9 completed, 1 recruiting, 1 terminated. 5 Phase 3, 4 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Completed 3, Recruiting 1, Terminated 1 |
| Phase 1 | 4 | Completed 4 |
| Phase 2 | 3 | Completed 3 |
Follow Carisbamate: new trials by email Literature Review of Carisbamate trials Research Report on Carisbamate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults Carisbamate - Seizures, Lennox Gastaut Syndrome | Phase 3 | Recruiting | SK Life Science, Inc. | 252 | 2022-04-28 | 2025-07-24 |
| Bioavailability and Food Effect Study of 3 Types of Carisbamate Carisbamate - Healthy Subjects | Phase 1 | Completed | SK Life Science, Inc. | 33 | 2020-08-27 | 2021-10-07 |
| Carisbamate Safety Study in Adult and Pediatric Subjects With Lennox-Gastaut Syndrome Carisbamate - Lennox Gastaut Syndrome | Phase 1 | Completed | SK Life Science, Inc. | 15 | 2019-05-03 | 2024-04-04 |
| Carisbamate in Adult & Pediatric Subjects With Lennox-Gastaut Syndrome Carisbamate - Lennox Gastaut Syndrome | Phase 1 | Completed | SK Life Science, Inc. | 18 | 2019-02-07 | 2023-05-30 |
| Carisbamate as a Potential Treatment for Alcohol Dependence Carisbamate, Placebo - Alcohol Dependence, Alcohol Abuse | Phase 1 / Phase 2 | Completed | Baylor College of Medicine | 11 | 2013-02-01 | 2021-03-02 |
| An Open-Label Extension Study of the Safety and Tolerability of Carisbamate as Add-On Therapy in Patients With Partial Onset Seizures placebo, carisbamate - Epilepsy, Partial, Motor, Epilepsy, Complex Partial | Phase 3 | Completed | SK Life Science, Inc. | 403 | 2009-01-01 | 2013-06-18 |
| A Study of the Effectiveness, Safety, and Tolerability of Carisbamate as Add-On Therapy in Patients With Partial Onset Seizures. Carisbamate, placebo - Epilepsy, Partial, Motor, Epilepsy, Complex Partial | Phase 3 | Completed | SK Life Science, Inc. | 547 | 2009-01-01 | 2013-01-24 |
| Carisbamate Retention Study (CaReS): Comparative Study on the Long Term Effectiveness, Safety and Tolerability of Carisbamate Compared to Two Other Frequently Prescribed Anti-epileptic Drugs (AEDs) in Patients With Epilepsy. carisbamate, topiramate, levetiracetam - Epilepsy, Seizures | Phase 3 | Terminated | SK Life Science, Inc. | 89 | 2007-11-01 | 2013-01-29 |
| A Proof of Concept Study of the Effectiveness of Carisbamate in the Treatment of Essential Tremor Carisbamate, Placebo - Essential Tremor, Movement Disorders | Phase 2 | Completed | SK Life Science, Inc. | 62 | 2007-08-01 | 2013-01-24 |
| An Effectiveness and Safety Study With RWJ-333369 (Carisbamate) for the Study of Postherpetic Neuralgia (PHN). placebo, carisbamate - Postherpetic Neuralgia, Neuralgia | Phase 2 | Completed | SK Life Science, Inc. | 91 | 2007-03-01 | 2018-05-01 |
| An Open-Label Extension Study to Evaluate the Safety and Tolerability of RWJ 333369 as Adjunctive Therapy in Patients 16 Years and Older With Partial Onset Seizures. carisbamate - Epilepsy, Complex Partial Seizures | Phase 3 | Completed | SK Life Science, Inc. | 991 | 2007-02-01 | 2013-06-18 |
Seizures (5) · Lennox Gastaut Syndrome (4) · Epilepsies, Partial (3) · Epilepsy, Complex Partial (3) · Epilepsy (2) · Epilepsy, Partial, Motor (2) · Alcoholism (1) · Blister (1) · Chickenpox (1) · Essential Tremor (1) · Exanthema (1) · Herpes Zoster (1) · Movement Disorders (1) · Neuralgia (1) · Neuralgia, Postherpetic (1)
SK Life Science, Inc. (10) · Baylor College of Medicine (1)
United States (5) · Argentina (1) · Australia (1) · Colombia (1) · Germany (1) · Greece (1) · Hungary (1) · Israel (1) · Italy (1) · Mexico (1) · Poland (1) · Portugal (1) · Serbia (1) · South Korea (1) · Spain (1)
Marc Kamin, MD (3) · Ry R Forseth, Ph.D. (1) · Thomas F Newton, M.D (1)