMID 33915962, PMID 38956196, PMID 39823170, PMID 40152935, PMID 41835341
P30CA016042 (2), 1UG3AR077748-01 (1), 2023 (1), K76AG074918 (1), R01AG072301 (1), R01AG094826 (1), R01CA280088 (1), R21CA277660 (1), U01CA246510 (1)