12 completed, 1 terminated. 11 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 11 | Completed 10, Terminated 1 |
| Phase 2 | 2 | Completed 2 |
Follow Whole Cell Pertussis: new trials by email Literature Review of Whole Cell Pertussis trials Research Report on Whole Cell Pertussis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study to Evaluate the Immunogenicity and Reactogenicity of a Booster Dose of GSK2036874A Vaccine in Healthy Toddlers GSK2036874A vaccine, Zilbrix™/Hib vaccine, Poliorix™ - Haemophilus Influenzae Type b, Tetanus | Phase 2 | Completed | GlaxoSmithKline | 312 | 2010-05-13 | 2019-10-01 |
| Non-inferiority of GSK Biologicals' DTPw-HBV/Hib Compared to Two Formulations of GSK Biologicals' DTPw-HBV/Hib Zilbrix-Hib, Tritanrix™-HepB/ Hiberix™ - Whole Cell Pertussis, Haemophilus Influenzae Type b | Phase 3 | Completed | GlaxoSmithKline | 300 | 2007-06-01 | 2017-08-18 |
| Assess Immunogenicity, Reactogenicity, Safety of a Booster of GSK Biologicals DTPw-HBV/Hib Kft Compared to DTPw-HBV/Hib DTPw-HBV/Hib Kft vaccine GSK323527A, Tritanrix™-HepB/Hiberix™ - Hepatitis B, Whole Cell Pertussis | Phase 3 | Completed | GlaxoSmithKline | 148 | 2006-06-01 | 2016-09-28 |
| Immuno & Safety Study With 2 Formulations of DTPw-HBV/HIB When Given at Birth With Hepatitis B at 2, 4 and 6 Mths.Age. Diphtheria, tetanus, pertussis, hepatitis B, Hib vaccine - Haemophilus Influenzae Type b, Diphtheria | Phase 3 | Terminated | GlaxoSmithKline | 288 | 2006-03-01 | 2016-10-07 |
| Lot-to-lot Consistency of Tritanrix™-HepB/Hib-MenAC & Its Non-inferiority vs Tritanrix™-HepB/Hiberix™ in Infants Hib-MenAC mixed with Tritanrix™-HepB - Tetanus, Hepatitis B | Phase 3 | Completed | GlaxoSmithKline | 800 | 2006-02-01 | 2016-10-07 |
| Response to GSK Biologicals' Tritanrix-HepB/Hib-MenAC Vacc (4th Dose) at 15-24m & Mencevax ACWY at 24-30m Tritanrix-HepB/Hib-MenAC, Mencevax ACWY, Tritanrix-HepB/Hiberix - Whole Cell Pertussis, Haemophilus Influenzae Type b | Phase 3 | Completed | GlaxoSmithKline | 617 | 2006-01-22 | 2020-02-20 |
| Safety Study of Tritanrix-HepB/Hib-MenAC, Tritanrix-HepB/Hiberix, and Mencevax ACWY Vaccines in Children Tritanrix-HepB/Hib-MenAC, Tritanrix-HepB/Hiberix, Mencevax-ACWY - Whole Cell Pertussis, Tetanus | Phase 3 | Completed | GlaxoSmithKline | 798 | 2005-06-16 | 2020-02-20 |
| Immune Memory of DTPw-HBV/Hib Vaccine Following Primary Vaccination, Immuno & Reacto of a Booster Dose Given in Infants Tritanrix™-HepB/Hiberix™ Kft., Tritanrix™-HepB/Hiberix™, Hiberix™ - Whole Cell Pertussis, Diphtheria | Phase 3 | Completed | GlaxoSmithKline | 745 | 2005-02-10 | 2018-06-06 |
| Immunogenicity & Safety Study of a Vaccine Against Meningitis in Infants (2,4,6 Months) After a Hepatitis B Birth Dose. DTPw-HBV/Hib-MenAC conjugate vaccine - Diphtheria, Hepatitis B | Phase 3 | Completed | GlaxoSmithKline | 1000 | 2004-08-01 | 2016-09-20 |
| Safety Study of a Vaccine Against Meningitis in Infants (2,4 & 6 Months Age) After a Birth Dose of Hepatitis B. Tritanrix-HepB/Meningitec conjugate vaccine, Tritanrix/Hiberix vaccine - Hepatitis B, Diphtheria | Phase 3 | Completed | GlaxoSmithKline | 500 | 2004-06-08 | 2018-08-15 |
| Assess if Immune Response of GSK Biologicals' Tritanrix™-HepB/Hib-MenAC Given Without or With Hepatitis B Vaccine at Birth is at Least as Good as Tritanrix™-HepB/Hiberix™ Without Hepatitis B Vaccine at Birth, When Given to Healthy Infants DTPw-HBV/Hib-MenAC conjugate vaccine - Haemophilus Influenzae Type b, Diphtheria | Phase 3 | Completed | GlaxoSmithKline | 996 | 2004-05-01 | 2016-09-16 |
| Safety Study of a Vaccine Against Meningitis in Infants ( 2,4 & 6 Months Age) After a Birth Dose of Hepatitis B. Tritanrix-HepB/Meningitec conjugate vaccine, Tritanrix/Hiberix vaccine - Diphtheria, Hepatitis B | Phase 3 | Completed | GlaxoSmithKline | 500 | 2003-12-11 | 2018-08-15 |
| A Study to Assess Antibody Persistence, Boostability & Safety in Previously Primed Subjects. DTPw-HBV/Hib-MenAC conjugate vaccine - Haemophilus Influenzae Type b, Tetanus | Phase 2 | Completed | GlaxoSmithKline | 450 | 2003-07-01 | 2016-09-09 |
Diphtheria (13) · Haemophilus Infections (13) · Hepatitis B (13) · Tetanus (13) · Whooping Cough (2)
Actinomycetales Infections (13) · Bacterial Infections (13) · Bacterial Infections and Mycoses (13) · Blood-Borne Infections (13) · Clostridium Infections (13) · Communicable Diseases (13) · Corynebacterium Infections (13) · DNA Virus Infections (13) · Digestive System Diseases (13) · Gram-Negative Bacterial Infections (13) · Gram-Positive Bacterial Infections (13) · Hepadnaviridae Infections (13) · Hepatitis (13) · Hepatitis, Viral, Human (13) · Infections (13)
Hiberix (2) · PsACWY vaccine (2) · Hepatitis B Vaccines (1) · HibTITER protein, Haemophilus influenzae (1) · Tetanus Toxoid (1) · Vaccines (1)
GlaxoSmithKline (13)
Philippines (6) · Thailand (5) · Argentina (1) · Dominican Republic (1) · India (1) · Nicaragua (1)
PMID 17716936, PMID 20950456, PMID 31307216
2016 (1)