8 completed, 3 terminated, 2 recruiting, 2 unknown. 17 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 17 | Completed 8, Terminated 3, Recruiting 2, Unknown 2, Not yet recruiting 1, Withdrawn 1 |
Follow Dipyrone: new trials by email Literature Review of Dipyrone trials Research Report on Dipyrone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of the Effectiveness of Paracetamol With Ibuprofen or Paracetamol With Metamizole in Treating Pain in Acute Pancreatitis in Children The initial pain assessment, Drug administration according to protocol (paracetamol + ibuprofen OR paracetamol + metamizol), The effectiveness of the treatment - Pancreatitis, Acute, Pain, Acute | Phase 4 | Recruiting | Medical University of Warsaw | 78 | 2025-09-01 | 2025-08-24 |
| Antipyretic Treatment for Intrapartum Fever: Dipyrone vs Acetaminophen (RCT) Acetaminophen, dipyrone - Intrapartum Fever, Chorioamnionitis | Phase 4 | Not yet recruiting | Wolfson Medical Center | 140 | 2025-08-01 | 2025-07-03 |
| Comparing the Safety and Effectiveness of Different Doses of Morphine Administered in Spinal Anethesia for Pain Relief After Hip Replacement Surgery Spinal Anesthesia (bupivacaine), Postoperative pain management with acetaminophen, PCA IV Oxycodone - Analgesics, Opioid, Anesthesia, Spinal | Phase 4 | Recruiting | Medical University of Silesia | 120 | 2025-03-04 | 2026-02-12 |
| Ibuprofen vs Dipyrone After C-section in Preeclampsia medication 1, medication 2 - Preeclampsia | Phase 4 | Completed | Instituto Materno Infantil Prof. Fernando Figueira | 74 | 2022-10-15 | 2023-06-09 |
| Efficacy of Metamizole Versus Ibuprofen and a Short Educational Intervention Versus Standard Care in Acute Low Back Pain Metamizole Sodium, Ibuprofen 600 mg, Patient education - Low Back Pain | Phase 4 | Unknown | Insel Gruppe AG, University Hospital Bern | 120 | 2019-12-15 | 2024-02-07 |
| Impact of Intra- and Postoperative Continuous Infusion of Lidocaine on Analgesia in Vascular Anaesthesia lidocaine 10mg/ml, Placebo, Metamizole - Abdominal Aorta Aneurysm, Abdominal Aorta Atheroma | Phase 4 | Completed | Łukasz Krzych | 87 | 2019-01-29 | 2022-12-21 |
| Evaluation of the Roll of IV Fluids in the Treatment of Renal Colic 0.9% Sodium-chloride, Placebos, Optalgin, Voltaren, Morphine - Renal Colic | Phase 4 | Withdrawn | Sheba Medical Center | 2018-06-01 | 2021-10-04 | |
| TAP vs QLB in Patients After Cesarean Delivery TAP (transversus abdominis plane block), QL (quadratus lumborum block), Ropivacaine - Cesarean Section, Postoperative Pain | Phase 4 | Completed | Medical University of Lublin | 105 | 2018-02-07 | 2023-11-24 |
| Regional Analgesia After Cesarean Section TAP (transversus abdominis plane block), QLB (quadratus lumborum block), Stimuplex Ultra 360 needle - Cesarean Section, Pain, Postoperative | Phase 4 | Completed | Medical University of Lublin | 105 | 2017-09-04 | 2020-02-18 |
| Comparison of Two Pain-treatment Techniques After Cesarean Section TAP (transversus abdominis plane block), QL (quadratus lumborum block), Bupivacaine - Cesarean Section, Pain Management | Phase 4 | Completed | Michał Borys | 232 | 2017-06-01 | 2023-11-28 |
| Comparing Protocols for Analgesia Following Elective Cesarean Section Acetaminophen, Ibuprofen 400 mg, Dipyrone - Postoperative Pain, Post-Cesarean Section | Phase 4 | Unknown | Wolfson Medical Center | 120 | 2017-03-01 | 2018-08-09 |
| Delirium in Elderly Patients With Trauma of the Hip Bupivacaine, Acetaminophen, Diclofenac - Hip Fractures, Anesthesia | Phase 4 | Terminated | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 239 | 2016-05-01 | 2023-08-04 |
| Potential Benefit of the Combination of Metamizole and Ibuprofen After Third Lower Molar Extraction Metamizole and Ibuprofen, Metamizole and Placebo, Ibuprofen and Placebo - Pain, Postoperative | Phase 4 | Completed | University Hospital, Basel, Switzerland | 36 | 2016-02-15 | 2021-05-04 |
| Diclofenac Premedication, as the Effect of Preemptive Analgesia After Post-thoracotomy Chest and Shoulder Pain Diclofenac, Midazolam, Atropine - Pain, Inadequate or Impaired Respiratory Function | Phase 4 | Completed | University of Debrecen | 3 | 2014-04-01 | 2017-03-09 |
| Ibuprofen, Acetaminophen and Dipyrone to Fever Control in Children ibuprofen, dipyrone, acetaminophen - Fever | Phase 4 | Completed | Mantecorp Industria Quimica e Farmaceutica Ltd. | 396 | 2007-01-01 | 2011-05-24 |
| Metamizol for the Treatment of Neoplastic Chronic Pain Metamizole, Diclofenac, Diclofenac placebo - Pain | Phase 4 | Terminated | Boehringer Ingelheim | 6 | 2000-03-01 | 2014-07-18 |
| Efficacy and Safety of Metamizole Versus Placebo as Antithermic Therapy in the Acute Phase of Ischemic Stroke Metamizole, Placebo - Stroke | Phase 4 | Terminated | Boehringer Ingelheim | 58 | 1998-12-01 | 2014-07-10 |
Agnosia (5) · Pain, Postoperative (5) · Neuralgia (3) · Acute Pain (2) · Pain (2) · Acute Kidney Injury (1) · Aortic Aneurysm, Abdominal (1) · Chorioamnionitis (1) · Fever (1) · Hip Fractures (1) · Low Back Pain (1) · Pancreatic Diseases (1) · Pancreatitis (1) · Pre-Eclampsia (1) · Renal Colic (1)
Boehringer Ingelheim (2) · Medical University of Lublin (2) · Wolfson Medical Center (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Insel Gruppe AG, University Hospital Bern (1) · Instituto Materno Infantil Prof. Fernando Figueira (1) · Mantecorp Industria Quimica e Farmaceutica Ltd. (1) · Medical University of Silesia (1) · Medical University of Warsaw (1) · Michał Borys (1) · Sheba Medical Center (1) · University Hospital, Basel, Switzerland (1) · University of Debrecen (1) · Łukasz Krzych (1)
Poland (6) · Brazil (2) · Israel (2) · Switzerland (2) · Hungary (1) · Netherlands (1)
Ilia Kleiner, MD (1) · Maria M. Wertli, MD PhD (1) · Markus Hollmann, MD, PhD, PhD (1) · Michal Kovo, MD (1) · Miroslaw Czuczwar, MD, PhD (1) · Wilhelm Ruppen, PD Dr. med (1)
PMID 22678319, PMID 33238043, PMID 33345816, PMID 33800559, PMID 38714924
2015 (1), 2018 (1)