8 completed. 8 Phase 3.
By phase and status
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All 8 trials
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|
Caspofungin Acetate, Fluconazole, or Voriconazole in Preventing Fungal Infections in Patients Following Donor Stem Cell Transplant
Caspofungin Acetate, Fluconazole, Laboratory Biomarker Analysis - Fungal Infection, Hematopoietic and Lymphoid Cell Neoplasm | Phase 3 | Completed | 292 | 2013-03-21 | 2024-10-16 |
Empirical Versus Preemptive Antifungal Therapy
caspofungin acetate - Fungal Infection, Leukemia | Phase 3 | Completed | 556 | 2012-03-01 | 2023-12-11 |
Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid Leukemia
Caspofungin Acetate, Fluconazole, Laboratory Biomarker Analysis - Acute Myeloid Leukemia, Adult Acute Monoblastic Leukemia | Phase 3 | Completed | 517 | 2011-04-04 | 2021-03-30 |
A Clinical Study of MK0991 (Caspofungin) in Japanese Patients With Deep-seated Candida or Aspergillus Infections (0991-062)(COMPLETED)
caspofungin acetate, Comparator: Micafungin sodium - Fungal Infection | Phase 3 | Completed | 121 | 2008-08-01 | 2017-03-23 |
A Study of Caspofungin Acetate (MK0991) for the Treatment of Esophageal Candidiasis or Invasive Candidiasis in Chinese Adults (MK-0991-066)
caspofungin acetate - Fungal Infection | Phase 3 | Completed | 63 | 2008-01-01 | 2017-03-24 |
A Multicenter, Randomized, Double-Blind, Comparative Study to Evaluate the Safety, Tolerability, and Efficacy of 2 Dosing Regimens of an Antifungal Drug in the Treatment of Fungal Infections in Adults (0991-801)(COMPLETED)
caspofungin acetate - Invasive Candidiasis | Phase 3 | Completed | 204 | 2006-01-01 | 2017-03-24 |
A 28 - 90 Days Study to Evaluate the Safety, Tolerability, and Efficacy of Caspofungin Injection as Empirical Therapy in Indian Adults With Persistent Fever and Neutropenia (0991-053)(COMPLETED)
caspofungin acetate - Fungal Infection | Phase 3 | Completed | 50 | 2005-06-01 | 2017-02-23 |
Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment
caspofungin acetate, liposomal amphotericin B - Cancer | Phase 3 | Completed | | 2000-08-01 | 2013-01-18 |
Conditions studied
Mycoses (6) · Leukemia, Myeloid, Acute (3) · Leukemia (2) · Neutropenia (2) · Blast Crisis (1) · Breast Neoplasms (1) · Burkitt Lymphoma (1) · Candidiasis, Invasive (1) · Carcinoma, Embryonal (1) · Carcinoma, Ovarian Epithelial (1) · Congenital Abnormalities (1) · Endodermal Sinus Tumor (1) · Fever (1) · Hematologic Neoplasms (1) · Hodgkin Disease (1)
Sponsors
Merck Sharp & Dohme LLC (4) · Children's Oncology Group (2) · European Organisation for Research and Treatment of Cancer - EORTC (1) · Memorial Sloan Kettering Cancer Center (1)
Countries
United States (3) · Canada (2) · Belgium (1) · Czechia (1) · France (1) · Germany (1) · Netherlands (1) · Puerto Rico (1) · Slovakia (1)
Top investigators
Christopher C Dvorak (1) · Kent Sepkowitz, MD (1) · Theoklis E Zaoutis (1)
Results publications
PMID 15459300, PMID 23052987, PMID 31688884, PMID 33136159, PMID 35906831
NIH funding
U10CA095861 (2), UG1CA189955 (2)