3 recruiting. 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Recruiting 3 |
Follow Vascular Anomaly: new trials by email Literature Review of Vascular Anomaly trials Research Report on Vascular Anomaly
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| 24VA022; VATCH Alpelisib for TIE2/PIK3CA Pathway VAs alpelisib (BYL719) - Vascular Anomalies, Vascular Anomaly | Phase 2 | Recruiting | Children's Hospital of Philadelphia | 61 | 2025-08-27 | 2026-10-19 |
| 24VA021; VATCH Trametinib for Ras/MAPK Pathway VAs Trametinib - Ras/MAPK Pathway Vascular Anomalies, Vascular Anomalies | Phase 2 | Recruiting | Children's Hospital of Philadelphia | 45 | 2025-08-27 | 2026-10-19 |
| A Trial of Targeted Therapies for Patients With Slow-Flow or Fast-Flow Vascular Malformations Alpelisib, Mirdametinib - Slow-Flow Vascular Malformation, Fast-Flow Vascular Malformation | Phase 2 | Recruiting | Murdoch Childrens Research Institute | 50 | 2024-09-13 | 2026-05-05 |
Vascular Malformations (3) · Arteriovenous Malformations (1) · Hereditary Sensory and Autonomic Neuropathies (1) · Lymphangioma (1) · Lymphangioma, Cystic (1) · Lymphatic Abnormalities (1) · Skin Diseases, Vascular (1)
Cardiovascular Abnormalities (3) · Cardiovascular Diseases (3) · Congenital Abnormalities (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Genetic Diseases, Inborn (1) · Hemic and Lymphatic Diseases (1) · Heredodegenerative Disorders, Nervous System (1) · Lymphatic Diseases (1) · Neoplasm, Lymphatic Tissue (1) · Neoplasms (1) · Neoplasms by Histologic Type (1) · Nervous System Diseases (1) · Nervous System Malformations (1) · Neurodegenerative Diseases (1) · Neuromuscular Diseases (1)
Alpelisib (2) · mirdametinib (1) · trametinib (1)
Children's Hospital of Philadelphia (2) · Murdoch Childrens Research Institute (1)
United States (2) · Australia (1)
Lydia Pathmanathan, MBBS, FRACP. (1) · Stephen Luen, MBChB, FRACP. (1) · Tony Penington, MBBS, FRACS. (1)