292 completed, 78 unknown, 54 terminated, 18 withdrawn. 239 Phase 2, 112 Phase 3, 77 Phase 1, 51 Not applicable, 3 Phase 4.
Follow Conventional surgery: new trials by email Literature Review of Conventional surgery trials Research Report on Conventional surgery
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cost-utility Analysis of the Use of a Laser Fiber in the Management of Non-abscessed Pilonidal Cyst Laser fiber treatment, Conventional surgery - Non-abscessed Pilonidal Cyst | Not applicable | Not yet recruiting | Elsan | 150 | 2026-06-15 | 2026-06-16 |
| Piezoeletric Surgery vs Conventional Surgery for Treatment of MRONJ Piezoelectric surgery, Conventional surgery - Bisphosphonate-Associated Osteonecrosis of the Jaw, Osteonecrosis of the Jaw | Not applicable | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 34 | 2025-12-01 | 2025-09-22 |
| No Endotamponade for Macular Hole Repair: the NEMAR Study Conventional surgery, ILM flap with no gas tamponade - Macular Hole, Macular Hole Surgery | Not applicable | Recruiting | Chinese University of Hong Kong | 180 | 2025-09-16 | 2025-09-30 |
| Study on the Application of Intraoperative Optical Coherence Tomography Technique in the Diagnosis and Treatment of Lens Diseases Surgery with Intraoperative Optical Coherence Tomography application, Conventional surgery - Lens Diseases | Not applicable | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 600 | 2024-11-27 | 2025-05-22 |
| Chronic Subdural Hematoma Treatment With Embolization Versus Surgery Study Conventional Surgery, Middle Meningeal Artery Embolization (MMAE) - Chronic Subdural Hematoma | Not applicable | Recruiting | The University of Texas Medical Branch, Galveston | 520 | 2024-11-01 | 2026-05-22 |
| Sinus Tarsi Implant as an Adjuvant Procedure to Medial Displacement Calcaneal Osteotomy in the Treatment of Mobile Adult Acquired Flatfoot Deformity ProStop, sinus tarsi implant (STI), Conventional surgery - Acquired Adult Flatfoot Deformity, Flat Foot | Phase 4 | Recruiting | Region Skane | 130 | 2024-07-31 | 2025-12-02 |
| The Prognosis of Colorectal Cancer Patients After Indocyanine Green Fluorescence-guided Radical Surgery ICG Guided surgery, conventional surgery - Colorectal Cancer | Completed | Shanghai Tong Ren Hospital | 235 | 2024-07-15 | 2024-12-16 | |
| Diode Laser 940 Nm Versus Electrosurgical Device During Second Stage Implant Surgery on Bone and Soft Tissue Healing Conventional surgery, Diode laser 940 nm, Electrosurgical - Dental Implant, Bone Healing | Not applicable | Completed | Hams Hamed Abdelrahman | 33 | 2023-11-30 | 2024-09-24 |
| Transvaginal Diverticulum Wall Filling and Coverage Technique for Treating Female Circumferential Urethral Diverticulum Transvaginal Diverticulum Wall Filling and Coverage Technique, Conventional surgery - Circumferential Female Urethral Diverticulum | Not applicable | Enrolling by invitation | West China Hospital | 100 | 2023-06-01 | 2026-10-16 |
| Effect of Piezoelectric Device on Intraoperative Hemorrhage Control and Quality of Life conventional surgery, piezoelectric device - Periapical Lesion | Not applicable | Unknown | Postgraduate Institute of Dental Sciences Rohtak | 30 | 2022-11-01 | 2024-02-02 |
| Testing the Addition of the Immune Therapy Drugs, Tocilizumab and Atezolizumab, to Radiation Therapy for Recurrent Glioblastoma Atezolizumab, Biospecimen Collection, Conventional Surgery - Diffuse Astrocytoma, IDH-Wildtype, Recurrent Glioblastoma | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 61 | 2022-03-11 | 2026-09-23 |
| Testing Treatment With Encorafenib and Binimetinib Before Surgery for Melanoma With Lymph Node Involvement Binimetinib, Conventional Surgery, Encorafenib - Melanoma of Unknown Primary, Metastatic Malignant Neoplasm in Lymph Node | Phase 2 | Terminated | ECOG-ACRIN Cancer Research Group | 3 | 2021-09-22 | 2026-10-06 |
| Pembrolizumab, Dabrafenib, and Trametinib Before Surgery for the Treatment of BRAF-Mutated Anaplastic Thyroid Cancer Conventional Surgery, Dabrafenib, Intensity-Modulated Radiation Therapy - Thyroid Gland Anaplastic Carcinoma, Thyroid Gland Squamous Cell Carcinoma | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 30 | 2021-06-24 | 2026-10-08 |
| Botulinum Toxin Augmented Surgery vs Conventional Surgery in the Management of Large Angle Horizontal Deviations botulinum toxin augmented surgery, conventional surgery - Large Angle Horizontal Strabismus | Not applicable | Unknown | Assiut University | 46 | 2021-02-20 | 2021-02-21 |
| Clinical Trial to Test the Phenolization in Sacrococcygeal Pilonidal Disease phenolization, Conventional surgery - Sacrococcygeal Fistula, Pilonidal Sinus | Phase 4 | Completed | HJ23 | 122 | 2021-01-01 | 2022-06-07 |
| Supramarginal Resection in Glioblastoma Supramarginal resection, Conventional surgery - Glioblastoma | Not applicable | Active not recruiting | St. Olavs Hospital | 90 | 2020-07-01 | 2026-03-03 |
| Comparison of Diode Laser-Assisted Vestibuloplasty And Conventional Vestibuloplasty Diode Laser, Conventional Surgery, Low level laser therapy (LLLT) - Wound Heal, Vestibular Abnormality | Not applicable | Completed | Abant Izzet Baysal University | 52 | 2019-10-01 | 2022-02-23 |
| A Multicenter Trial of Radiofrequency Ablation vs. Surgery as Treatment of Papillary Thyroid Microcarcinoma. Radiofrequency Ablation, Conventional Surgery - Papillary Thyroid Microcarcinoma | Not applicable | Unknown | Second Affiliated Hospital, Zhejiang University, School of Medicine | 200 | 2019-06-01 | 2020-12-19 |
| Phase I/II Study of Perioperative Chemotherapy Plus Immunotherapy Followed by Surgery in Localized Esophageal and Gastroesophageal Adenocarcinoma Atezolizumab, Conventional Surgery, Fluorouracil - Clinical Stage II Esophageal Adenocarcinoma AJCC v8, Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8 | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 43 | 2019-02-19 | 2026-07-28 |
| Gemcitabine and Cisplatin Without Cystectomy for Patients With Muscle Invasive Bladder Urothelial Cancer and Select Genetic Alterations Gemcitabine Hydrochloride, Cisplatin, Pegfilgrastim - Infiltrating Bladder Urothelial Carcinoma, Stage II Bladder Urothelial Carcinoma | Phase 2 | Active not recruiting | Alliance for Clinical Trials in Oncology | 237 | 2018-12-10 | 2026-10-16 |
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Breast Neoplasms (62) · Colorectal Neoplasms (46) · Central Nervous System Neoplasms (44) · Rectal Neoplasms (44) · Sarcoma (40) · Glioblastoma (35) · Gliosarcoma (33) · Esophageal Neoplasms (32) · Brain Neoplasms (31) · Lung Neoplasms (31) · Astrocytoma (30) · Carcinoma, Non-Small-Cell Lung (30) · Colonic Neoplasms (27) · Head and Neck Neoplasms (27) · Neoplasm Metastasis (27)
National Cancer Institute (NCI) (29) · European Organisation for Research and Treatment of Cancer - EORTC (28) · Children's Oncology Group (26) · Memorial Sloan Kettering Cancer Center (18) · M.D. Anderson Cancer Center (14) · Radiation Therapy Oncology Group (14) · Alliance for Clinical Trials in Oncology (13) · Children's Cancer and Leukaemia Group (13) · Jonsson Comprehensive Cancer Center (11) · Roswell Park Cancer Institute (10) · Case Comprehensive Cancer Center (9) · SWOG Cancer Research Network (9) · UNICANCER (9) · City of Hope Medical Center (7) · Fox Chase Cancer Center (7)
United States (281) · United Kingdom (59) · Canada (50) · France (45) · Switzerland (37) · Netherlands (34) · Belgium (32) · Italy (32) · Australia (30) · Puerto Rico (24) · Germany (23) · Spain (19) · Sweden (19) · Austria (17) · Portugal (16)
Frank Berthold, MD (4) · Andrew David J. Pearson, MD, FRCP, DCh (3) · Ann Barrett (3) · Ian J. Lewis, MD (3) · Janice A. Kohler, MD, FRCP (3) · Lawrence P. Leichman, MD (3) · Nancy E. Kemeny, MD (3) · W.D. George, MD, MS, FRCS (3) · A. Bapsi Chakravarthy, MD (2) · Alan W. Craft, MD (2) · Alessandro Olivi, MD (2) · Aminah Jatoi, MD (2) · Bernard Nordlinger, MD (2) · Burton L. Eisenberg, MD (2) · Colin P. Dinney, MD (2)
PMID 23683550, PMID 25057165, PMID 27465021, PMID 37933882, PMID 10463285, PMID 10663329, PMID 10813118, PMID 10924966, PMID 11241082, PMID 11391598, PMID 11464889, PMID 11560968, PMID 11790211, PMID 11857322, PMID 11904735, PMID 11913730, PMID 12101494, PMID 12204666, PMID 12499279, PMID 12525193, PMID 12622453, PMID 12721262, PMID 12727829, PMID 12782596, PMID 12932669, PMID 13900261, PMID 14508361, PMID 14508838, PMID 14520092, PMID 14529772, PMID 14645636, PMID 14656276, PMID 14673042, PMID 14731343, PMID 15141043, PMID 15175957, PMID 15533252, PMID 15542800, PMID 15565574, PMID 15621990, PMID 15646530, PMID 15654272, PMID 15868587, PMID 15894098, PMID 15928663, PMID 15997446, PMID 15999362, PMID 16009958, PMID 16055865, PMID 16110020
P30CA043703 (11), U10CA032102 (9), P30CA033572 (8), U10CA098543 (7), P30CA006927 (6), P30CA016672 (6), P30CA006973 (5), P30CA015083 (4), P30CA008748 (3), U10CA031946 (3), U10CA180821 (3), U10CA180886 (3), 2004 (2), P30CA016087 (2), P30CA021765 (2)