9 completed, 8 unknown, 2 terminated. 19 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 19 | Completed 9, Unknown 8, Terminated 2 |
Follow 0.9% Normal Saline: new trials by email Literature Review of 0.9% Normal Saline trials Research Report on 0.9% Normal Saline
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Superior Hypogastric Nerve Plexus Block With Bupivacaine After Robotic Resection of Endometriosis Bupivacaine Hydrochloride, Normal saline - Endometriosis | Phase 4 | Unknown | Baylor College of Medicine | 60 | 2024-08-28 | 2025-08-18 |
| Combined Use of Naldebain® ER Injection and Precedex® After VATS PRECEDEX INJ★ 2ML, Normal saline - Acute Post Operative Pain, Chronic Post Operative Pain | Phase 4 | Unknown | Kaohsiung Medical University Chung-Ho Memorial Hospital | 70 | 2023-12-28 | 2023-12-19 |
| Comparison Between Ultrasound-Guided Genicular Nerve Phenol Neurolysis and Intra-articular Steroid Injections 6% aqueous phenol, MethylPREDNISolone 40 MG, Intraarticular Knee Placebo - Osteoarthritis, Knee, Chronic Knee Pain | Phase 4 | Unknown | University of Manitoba | 40 | 2023-10-20 | 2023-10-10 |
| Efficacy of Mouthwash in Reducing Salivary Carriage of COVID-19 0.5% Povidone Iodine, 0.12% Chlorhexidine Gluconate Mouth Rinse, 1% Hydrogen Peroxide - COVID-19 | Phase 4 | Unknown | Ohio State University | 60 | 2020-10-01 | 2020-10-27 |
| Effect of Anti-histamine in Prevention Systolic Hypotension After Protamine Chlorpheniramine and ranitidine, 0.9% Normal Saline - Protamine Adverse Reaction | Phase 4 | Completed | Mahidol University | 40 | 2018-09-05 | 2021-09-01 |
| Effect of Preoperative Ferric Carboxymaltose After Simultaneous Bilateral Total Knee Arthroplasty Ferric carboxymaltose, 0.9% Normal Saline - Postoperative Anemia, Knee Osteoarthritis | Phase 4 | Unknown | The Catholic University of Korea | 80 | 2018-06-11 | 2018-06-19 |
| Effect of Postoperative Ferric Carboxymaltose Ferric carboxymaltose, 0.9% Normal Saline - Postoperative Anemia, Knee Osteoarthritis | Phase 4 | Unknown | The Catholic University of Korea | 80 | 2018-06-11 | 2018-06-19 |
| Ketorolac Use in Pediatric Patients Undergoing Tonsillectomy Ketorolac Tromethamine, 0.9% Normal Saline - Analgesic Adverse Reaction | Phase 4 | Terminated | Albany Medical College | 214 | 2017-11-21 | 2024-10-15 |
| Efficacy of Multimodal Periarticular Injections in Operatively Treated Ankle Fractures Ropivacaine, Epinephrine, Morphine - Pain, Postoperative, Ankle Fractures | Phase 4 | Completed | University of Iowa | 100 | 2016-10-01 | 2023-12-15 |
| Comparison of Dexmedetomidine and Fentanyl to Prevent Hemodynamic Response to Skull Pins Application Dexmedetomidine, Fentanyl, 0.9% normal saline - Hemodynamic Response, Skull Pins Application | Phase 4 | Completed | Khon Kaen University | 60 | 2015-09-01 | 2020-08-20 |
| Comparison of Topical and Infusion Tranexamic Acid After Total Knee Arthroplasty Tranexamic Acid 5%,5ml/amp, rivaroxaban (10mg), 0.9% Normal Saline - Osteoarthritis, Knee | Phase 4 | Unknown | Chang Gung Memorial Hospital | 90 | 2015-06-01 | 2015-05-27 |
| Efficacy of Peri-Incisional Multimodal Drug Injection Following Operative Management of Femur Fractures Ropivacaine, Epinephrine, Morphine - Pain, Postoperative, Femur Fracture | Phase 4 | Completed | University of Iowa | 102 | 2015-05-01 | 2018-04-05 |
| The Effect of Thoracic Epidural Anesthesia With Different Block Level on Propofol Induction 1% lidocaine, 2% lidocaine, 0.9% normal saline - Target Controlled Infusion (TCI), Thoracic Epidural Anesthesia | Phase 4 | Completed | First Hospital of China Medical University | 45 | 2014-04-01 | 2014-08-29 |
| Trial Of Normal Saline Versus Ringer's Lactate In Paediatric Trauma Patients Normal Saline, Ringer's Lactate - Trauma | Phase 4 | Completed | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 50 | 2013-05-01 | 2018-11-06 |
| The Blood Saving Effect of Tranexamic Acid in Total Knee Arthroplasty With Rivaroxaban as Thromboprophylaxis Tranexamic Acid 5%,5ml/amp (intraoperative), Tranexamic Acid 5%,5ml/amp (3 hours after operation), 0.9% Normal Saline (intraoperative) - Osteoarthritis, Knee | Phase 4 | Completed | Chang Gung Memorial Hospital | 294 | 2012-08-01 | 2015-06-01 |
| The Effect of Dexmedetomidine on Emergence Agitation in Children Undergoing a Surgery Under Desflurane Anesthesia Dexmedetomidine, 0.9% Normal Saline - Psychomotor Agitation | Phase 4 | Unknown | Seoul National University Hospital | 116 | 2012-01-01 | 2012-04-16 |
| Intravenous (IV) Solutions for Dehydration in Children With Gastroenteritis multiple electrolyte solution, saline - Dehydration, Gastroenteritis | Phase 4 | Terminated | Baxter Healthcare Corporation | 100 | 2011-06-01 | 2018-04-26 |
| Local Infiltration With Bupivacaine to Increase Quality of Post-operative Pain Control in Total Knee Replacement 0.25% Bupivacaine, 0.9% normal saline - Pain, Postoperative, Arthropathy of Knee Joint | Phase 4 | Completed | Mahidol University | 60 | 2010-03-01 | 2011-06-02 |
| Transverse Abdominis Plane (TAP) Block After Cesarean Delivery 0.9% Normal Saline, 0.2% Ropivacaine, 0.5% Ropivacaine - Postoperative Pain, Pregnancy | Phase 4 | Completed | Northwestern University | 120 | 2010-01-01 | 2021-12-08 |
Pain, Postoperative (6) · Osteoarthritis, Knee (5) · Ankle Fractures (1) · COVID-19 (1) · Dehydration (1) · Endometriosis (1) · Femoral Fractures (1) · Gastroenteritis (1) · Obesity (1) · Pathologic Complete Response (1) · Postoperative Complications (1) · Psychomotor Agitation (1) · Wounds and Injuries (1)
Chang Gung Memorial Hospital (2) · Mahidol University (2) · The Catholic University of Korea (2) · University of Iowa (2) · Albany Medical College (1) · Baxter Healthcare Corporation (1) · Baylor College of Medicine (1) · First Hospital of China Medical University (1) · Kaohsiung Medical University Chung-Ho Memorial Hospital (1) · Khon Kaen University (1) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (1) · Northwestern University (1) · Ohio State University (1) · Seoul National University Hospital (1) · University of Manitoba (1)
United States (7) · Taiwan (3) · Thailand (3) · Canada (2) · China (1) · South Korea (1)
Jun-Wen Wang, MD (2) · Yong In, MD, PhD (2) · AhYoung Oh (1) · David L Hall, DDS (1) · David Walega, M.D. (1) · Douglas D Fraser, MD, PhD (1) · Drew Jones, MD (1) · Farzana Afroze, MD (1) · Gurinder S Sangha, MD (1) · Hung-Te Hsu, MD, PhD (1) · Javier Webar, MD (1) · Jun Wang, professor (1) · Keerati Chareancholvanich, MD (1) · Kyle Hancock, MD (1) · Michael C Willey, MD (1)