22 unknown. 22 Phase 2, 3 Phase 1, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 22 | Unknown 22 |
| Phase 1 | 3 | Unknown 3 |
| Phase 3 | 3 | Unknown 3 |
Follow Ascorbic Acid: new trials by email Literature Review of Ascorbic Acid trials Research Report on Ascorbic Acid
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Vitamin C on Postoperative Pulmonary Complications After Intracranial Tumor Surgery Ascorbic acid, Saline - Ascorbic Acid, Neurosurgical Procedures | Phase 2 | Unknown | Qianfoshan Hospital | 86 | 2024-06-01 | 2024-05-20 |
| Effect of Vitamin C Supplementation in Patients With Primary Hypothyroidism Vitamin C, Oral Rehydration Salt Formulations - Hypothyroidism, Primary Hypothyroidism | Phase 2 | Unknown | Dr Adnan Agha | 40 | 2023-11-01 | 2024-01-11 |
| Vitamin C to Quality of Life in Patients With Terminal Stage Pancreatic Cancer Ascorbate - Metastatic Pancreatic Cancer, Terminal Cancer | Phase 2 | Unknown | Fudan University | 20 | 2023-08-25 | 2024-06-06 |
| Efficacy of Megadose Vitamin C in Severe and Critical Ill COVID-19 Patients. Vitamin C, Placebo - Vitamin C, COVID-19 Pneumonia | Phase 2 / Phase 3 | Unknown | Zhujiang Hospital | 608 | 2023-01-13 | 2023-01-23 |
| Comparison Of Efficacy Of Combination Of TAM Formula Vs Kligman Formula For Melasma. TAM formula (hydroquinone 2%, tretinoin 0.05% and 5% vitamin C), Kligman formula (hydroquinone 4%, fluocinolone acetonide 0.01% and tretinoin 0.05%) - Melasma | Phase 2 | Unknown | Jinnah Postgraduate Medical Centre | 122 | 2022-08-01 | 2023-08-28 |
| Evaluation of Safety and Dosing of a Vitamin C Bundle for Sepsis Treatment in Africa Vitamin C, Vitamin B1 - Sepsis, Septic Shock | Phase 2 | Unknown | Liverpool School of Tropical Medicine | 60 | 2021-09-01 | 2021-09-08 |
| Preoperative IMRT With Concurrent High-dose Vitamin C and mFOLFOX6 in Locally Advanced Rectal Cancer Vitamin C - Rectal Cancer | Phase 2 | Unknown | Zhou Fuxiang | 60 | 2021-03-08 | 2021-03-17 |
| Ascorbic Acid to Prevent Postreperfusion Syndrome in Liver Transplantation Ascorbic acid, 0.9% Saline solution - Liver Transplantation, Postreperfusion Syndrome | Phase 2 | Unknown | Hospital Universitario Ramon y Cajal | 70 | 2020-11-17 | 2023-03-03 |
| Impact of Vitamin C on Biomarkers of Neurologic Injury in Survivors of Cardiac Arrest Vitamin C, Placebo - Heart Arrest, Out-Of-Hospital, Biomarkers | Phase 2 | Unknown | University Medical Centre Maribor | 150 | 2020-10-01 | 2020-09-24 |
| International ALLIANCE Study of Therapies to Prevent Progression of COVID-19 Vitamin C, Hydroxychloroquine, Azithromycin - COVID19 | Phase 2 | Unknown | National Institute of Integrative Medicine, Australia | 200 | 2020-09-09 | 2020-09-11 |
| High Dose Vitamin C Combined With Metformin in the Treatment of Malignant Tumors Vitamin C, Metformin - Hepatocellular Cancer, Pancreatic Cancer | Phase 2 | Unknown | Zhongnan Hospital | 30 | 2020-07-01 | 2023-09-28 |
| Pharmacologic Ascorbic Acid as an Activator of Lymphocyte Signaling for COVID-19 Treatment Ascorbic Acid - COVID-19 | Phase 2 | Unknown | Thomas Jefferson University | 66 | 2020-05-01 | 2020-05-05 |
| The Effectiveness of High-dose Intravenous Vitamin c With Very Low Carbohydrate Diet for Terminal Colon Cancer Patients Ascorbic Acid, Control group - Colon Cancer Stage Iv | Phase 1 / Phase 2 | Unknown | National Taiwan University Hospital | 40 | 2020-01-01 | 2019-07-29 |
| Vitamin C and Tyrosine Kinase Inhibitor in Lung Cancer Patients With Epidermal Growth Factor Receptor Mutations Vitamin C, Tyrosine kinase inhibitor - Carcinoma, Non-Small-Cell Lung | Phase 1 / Phase 2 | Unknown | Clifford Hospital, Guangzhou, China | 150 | 2018-12-05 | 2019-01-10 |
| Intravenous Ascorbic Acid Supplementation in Neoadjuvant Chemotherapy for Breast Cancer Ascorbic Acid, Placebos - Breast Cancer | Phase 1 / Phase 2 | Unknown | Academic Emergency County Hospital Sibiu | 30 | 2018-10-01 | 2018-06-27 |
| Oral Arsenic Trioxide for Newly Diagnosed Acute Promyelocytic Leukaemia Oral arsenic Trioxide, ATRA and ascorbic acid - Acute Promyelocytic Leukemia | Phase 2 | Unknown | The University of Hong Kong | 60 | 2018-08-15 | 2022-10-04 |
| Vitamin C as an Adjunct in Periodontal Treatment in Type 2 Diabetes Mellitus Patients Vitamin C 500 MG Oral Capsule, placebo - Diabetes Mellitus Type 2 With Hyperglycemia, Periodontitis | Phase 2 | Unknown | Mahidol University | 30 | 2017-08-30 | 2017-09-01 |
| Delivery of Inhibitors of Lysyl Oxidase (LysoLox) on Serial Angioplasty and Time to Restenosis Placebo, Ascorbic Acid, Cuprimine Oral Product - Arteriovenous Fistula Occlusion | Phase 2 | Unknown | Southeast Renal Research Institute | 30 | 2017-02-01 | 2017-09-11 |
| Trial of Vitamin C as Add on Therapy for Children With Idiopathic Epilepsy Vitamin C - Idiopathic Epilepsy | Phase 2 | Unknown | Ain Shams University | 60 | 2015-02-01 | 2015-02-24 |
| Role of Vitamin C to Augment Iron Chelation With DFP or DFX Vitamin C, Defriprone, deferisarox, deferiprone , deferesarox - Vitamin c, Thalassemia Major | Phase 2 / Phase 3 | Unknown | Ain Shams University | 50 | 2014-04-01 | 2014-03-11 |
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COVID-19 (3) · Colorectal Neoplasms (2) · Pancreatic Neoplasms (2) · Sepsis (2) · Acquired Immunodeficiency Syndrome (1) · Anemia (1) · Ascorbic Acid Deficiency (1) · Brain Injuries (1) · Breast Neoplasms (1) · Carcinoma, Non-Small-Cell Lung (1) · Colonic Neoplasms (1) · Heart Arrest (1) · Hypothyroidism (1) · Leukemia, Promyelocytic, Acute (1) · Liver Neoplasms (1)
Ain Shams University (2) · Academic Emergency County Hospital Sibiu (1) · Clifford Hospital, Guangzhou, China (1) · Dr Adnan Agha (1) · Fudan University (1) · Hospital Universitario Ramon y Cajal (1) · Jinnah Postgraduate Medical Centre (1) · Liverpool School of Tropical Medicine (1) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (1) · Mahidol University (1) · National Institute of Integrative Medicine, Australia (1) · National Taiwan University Hospital (1) · Qianfoshan Hospital (1) · Southeast Renal Research Institute (1) · Taichung Veterans General Hospital (1)
China (6) · Egypt (2) · Taiwan (2) · Australia (1) · Canada (1) · Hong Kong (1) · Pakistan (1) · Romania (1) · Slovenia (1) · Spain (1) · Thailand (1) · Uganda (1) · United Arab Emirates (1) · United States (1)
Adnan Agha (1) · Andrej Markota, MD, PhD, Assist. Prof. (1) · Chin-Ying Chen, MD, MHSc (1) · Dagan Coppock, M.D. (1) · Daniel Monti, M.D. (1) · Dong Wang, M.D (1) · Florin Grosu, MD,PhD (1) · Fuxiang Zhou, M.D (1) · Fuxiang Zhou, M.D. (1) · Guopei Luo, MD (1) · Harinder Singh Harry Gill, MBBS (1) · Iman A Elagouza, A Professor (1) · James A Tumlin, MD (1) · Junwen Ou, PhD (1) · Karin Ried, PhD (1)