25 completed, 16 unknown, 15 recruiting, 6 active not recruiting. 24 Phase 2, 14 Not applicable, 14 Phase 3, 3 Phase 1, 1 Phase 4.
Follow Esophagectomy: new trials by email Literature Review of Esophagectomy trials Research Report on Esophagectomy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Camrelizumab, Chemotherapy and Ivarmacitinib in Patients With Resectable Esophageal Squamous Cell Carcinoma Camrelizumab, Esophagectomy, Sample - Esophageal Squamous Cell Carcinoma, Neoadjuvant Therapy | Phase 2 | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 45 | 2026-08-17 | 2026-10-02 |
| Neoadjuvant Ivonescimab（AK112） Combined With Chemotherapy in Patients With Resectable Esophageal Squamous Cell Carcinoma Ivonescimab（AK112), Albumin paclitaxel, carboplatin AUC=5, neoadjuvant therapy, Esophagectomy, Sample - Esophageal Squamous Cell Carcinoma, Neoadjuvant Therapy | Phase 2 | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 49 | 2026-06-03 | 2026-10-02 |
| Intensive Nutritional Support in Conversion Therapy for Locally Advanced Unresectable ESCC PD-1 Inhibitor plus Chemotherapy, Oral Enteral Nutritional Preparation, Esophagectomy with lymph node dissection - Esophageal Squamous Cell Carcinoma, Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma | Phase 2 | Recruiting | Sichuan University | 118 | 2026-04-01 | 2026-04-15 |
| Registry Study of People Who Are Having an Esophagectomy and Are at High Risk of Anastomotic Leak Esophagectomy - Esophageal Malignant Neoplasm Primary, Anastomotic Leak | Recruiting | Memorial Sloan Kettering Cancer Center | 40 | 2026-02-25 | 2026-03-04 | |
| Infiltration Pattern of Locally Advanced ESCC Esophagectomy - Esophageal Squamous Cell Carcinoma (ESCC), Infiltration | Enrolling by invitation | Shanghai Chest Hospital | 30 | 2025-10-01 | 2026-05-05 | |
| Neoadjuvant Immunotherapy Combined With Chemotherapy Sequenced With Endoscopic Resection for Esophageal Cancer (Endosurgery-02) Tislelizumab, Carboplatin, Nab-paclitaxel - Esophageal Squamous Cell Carcinoma (ESCC) | Phase 1 | Recruiting | Shanghai Zhongshan Hospital | 60 | 2025-07-15 | 2026-01-05 |
| Shanghai Clinical Cohort - Esophageal Cancer esophagectomy - Esophageal Cancer, Esophagectomy | Completed | Shanghai Chest Hospital | 2116 | 2025-07-01 | 2026-04-15 | |
| Adbelimumab Combined With Chemotherapy and Apatinib in Patients With Resectable Esophageal Squamous Cell Carcinoma Adbelimumab, Albumin paclitaxel, Carboplatin, Apatinib, Esophagectomy, Collecting samples from participant - Esophageal Squamous Cell Carcinoma, Neoadjuvant Treatment | Phase 2 | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 35 | 2024-08-08 | 2025-12-02 |
| Investigating Outcomes of Elective Robotic Transhiatal Esophagectomy Esophagectomy - Esophagectomy | Recruiting | Northwestern University | 120 | 2023-07-11 | 2026-05-26 | |
| Bone Microstructure by Using HR-pQCT After Esophagectomy esophagectomy - Osteoporosis, Sarcopenia | Not yet recruiting | Nagasaki University | 118 | 2023-05-25 | 2023-04-24 | |
| Serplulimab Combined With Chemotherapy in Patients With Resectable Esophageal Squamous Cell Carcinoma Serplulimab, Albumin paclitaxel, carboplatin AUC=5, neoadjuvant therapy, Esophagectomy, sample - Esophageal Squamous Cell Carcinoma, Neoadjuvant Therapy | Phase 2 | Active not recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 48 | 2022-12-01 | 2025-12-02 |
| Patient-reported Outcomes in Preoperative Immunochemotherapy/Radiotherapy-treated Esophageal Cancer Patients Paclitaxel-albumin, Cisplatin, Carboplatin - Esophageal Squamous Cell Carcinoma, Patient-reported Outcomes | Phase 2 | Unknown | Guangdong Provincial People's Hospital | 50 | 2022-11-30 | 2022-11-28 |
| PD-1 Inhibitor Combined With Neoadjuvant Chemoradiotherapy Plus Surgery for Locally Advanced ESCC (NEOCRTEC2101) Sintilimab, Preoperative radiotherapy, Paclitaxel - Squamous Cell Esophageal Carcinoma, Esophageal Cancer | Phase 3 | Recruiting | Sun Yat-sen University | 422 | 2022-11-01 | 2026-04-30 |
| Additional Consolidative Esophagectomy for the Patients With Oligometastatic Resectable ESCC Esophagectomy - Esophageal Squamous Cell Carcinoma, Oligometastatic Disease | Not applicable | Active not recruiting | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 141 | 2022-11-01 | 2023-07-18 |
| Study of Neoadjuvant Nivolumab or Placebo Plus Chemotherapy Followed by Surgery and Adjuvant Treatment in Subjects With Resectable ESCC Nivolumab, Cisplatin, Paclitaxel - Esophageal Squamous Cell Carcinoma | Phase 2 / Phase 3 | Unknown | Shanghai Zhongshan Hospital | 90 | 2022-06-01 | 2022-06-15 |
| Surgery or Chemoradiotherapy for Cervical Esophageal Cancer Esophagectomy - Cervical Esophageal Cancer | Not applicable | Recruiting | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 192 | 2022-04-10 | 2022-04-14 |
| ChemoRadiation And Tislelizumab for Esophageal/EGJ Cancer Intravenous Tislelizumab, Chemotherapy, Fractionated radiation - Esophageal Cancer, Esophagogastric Junction Cancer | Phase 2 | Withdrawn | Zhonglin Hao | 2022-04-01 | 2022-11-08 | |
| Unintentional Weight Loss After Oesophagectomy oesophagectomy - Oesophageal Cancer | Not applicable | Unknown | University College Dublin | 64 | 2021-06-30 | 2022-04-13 |
| Chemoradiotherapy Followed by Planned Surgery or by Surveillance and Surgery Only When Needed for Oesophageal Cancer Neoadjuvant radiotherapy (arm A), Carboplatin, paclitaxel, Esophagectomy - Esophageal Squamous Cell Carcinoma | Phase 3 | Recruiting | Karolinska University Hospital | 1020 | 2020-11-27 | 2025-03-06 |
| Carrelizumab, Chemotherapy and Apatinib in the Neoadjuvant Treatment of Resectable Esophageal Squamous Cell Carcinoma Carillizumab, Esophagectomy, Samples - Esophageal Squamous Cell Carcinoma, Neoadjuvant Therapy | Phase 2 | Active not recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 42 | 2020-11-23 | 2026-10-02 |
Showing 20 of 71. Sign in to see all of them.
Esophageal Neoplasms (44) · Esophageal Squamous Cell Carcinoma (18) · Carcinoma, Squamous Cell (6) · Adenocarcinoma (4) · Neoplasms (4) · Adenocarcinoma Of Esophagus (3) · Anastomotic Leak (2) · Esophageal Diseases (2) · Obesity (2) · Radiation Injuries (2) · Sarcopenia (2) · Barrett Esophagus (1) · Brain Neoplasms (1) · Deglutition Disorders (1) · Lymphatic Metastasis (1)
Second Affiliated Hospital, Zhejiang University, School of Medicine (5) · Shanghai Chest Hospital (4) · National Taiwan University Hospital (3) · Shanghai Zhongshan Hospital (3) · St. James's Hospital, Ireland (3) · Sun Yat-sen University (3) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences (2) · Chinese Academy of Medical Sciences (2) · Chinese University of Hong Kong (2) · Fudan University (2) · Memorial Sloan Kettering Cancer Center (2) · UMC Utrecht (2) · University Hospital, Lille (2) · University of Bologna (2) · All India Institute of Medical Sciences (1)
China (28) · United States (17) · Ireland (6) · France (4) · Taiwan (4) · Netherlands (3) · India (2) · Italy (2) · South Korea (2) · Sweden (2) · Australia (1) · Belgium (1) · Canada (1) · Germany (1) · Norway (1)
Christophe Mariette, MD, PhD (2) · Daniela Molena, MD (2) · Hong Yang, Ph.D., M.D. (2) · Jianan Wang (2) · Weilin Wang (2) · Agnieszka Fronczek, MD (1) · Angus CW Chan, MD (1) · Ankit Bharat, MD (1) · Anna Brzozowska, MD, PhD (1) · Bentong Yu, Master (1) · Bernard Meunier, MD, PhD (1) · Brian E Louie, MD (1) · Carel Le Roux, Pr, MD (1) · Caroline Gronnier, MD (1)
PMID 21684205, PMID 22646630, PMID 26808342, PMID 30308612, PMID 10235156, PMID 11870157, PMID 12049861, PMID 14967459, PMID 15555621, PMID 16235286, PMID 1742526, PMID 17462405, PMID 17917772, PMID 18498797, PMID 19258111, PMID 19465425, PMID 21233603, PMID 21462364, PMID 21557015, PMID 21769467, PMID 22555809, PMID 22565611, PMID 22668811, PMID 22867894, PMID 22887465, PMID 23165781, PMID 23199187, PMID 23274533, PMID 23458447, PMID 23783553, PMID 23865505, PMID 23992097, PMID 24078662, PMID 24609941, PMID 24743609, PMID 24888266, PMID 24982463, PMID 25274134, PMID 25379847, PMID 25650816, PMID 25691612, PMID 26135681, PMID 26254683, PMID 26313683, PMID 26338060, PMID 26515945, PMID 26742998, PMID 27412386, PMID 28187044, PMID 28317872
R33CA127055 (1), U10CA180822 (1), U10CA180868 (1)