88 completed, 30 recruiting, 14 not yet recruiting, 11 unknown. 139 Not applicable, 10 Phase 2, 6 Phase 1, 3 Phase 3, 2 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Mindfulness-based Stress Reduction Program for IBD Mindfulness based stress reduction, Active Control - Inflammatory Bowel Disease (Crohn&Amp;#39;s Disease and Ulcerative Colitis) | Not applicable | Not yet recruiting | Nova Scotia Health Authority | 70 | 2027-09-01 | 2026-09-08 |
| Developing and Piloting an Implementation Strategy for a Brief, Motivational Interviewing-based Lethal Means Safety Counseling Intervention in Primary Care Settings RAMP, Active control - Suicide Prevention | Not applicable | Not yet recruiting | VA Office of Research and Development | 50 | 2027-07-01 | 2025-11-25 |
| A Digitally Supported Outdoor Physical Activity Intervention for Mildly Frail Older Adults in Hong Kong OUTDOOR-FIT, Active Control - Physical Inactivity Frailty | Not applicable | Not yet recruiting | The Hong Kong Polytechnic University | 240 | 2027-02-01 | 2026-08-07 |
| Cognitive and Behavioral Approaches to Reduce Binge Eating and Excess Weight in Adolescents (Online) Cognitive-Behavioral Therapy for Adolescent Binge Eating, Lifestyle Behavioral Obesity Intervention, Active Control - Binge Eating, Overweight and Obesity | Not applicable | Not yet recruiting | Indiana University | 159 | 2026-11-01 | 2026-10-05 |
| Machine Learning Enabled Management of Behavioural and Psychological Symptoms of Dementia Intervention for Dementia Caregivers Active Control, Behavioral: Continue, Behavioral: Enhance human coaching - Dementia Caregiver | Not applicable | Not yet recruiting | Education University of Hong Kong | 550 | 2026-10-12 | 2026-10-05 |
| Dose-Response Structured Calf Muscle Pump Activation Strategies Versus Unsupervised Home Walks Dose-Response Structured CMP Activation, Active Control - Venous Ulcer of Leg | Not applicable | Not yet recruiting | MTI University | 80 | 2026-10-01 | 2026-08-13 |
| Mindfulness for Lonely Older Adults With Emigrant Children Intervention, Active Control - Loneliness, Sleep Quality | Not applicable | Not yet recruiting | Hong Kong Metropolitan University | 90 | 2026-10-01 | 2026-07-17 |
| Immediate Effects of Neuroathletic Training on Muscle Activity, Flexibility, and Ankle Mobility Single-Session Neuroathletic Training, Active Control - Hamstring Tightness | Not applicable | Completed | Ankara Yildirim Beyazıt University | 40 | 2026-09-26 | 2026-10-22 |
| Efficacy and Safety Study of Digital Cognitive Training and PCSK9 Inhibitor-Enhanced Lipid-lowering Strategy in Patients With Intracranial Atherosclerotic Stenosis: A 2x2 Factorial, Randomized, Parallel-Group, Multicenter Trial Rosuvastatin, Ezetimibe, Recaticimab - Intracranial Arteriosclerosis, Cognitive Impairment | Phase 4 | Not yet recruiting | Peking Union Medical College Hospital | 440 | 2026-09-17 | 2026-09-15 |
| Effects of Adapted Argentine Tango Training Frequency on Dual-Task Walking Distributed Adapted Argentine Tango Training, Concentrated Adapted Argentine Tango Training, Health Education and Low-Intensity Stretching - Motor-Cognitive Function, Dual-Task Walking | Not applicable | Not yet recruiting | Xi'an Medical University | 270 | 2026-08-29 | 2026-09-02 |
| AI-driven Personalized Exercise Feedback Program on Exercise Adherence in Traumatic Brain Injury AI-PEF, Theory-based digital exercise, Active Control - Traumatic Brain Injury, Exercise | Not applicable | Not yet recruiting | National Defense Medical Center, Taiwan | 125 | 2026-08-17 | 2026-09-10 |
| Testing Just-in-Time Adaptive Interventions (JITAIs) to Prevent Goal Disengagement in Response to Weight Regain JITAI Combined with psychological intervention, Active Control - Overweight or Obesity | Not applicable | Recruiting | ORI Community and Evaluation Services | 120 | 2026-07-14 | 2026-08-11 |
| The INICIO-Guatemala Study Nutri-INICIO, Mediational Intervention for Sensitizing Caregivers (MISC, Active Control - Development, Child | Not applicable | Recruiting | University of North Carolina, Chapel Hill | 400 | 2026-07-02 | 2026-07-24 |
| Reducing Firearm Suicide Among Veterans: Evaluating the Effectiveness of Peer-Delivered Lethal Means Counseling Peer Engagement and Exploration of Responsibility and Safety, Active Control - Suicide, Secure Firearm Storage | Phase 1 / Phase 2 | Not yet recruiting | VA Office of Research and Development | 100 | 2026-07-01 | 2026-03-12 |
| Developing and Testing a Machine Learning Enabled Mindfulness Intervention for Reducing Loneliness Among Hong Kong Chinese Older Adults Mindfulness - Continue, Mindfulness - Enhance human coaching, Mindfulness - Booster - Loneliness | Not applicable | Active not recruiting | Education University of Hong Kong | 250 | 2026-06-01 | 2026-09-14 |
| Acute Effect of Exergaming Based Sitting Tai Chi Exergaming based sitting Tai Chi, Seated Stretching - Healthy | Not applicable | Recruiting | Hong Kong Metropolitan University | 40 | 2026-06-01 | 2026-09-21 |
| Fall Risk Intervention for Stroke Fall Prevention Intervention, Active Control - Stroke | Not applicable | Recruiting | MGH Institute of Health Professions | 134 | 2026-04-09 | 2026-06-03 |
| Kidney Transplant Improvement Through New Exercise Training to Increase Capacity Exercise Rehabilitation Program with Physical Activity Tracker, Active control - Chronic Kidney Disease 5D, Chronic Kidney Disease Stage 5 | Not applicable | Recruiting | University of Pennsylvania | 60 | 2026-03-24 | 2026-05-06 |
| Effectiveness of an AI-Integrated Proactive Thought Control Intervention for Young Adults With Social Anxiety Disorder AI-Proactive thought control, Cognitive Behavior Therapy, Active Control - Social Anxiety Disorder (SAD) | Not applicable | Completed | Farah Shahzadi | 75 | 2026-03-14 | 2026-09-09 |
| Exercises for Rehabilitation of COgnition and Lifestyle Enhancement in Patients With Mild Cognitive Impairment Multimodal Group Cognitive Rehabilitation Intervention, Active Control - Mild Cognitive Impairment (MCI) | Not applicable | Recruiting | Casa di Cura IGEA | 40 | 2026-02-16 | 2026-04-08 |
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Cognitive Dysfunction (15) · Motor Activity (15) · Depression (14) · Anxiety Disorders (10) · Obesity (9) · Psychological Well-Being (8) · Sleep Initiation and Maintenance Disorders (6) · Attention Deficit Disorder with Hyperactivity (5) · Overweight (5) · Psychotic Disorders (5) · Chronic Pain (4) · Depressive Disorder, Major (4) · Diabetes Mellitus (4) · Diabetes Mellitus, Type 2 (4) · Alzheimer Disease (3)
The Hong Kong Polytechnic University (5) · Indiana University (4) · University of Pennsylvania (4) · VA Office of Research and Development (4) · University of Calgary (3) · University of California, San Francisco (3) · David Grant U.S. Air Force Medical Center (2) · Education University of Hong Kong (2) · Florida State University (2) · Harvard University (2) · Hong Kong Metropolitan University (2) · Loyola Marymount University (2) · Mesoblast, Ltd. (2) · National Defense Medical Center, Taiwan (2) · National University of Singapore (2)
United States (72) · Canada (12) · Hong Kong (10) · United Kingdom (6) · Spain (5) · Taiwan (4) · Australia (3) · Belgium (3) · Greece (3) · Switzerland (3) · Turkey (Türkiye) (3) · Brazil (2) · Bulgaria (2) · China (2) · France (2)
Cathy A. Alessi, MD (2) · Kee Lee Chou, PhD (2) · Thomas G Adams Jr, PhD (2) · Zenong Yin, PhD (2) · Alexandra C Hott, MD (1) · Amy K Connery, PsyD (1) · Amy Pinkham, PhD (1) · Amy S Pappert, MD (1) · Andrea T Kozak, PhD (1) · Arianna N LaCroix, PhD (1) · Arkers NR Wong (1) · Arkers Wong (1) · Arkers Wong, PhD (1) · Aron K Barbey, Ph.D. (1)
PMID 18948180, PMID 20643703, PMID 21450184, PMID 22617164, PMID 22654945, PMID 23730719, PMID 23834036, PMID 24773615, PMID 25879452, PMID 25914334, PMID 26369884, PMID 26744309, PMID 26808332, PMID 26859236, PMID 26892312, PMID 27070409, PMID 27608829, PMID 27784290, PMID 27813452, PMID 28364685, PMID 28446495, PMID 28768528, PMID 28825973, PMID 29101095, PMID 29351965, PMID 29451411, PMID 29908406, PMID 30275966, PMID 30291068, PMID 30373734, PMID 30554975, PMID 30617102, PMID 30711665, PMID 30819010, PMID 30868154, PMID 30958707, PMID 31125095, PMID 31583918, PMID 31821014, PMID 31856747, PMID 32131745, PMID 32513881, PMID 32627860, PMID 32714561, PMID 32773637, PMID 32938410, PMID 33609955, PMID 33650444, PMID 33962675, PMID 34099390
2019 (2), 1IK2CX002877-01A1 (1), 1IK2RD000503-01A2 (1), 2014 (1), 2017 (1), 2023 (1), I01HX003477 (1), K23HL159325 (1), K23MH118420 (1), K23NR018487 (1), P30AG048785 (1), R01AG045157 (1), R01AG050448 (1), R01AG061161 (1), R01AG065259 (1)