93 completed, 41 unknown, 14 recruiting, 12 terminated. 68 Phase 3, 59 Phase 2, 27 Phase 4, 21 Not applicable, 12 Phase 1.
Follow Acetylsalicylic acid: new trials by email Literature Review of Acetylsalicylic acid trials Research Report on Acetylsalicylic acid
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Immunoglobulin Plus Firsekibart in Patients With Kawasaki Disease IVIG, Aspirin, Firsekibart - Kawasaki Disease | Phase 2 / Phase 3 | Not yet recruiting | Children's Hospital of Fudan University | 90 | 2026-11-01 | 2026-10-22 |
| Can Aspirin Reduce the Risk of HCC in Cirrhosis: The AspiRe HCC Trial Low-dose aspirin, Placebo Comparator - Liver Cirrhosis | Phase 3 | Not yet recruiting | Curtin University | 890 | 2026-06-01 | 2026-04-14 |
| Aspirin Dosing in Pregnancy Aspirin - Preeclampsia Possible | Early Phase 1 | Recruiting | NYU Langone Health | 30 | 2026-04-27 | 2026-05-18 |
| ATILA Project: Aspirin Versus Tirofiban in Endovascular Treatment for Patients With Acute Ischemic Stroke Due to Tandem Lesion Tirofiban, Acetylsalicylic acid - Acute Ischemic Stroke | Phase 4 | Completed | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 240 | 2026-03-20 | 2026-04-03 |
| Aspirin 50mg vs 100mg Combined With P2Y12 Inhibitor After PCI Aspirin, P2Y12 inhibitor - Coronary Artery Disease, Acute Coronary Syndromes | Not applicable | Recruiting | Jilin University | 2640 | 2026-03-01 | 2026-10-01 |
| Hip Fracture Surgery Arterial and Venous Thrombotic Events Prevention rivaroxaban and ASA, Low-molecular weight heparin, Fondaparinux - Hip Fracture Surgery, Cardiovascular Prevention | Phase 3 | Not yet recruiting | McMaster University | 100 | 2025-12-01 | 2025-11-14 |
| APPLE: Aspirin to Prevent Pregnancy Loss and Preeclampsia Aspirin 162 mg, Aspirin 81mg - Pre-Eclampsia, Pregnancy Loss | Phase 3 | Recruiting | University of Pennsylvania | 1150 | 2024-06-12 | 2026-09-10 |
| Use of 81 vs 325mg of ASA in Treatment of BCVI Acetylsalicylic Acid - Carotid Artery Injuries, Traumatic Injury | Early Phase 1 | Unknown | London Health Sciences Centre | 40 | 2024-06-01 | 2024-04-25 |
| Perioperative Platelet Inhibition With Acetylsalicylic Acid in Patients With Resectable Tumors of the Pancreatic Head Acetylsalicylic acid, Placebo - Pancreatic Cancer Resectable | Phase 2 | Not yet recruiting | German Cancer Research Center | 170 | 2024-04-01 | 2023-11-13 |
| A Trial Investigating Lu AF28996 in Healthy Adult Participants Lu AF28996, Acetylsalicylic Acid, Mefenamic Acid - Healthy Participants | Phase 1 | Completed | H. Lundbeck A/S | 22 | 2024-02-27 | 2024-06-11 |
| Study of the Protective Effect of Low-dose Aspirin on Renal Function in Patients With Early Diabetic Nephropathy Acetylsalicylic Acid, Placebo - Diabetic Nephropathy Type 2 | Phase 2 / Phase 3 | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 355 | 2024-01-01 | 2023-10-05 |
| Ticagrelor Single Antiplatelet Therapy in Patients With High Risk of Bleeding After DCB for Coronary Small Vessel Disease Ticagrelor, Clopidogrel, Aspirin - Coronary Heart Disease | Phase 4 | Unknown | Fu Wai Hospital, Beijing, China | 292 | 2023-11-15 | 2023-10-18 |
| Anti-inflammatory Therapy for Recurrent In-stent Restenosis Colchicine, Prednisone, Aspirin - In-stent Restenosis | Phase 4 | Recruiting | Fu Wai Hospital, Beijing, China | 252 | 2023-10-30 | 2025-08-08 |
| Evaluation of Low Dose Colchicine and Ticagrelor in Prevention of Ischemic Stroke in Patients With Stroke Due to Atherosclerosis Colchicine 0.5 MG, Ticagrelor 90mg, Aspirin 75-300mg - Stroke, Stroke, Ischemic | Phase 3 | Recruiting | Assistance Publique - Hôpitaux de Paris | 2800 | 2023-05-17 | 2025-09-08 |
| Trial to Determine Effective Aspirin Dose in COPD Aspirin 81mg, Aspirin 162 mg, Aspirin 325mg - Pulmonary Disease, Chronic Obstructive | Phase 3 | Recruiting | Johns Hopkins University | 48 | 2023-05-16 | 2026-03-16 |
| LDA and LMWH vs LDA Alone in High-risk Patients for Preeclampsia Prevention Aspirin, Tinzaparin - Preeclampsia Severe, Toxemia Of Pregnancy | Phase 4 | Recruiting | Alexandra Hospital, Athens, Greece | 100 | 2023-01-18 | 2026-01-23 |
| Thromboelastography With Platelet Mapping to Guide Antiplatelet Therapy After Lower Extremity Revascularization Aspirin, Clopidogrel, Ticagrelor - Thrombosis, Arterial Occlusive Diseases | Not applicable | Active not recruiting | Massachusetts General Hospital | 144 | 2023-01-01 | 2026-10-13 |
| Treatment Preventive for Pre-eclampsia by Acetylsalicylic Acid in Women Who Underwent Frozen Embryo Transfer Acetylsalicylic acid - Embryo Transfer, Hypertension, Pregnancy Induced | Phase 3 | Recruiting | Centre Hospitalier Universitaire de Liege | 276 | 2022-10-25 | 2025-02-18 |
| To Assess the Efficacy and Safety of Dual Anticoagulants i.e. Rivaroxaban Plus Aspirin and Clopidogrel Plus Aspirin in Patients Suffering From an Acute Coronary Syndrome Rivaroxaban 2.5 Mg Oral Tablet, Clopidogrel tablet, Aspirin tablet - Acute Coronary Syndrome | Phase 4 | Unknown | Sarmad Zahoor | 90 | 2022-10-01 | 2022-10-10 |
| Molecular Effects of Aspirin & Metformin on Colonic Epithelium Aspirin tablet, Metformin, Aspirin and Metformin - Colorectal Cancer, Colorectal Neoplasms | Not applicable | Withdrawn | University of Edinburgh | 2022-08-01 | 2025-02-06 |
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Stroke (15) · Thrombosis (12) · Ischemic Stroke (11) · Colorectal Neoplasms (10) · Coronary Artery Disease (9) · Pre-Eclampsia (9) · Atrial Fibrillation (8) · Acute Coronary Syndrome (6) · Cardiovascular Diseases (6) · Colonic Neoplasms (6) · Peripheral Arterial Disease (6) · Venous Thromboembolism (6) · Mucocutaneous Lymph Node Syndrome (5) · Myocardial Infarction (5) · Prostatic Neoplasms (5)
National Cancer Institute (NCI) (9) · Bristol-Myers Squibb (3) · Children's Hospital of Fudan University (3) · Fu Wai Hospital, Beijing, China (3) · Population Health Research Institute (3) · Universidade Estadual Paulista Júlio de Mesquita Filho (3) · Vanderbilt University (3) · Xijing Hospital (3) · Abbott (2) · Aragon Institute of Health Sciences (2) · Assistance Publique - Hôpitaux de Paris (2) · Bayer (2) · Biogen (2) · Boehringer Ingelheim (2) · Copenhagen University Hospital, Rigshospitalet (2)
United States (51) · Canada (23) · China (21) · Italy (19) · Denmark (17) · Spain (17) · Switzerland (15) · Germany (14) · Netherlands (14) · France (13) · United Kingdom (13) · Belgium (12) · Brazil (11) · South Korea (10) · Australia (8)
Gang Zhao, M.D. (3) · Francesco Violi, MD (2) · Haiyan Qian, MD, PhD (2) · John Mascarenhas, MD (2) · Leslie Skeith, MD (2) · Marc Rodger, MD (2) · Mauro Santamaria, Professor (2) · Roopal Thakkar, MD (2) · Alan J Kivitz, MD (1) · Alessandro Rambaldi, MD (1) · Alfredo Perales, PhD (1) · Amit Oza (1)
PMID 35224730, PMID 36700520, PMID 37489818, PMID 40775758, PMID 1100130, PMID 11010931, PMID 11454256, PMID 15141377, PMID 15867308, PMID 16286167, PMID 16539843, PMID 16960170, PMID 16960171, PMID 17261652, PMID 17697815, PMID 17698822, PMID 18355656, PMID 18388038, PMID 18567918, PMID 18774340, PMID 19106084, PMID 19108880, PMID 19153091, PMID 19220726, PMID 19228706, PMID 19301936, PMID 19324253, PMID 19331435, PMID 19336502, PMID 19414633, PMID 19482214, PMID 19762550, PMID 19782922, PMID 20096533, PMID 20204386, PMID 20334810, PMID 20566953, PMID 2056896, PMID 20572767, PMID 20650435, PMID 20659762, PMID 20837828, PMID 20837893, PMID 20937093, PMID 20943705, PMID 20961243, PMID 21098354, PMID 21146637, PMID 21216739, PMID 21285990
2014 (5), 2015 (4), 2016 (3), 2017 (2), N01CN00031 (2), N01CN00034 (2), P01CA108671 (2), P30CA016672 (2), P30CA023074 (2), 2018 (1), 2023 (1), K01HL130625 (1), K23HL151758 (1), N01CN00035 (1), N01CN35000 (1)