133 completed, 51 unknown, 22 recruiting, 18 terminated. 183 Not applicable, 18 Phase 4, 7 Phase 1, 7 Phase 2, 7 Phase 3.
Follow CPAP: new trials by email Literature Review of CPAP trials Research Report on CPAP
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Continued Pressure for Alveolar Protection (CPAP Trial) CPAP, Nasal Cannula - Bronchopulmonary Dysplasia (BPD) | Not applicable | Recruiting | NICHD Neonatal Research Network | 860 | 2026-11-05 | 2026-07-14 |
| Transcutaneous Electrical Stimulation in Patients With Obstructive Sleep Apnoea ZeusOSA, CPAP - Obstructive Sleep Apnea | Not applicable | Not yet recruiting | Zeus Sleep Ltd | 186 | 2026-09-30 | 2026-09-22 |
| A Comparative Effectiveness Study of Positive Airway Pressure (PAP) Therapy, Dental Device, and Atomoxetine-Oxybutynin for Treatment of Obstructive Sleep Apnea in Adults Positive airway pressure (PAP) therapy, Sleep dental device, Atomoxetine-oxybutynin - Obstructive Sleep Apnea (OSA) | Phase 4 | Recruiting | Sairam Parthasarathy | 2400 | 2026-09-04 | 2026-10-19 |
| Entropy-based Physiological Signal Analysis in Patients With Obstructive Sleep Apnoea Continuous Positive Airway Pressure Therapy - Obstructive Sleep Apnoea (OSA) | Completed | King's College London | 56 | 2026-06-11 | 2026-10-30 | |
| Effective of Early Treatment of Insomnia on the Adherence of CPAP digital CBT-I, CPAP - Obstructive Sleep Apnea (OSA), Insomnia Chronic | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire Vaudois | 120 | 2026-06-01 | 2026-04-29 |
| Supplemental Oxygen and Oxygen Desaturations in Colonoscopies Breath-synchronized oxygen, CPAP, Control - Oxygen Desaturation, Apnea (Central and Obstructive) | Not applicable | Not yet recruiting | University of Utah | 280 | 2026-05-18 | 2026-04-07 |
| Pressure Targeting During High Flow Therapy in Premature Infants Pressure Targeted High Flow, CPAP - Preterm Infants, Respiratory Distress Syndrome (Neonatal) | Phase 2 | Not yet recruiting | University of Texas at Austin | 78 | 2026-05-01 | 2026-02-18 |
| A Randomised Feasibility Study of CPAP in Large Airway Collapse CPAP - Large Airway Collapse, Asthma | Not applicable | Recruiting | Liverpool School of Tropical Medicine | 60 | 2026-04-20 | 2026-09-14 |
| Sleep Apnea Biomarkers and Adherence to Continuous Positive Airway Pressure Continuous Positive Airway Pressure - Obstructive Sleep Apnea (OSA), CPAP | Recruiting | Clinique du Millenaire | 200 | 2026-02-18 | 2026-08-28 | |
| Positive Airway Pressure (PAP) System Evaluation in Volunteers CPAP - Obstruction Airway | Not applicable | Completed | University of Utah | 13 | 2026-02-10 | 2026-11-05 |
| Glaucoma Respsosne to Lifestyle Corrections in Sleep Apnea lifetyle corrections and CPAP, CPAP - Primary Open Angle Glaucoma, Obstructive Sleep Apnea | Not applicable | Recruiting | Cairo University | 40 | 2026-02-04 | 2026-03-03 |
| CPAP vs MAD for OSA in Patients With Cognitive Impairment. A Randomized Clinical Trial MAD, CPAP - Obstructive Sleep Apnea (OSA), Mild Cognitive Impairment | Not applicable | Recruiting | National University Hospital, Singapore | 260 | 2026-01-01 | 2026-01-21 |
| CPAP for Motion Management in Breast Radiotherapy; and Lung & Liver SABR CPAP - Cancer | Not applicable | Unknown | Waikato Hospital | 70 | 2025-10-01 | 2025-04-24 |
| Effect of CPAP Versus APAP in Patients With Obesity Undergoing Bariatric Surgery Protocol In the intervention group, patients will be treated with auto-adjusting APAP, providing variable pressures throughout the sleep hours., CPAP - Sleep Apnea, Obstructive, Bariatric Surgery | Not applicable | Not yet recruiting | Hospital Universitario Ramon y Cajal | 104 | 2025-09-15 | 2025-07-23 |
| Intermittent-Hypoxia Inhibits Neutrophil Extracellular Traps Formation: Role of Cathelicidins CPAP - Obstructive Sleep Apnea (OSA) | Not yet recruiting | Kun-Ta Chou | 120 | 2025-09-01 | 2025-09-11 | |
| Sleep Apnea Triggers of Atrial Fibrillation: N-of-1 Randomized Control Trial (SPARTA): CPAP - Afib, Sleep Apnea Syndrome, Obstructive | Not applicable | Recruiting | The Cleveland Clinic | 20 | 2025-08-25 | 2026-04-13 |
| Comparing CPAP and BiPAP for Sleep-Disordered Breathing in People with Cervical Spinal Cord Injuries CPAP, BiPAP - Spinal Cord Injuries (SCI), Sleep Disordered Breathing (SDB) | Not applicable | Not yet recruiting | University of British Columbia | 32 | 2025-08-01 | 2025-02-10 |
| Continous Positive Airway Pressure (CPAP) Support for Acute Hypoxemic Respiratory Failure in Burkina Faso CPAP - Acute Respiratory Failure | Not applicable | Recruiting | Université NAZI BONI | 240 | 2025-07-09 | 2025-07-28 |
| CPAP and Glucose Metabolism in Non-Diabetic OSA Subjects CPAP - Obstructive Sleep Apnea, Pre-diabetes | Not applicable | Not yet recruiting | Woolcock Institute of Medical Research | 100 | 2025-07-01 | 2025-04-01 |
| Changing Lifestyle in OSA Males Who Suffer Metabolic Syndrome and Impotence: Is There a Response? lifestyle changing plus CPAP, CPAP - Obstructive Sleep Apnea, Erectile Dysfunction | Not applicable | Recruiting | Cairo University | 40 | 2025-04-15 | 2025-05-07 |
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Sleep Apnea, Obstructive (131) · Sleep Apnea Syndromes (48) · Hypertension (14) · Obesity (11) · Respiratory Insufficiency (10) · Premature Birth (9) · Heart Failure (8) · Respiratory Distress Syndrome (8) · Hypoxia (7) · Microcephaly, Primary Autosomal Recessive, 6 (7) · Bronchopulmonary Dysplasia (6) · Pulmonary Atelectasis (6) · Sleep Wake Disorders (6) · Stroke (6) · Apnea (5)
National Taiwan University Hospital (9) · University of Sao Paulo (8) · Chang Gung Memorial Hospital (5) · Sociedad Española de Neumología y Cirugía Torácica (5) · University of California, San Diego (5) · University Hospital, Grenoble (4) · VA Office of Research and Development (4) · Assistance Publique - Hôpitaux de Paris (3) · Chinese University of Hong Kong (3) · Columbia University (3) · Mahidol University (3) · Philips Respironics (3) · University of Michigan (3) · University of Pennsylvania (3) · University of Utah (3)
United States (73) · Spain (20) · Brazil (18) · Taiwan (17) · France (15) · China (12) · Canada (9) · Italy (6) · United Kingdom (5) · Belgium (4) · Egypt (4) · Norway (4) · Switzerland (4) · Thailand (4) · Denmark (3)
Peilin Lee, M.D. (3) · Abinash Joshi, MD (2) · Ali MA Ismail, lecturer (2) · Daniel J Gottlieb, MD MPH (2) · Dennis Hwang, MD (2) · Francesca Facco, MD (2) · Kai Kuck, PhD (2) · Pei-Lin Lee, M.D., PhD (2) · Ricardo Osorio, MD (2) · Abbot R Laptook, MD (1) · Abbot R. Laptook, MD (1) · Abhik Das, PhD (1) · Alberto Alonso, Dr (1)
PMID 28548301, PMID 10685270, PMID 10706500, PMID 11335736, PMID 11433048, PMID 11468903, PMID 12603352, PMID 12650303, PMID 12706763, PMID 12740261, PMID 15141265, PMID 15475599, PMID 15537123, PMID 16162707, PMID 16579514, PMID 17050561, PMID 17404558, PMID 17452229, PMID 17452537, PMID 17804519, PMID 17936040, PMID 17975198, PMID 18347202, PMID 18413499, PMID 18452788, PMID 18539753, PMID 18584016, PMID 18646124, PMID 19101028, PMID 19249441, PMID 19357147, PMID 19523049, PMID 19567491, PMID 19948523, PMID 20464170, PMID 20472937, PMID 20472939, PMID 20488288, PMID 20564750, PMID 20587676, PMID 20825901, PMID 21262883, PMID 21276671, PMID 21471093, PMID 21493723, PMID 21632834, PMID 21804670, PMID 22301528, PMID 22323303, PMID 22334807
2019 (1), K12HD043441 (1), K23HL103850 (1), K23HL151880 (1), M01RR000633 (1), M01RR000750 (1), M01RR008084 (1), P01HL094307 (1), P30CA042014 (1), P50HD057796 (1), R01AG054435 (1), R01HL075078 (1), R01HL106041 (1), R01HL120354 (1), R01HL146127 (1)