5 unknown, 3 completed, 3 recruiting, 2 terminated. 14 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 14 | Unknown 5, Completed 3, Recruiting 3, Terminated 2, Active not recruiting 1 |
| Phase 2 | 3 | Unknown 3 |
Follow Esophagectomy: new trials by email Literature Review of Esophagectomy trials Research Report on Esophagectomy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| PD-1 Inhibitor Combined With Neoadjuvant Chemoradiotherapy Plus Surgery for Locally Advanced ESCC (NEOCRTEC2101) Sintilimab, Preoperative radiotherapy, Paclitaxel - Squamous Cell Esophageal Carcinoma, Esophageal Cancer | Phase 3 | Recruiting | Sun Yat-sen University | 422 | 2022-11-01 | 2026-04-30 |
| Study of Neoadjuvant Nivolumab or Placebo Plus Chemotherapy Followed by Surgery and Adjuvant Treatment in Subjects With Resectable ESCC Nivolumab, Cisplatin, Paclitaxel - Esophageal Squamous Cell Carcinoma | Phase 2 / Phase 3 | Unknown | Shanghai Zhongshan Hospital | 90 | 2022-06-01 | 2022-06-15 |
| Chemoradiotherapy Followed by Planned Surgery or by Surveillance and Surgery Only When Needed for Oesophageal Cancer Neoadjuvant radiotherapy (arm A), Carboplatin, paclitaxel, Esophagectomy - Esophageal Squamous Cell Carcinoma | Phase 3 | Recruiting | Karolinska University Hospital | 1020 | 2020-11-27 | 2025-03-06 |
| Comparison of Esophagectomy and Chemoradiation for Patients With cN0-pT1b Stage Esophageal Squamous Cell Carcinoma esophagectomy, chemoradiation, active surveillance - Esophageal Cancer | Phase 3 | Recruiting | Shanghai Chest Hospital | 176 | 2019-09-01 | 2019-10-22 |
| Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer Biospecimen Collection, Capecitabine, Carboplatin - Clinical Stage I Esophageal Adenocarcinoma AJCC v8, Clinical Stage I Esophageal Squamous Cell Carcinoma AJCC v8 | Phase 3 | Active not recruiting | NRG Oncology | 300 | 2019-06-26 | 2026-08-24 |
| Robot-assisted Esophagectomy Versus Conventional Thoracoscopic Esophagectomy esophagectomy - Esophageal Cancer, Esophageal Carcinoma | Phase 3 | Unknown | Shanghai Chest Hospital | 360 | 2017-07-29 | 2020-02-05 |
| Comparing Paclitaxel/Cisplatin and Cisplatin/5-fluorouracil in Neo-CRT for ESCC neoadjuvant chemoradiation - Esophageal Squamous Cell Carcinoma, Chemoradiation | Phase 2 / Phase 3 | Unknown | National Taiwan University Hospital | 248 | 2017-03-01 | 2022-06-07 |
| Study of Docetaxel or Vinorelbine Plus Cisplatin in Neoadjuvant Chemoradiotherapy for Esophageal Cancer (NEOCRTEC308) Docetaxel, Cisplatin, Radiation - Esophageal Squamous Cell Carcinoma, Esophageal Cancer | Phase 3 | Unknown | Sun Yat-sen University | 610 | 2015-07-01 | 2024-01-16 |
| Role of Esophagectomy in Complete Responders to CCRT esophagectomy - Esophageal Squamous Cell Carcinoma | Phase 3 | Terminated | Asan Medical Center | 486 | 2012-11-01 | 2017-08-29 |
| Robot-assisted Thoraco-laparoscopic Esophagectomy Versus Open Transthoracic Esophagectomy Esophagectomy - Esophageal Carcinoma, Esophageal Cancer | Phase 3 | Completed | UMC Utrecht | 112 | 2012-04-01 | 2020-03-26 |
| Efficacy and Safety Study of the Combined Modality Therapy in Adenocarcinoma of the Esophago-gastric Junction preoperative chemo- and chemoradiotherapy, Surgical resection - Adenocarcinoma of the Gastroesophageal Junction | Phase 2 / Phase 3 | Unknown | Medical University of Lublin | 100 | 2012-01-01 | 2013-02-05 |
| A Phase III Study of En Bloc Versus Non-En Bloc Esophagectomy in Esophageal Cancer Esophagectomy - Esophageal Neoplasms | Phase 3 | Terminated | Weill Medical College of Cornell University | 4 | 2008-09-01 | 2012-08-13 |
| Surgery or Chemoradiation for Esophageal Cancer Esophagectomy, Definitive chemoradiation - Esophageal Cancers | Phase 3 | Completed | Chinese University of Hong Kong | 40 | 2000-07-01 | 2009-12-16 |
| Multi-Center Prospective Randomized Trial Comparing Standard Esophagectomy Against Chemo-Radiotherapy for Treatment of Squamous Esophageal Cancer - Early Results From the Chinese University Research Group for Esophageal Cancer (CURE) Esophagectomy, Chemoradiation - Esophageal Cancer | Phase 3 | Completed | Chinese University of Hong Kong | 80 | 2000-07-01 | 2005-09-14 |
Esophageal Neoplasms (8) · Esophageal Squamous Cell Carcinoma (6) · Adenocarcinoma (1) · Carcinoma, Squamous Cell (1)
Chinese University of Hong Kong (2) · Shanghai Chest Hospital (2) · Sun Yat-sen University (2) · Asan Medical Center (1) · Karolinska University Hospital (1) · Medical University of Lublin (1) · NRG Oncology (1) · National Taiwan University Hospital (1) · Shanghai Zhongshan Hospital (1) · UMC Utrecht (1) · Weill Medical College of Cornell University (1)
China (6) · Taiwan (2) · United States (2) · Canada (1) · Ireland (1) · Netherlands (1) · Norway (1) · Poland (1) · South Korea (1) · Sweden (1)
Agnieszka Fronczek, MD (1) · Angus CW Chan, MD (1) · Anna Brzozowska, MD, PhD (1) · Bentong Yu, Master (1) · Ewa Kurys-Denis, MD, PhD (1) · Florian Lordick, MD, PhD (1) · Grzegorz Wallner, Professor (1) · Hecheng Li, Master (1) · Hezhong Chen, Master (1) · Hong Yang, Ph.D., M.D. (1) · Lijie Tan, Master (1)
PMID 16235286, PMID 19465425, PMID 21233603, PMID 21684205, PMID 22867894, PMID 22887465, PMID 23165781, PMID 23199187, PMID 23274533, PMID 23865505, PMID 24982463, PMID 30308612, PMID 31226960, PMID 32611448, PMID 34171870, PMID 35912196, PMID 36910109, PMID 40375301, PMID 41005671, PMID 41932350, PMID 8805926
U10CA180822 (1), U10CA180868 (1)