95 completed, 14 unknown, 11 terminated, 8 withdrawn. 133 Phase 3, 18 Phase 2.
Follow Urinary Incontinence: new trials by email Literature Review of Urinary Incontinence trials Research Report on Urinary Incontinence
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight Orforglipron, Placebo - Urinary Incontinence,Stress | Phase 3 | Recruiting | Eli Lilly and Company | 1000 | 2025-09-30 | 2026-11-04 |
| COPPER: A Trial Evaluating Copper-based Products for Incontinence-associated Dermatitis Diaper with a copper-based product + usual care, Barrier product with common diaper - Incontinence-associated Dermatitis | Phase 2 / Phase 3 | Withdrawn | Hospital Israelita Albert Einstein | 2025-09-01 | 2026-01-12 | |
| Japanese Bridging Study of Autologous Muscle Derived Cells Compared to Placebo for Female Urinary Sphincter Repair(JPN1) AMDC-USR, Placebo - Stress Urinary Incontinence | Phase 3 | Withdrawn | Cook MyoSite | 2025-06-01 | 2024-08-27 | |
| Pivotal Study of Voro Urologic Scaffold Voro Urologic Scaffold - Radical Prostatectomy, Stress Urinary Incontinence (SUI) | Phase 3 | Active not recruiting | Levee Medical, Inc. | 266 | 2025-04-18 | 2026-09-30 |
| Efficacy of Solifenacin, Mirabegron and Combination Therapy in Children With Daytime Urinary Incontinence (BeDry) Solifenacin, Mirabegron - Urinary Incontinence in Children | Phase 3 | Recruiting | University of Aarhus | 236 | 2024-06-27 | 2026-06-08 |
| Examining the Effects of Intra-detrusor Botox at Time of HoLEP in Men With Overactive Bladder Symptoms OnabotulinumtoxinA - Urinary Incontinence, Overactive Bladder Syndrome | Phase 2 / Phase 3 | Active not recruiting | Northwestern University | 66 | 2023-07-13 | 2026-11-06 |
| BioDFence® G3 For Full Nerve-Sparing Robotic-Assisted Radical Prostatectomy BioDFence G3 - Prostate Cancer, Prostatectomy | Phase 3 | Withdrawn | AdventHealth | 2023-04-01 | 2023-06-29 | |
| Use of a Dual-agent Local Analgesic (Bupivacaine-meloxicam) for Abdominal Incisions in Patients Undergoing Retropubic Mid-urethral Sling Surgery Bupivacaine-Meloxicam - Stress Urinary Incontinence, Surgical Incision | Phase 3 | Completed | TriHealth Inc. | 148 | 2023-01-23 | 2024-11-22 |
| The Effect of Local Anesthetic Solution in the Bladder Prior to Botox Injections in the Bladder Alkalinized Lidocaine, Placebo Sodium Chloride 0.9% Inj - Urge Incontinence, Overactive Bladder | Phase 3 | Unknown | Herlev and Gentofte Hospital | 50 | 2022-09-12 | 2022-09-22 |
| Lidocaine for Pessary Check Pain Reduction Lidocaine Hcl 2% Jelly, Placebo Jelly - Pelvic Organ Prolapse, Stress Urinary Incontinence | Phase 3 | Completed | University of South Florida | 66 | 2022-09-08 | 2023-12-14 |
| Platelet-Rich Plasma for Stress Urinary Incontinence Platelet-rich plasma injection - Urinary Incontinence,Stress, Urinary Incontinence | Phase 3 | Completed | Annah J. Vollstedt | 50 | 2022-05-23 | 2024-08-29 |
| Platelet Rich Plasma in Women With Urinary Incontinence Platelet Rich Plasma Injections, Normal Saline Injections - Urinary Incontinence, Stress Urinary Incontinence | Phase 2 / Phase 3 | Unknown | National and Kapodistrian University of Athens | 50 | 2021-07-01 | 2021-11-09 |
| Testosterone Effects on Pelvic Floor Muscles Testosterone Enanthate, Placebo - Urinary Incontinence, Menopause | Phase 3 | Withdrawn | Brigham and Women's Hospital | 2021-01-01 | 2022-07-20 | |
| Sling vs Botox for Mixed Incontinence Botox® injection, Mid-urethral sling - Urinary Incontinence, Stress, Urinary Incontinence, Urge | Phase 3 | Completed | NICHD Pelvic Floor Disorders Network | 150 | 2020-06-08 | 2025-06-03 |
| Comparisons of the Impact of Duloxetine Versus Imipramine on Therapeutic Efficacy, Psychological Distress, Sexual Function, Urethral and Bladder Wall Structure and Blood Flow in Women With Stress Urinary Incontinence: a Randomized Controlled Study Duloxetine, Imipramine - Stress Urinary Incontinence | Phase 3 | Withdrawn | Far Eastern Memorial Hospital | 2020-05-31 | 2022-08-17 | |
| Efficacy and Safety of Gefapixant (MK-7264) in Women With Chronic Cough and Stress Urinary Incontinence (MK-7264-042) Gefapixant, Placebo - Chronic Cough | Phase 3 | Completed | Merck Sharp & Dohme LLC | 376 | 2020-05-10 | 2024-11-05 |
| Vaginal Prolapse Surgery Accompanied by Mid Urethral Sling Versus no Sling for Reduction of Postoperative Incontinence Retro pubic sling - Stress Urinary Incontinence, Vaginal Hysterectomy | Phase 2 / Phase 3 | Unknown | B.P. Koirala Institute of Health Sciences | 56 | 2020-01-01 | 2020-02-05 |
| tDCS and Female Urinary Incontinence Real transcranial direct current stimulation + therapeutic exercises for urinary incontinence, Sham transcranial direct current stimulation + therapeutic exercises for urinary incontinence - Urinary Incontinence | Phase 2 / Phase 3 | Completed | Universidade Federal do Piauí | 60 | 2019-11-14 | 2023-11-28 |
| Chlorhexidine vs. Iodine for Vaginal Preparation in Urogynecologic Procedures Vaginal scrub, to be applied vaginally and perineally immediately prior to surgery. - Pelvic Organ Prolapse, Urinary Incontinence | Phase 3 | Completed | University of New Mexico | 137 | 2019-07-15 | 2023-07-10 |
| Autologous Muscle Derived Cells Compared to Placebo for Urinary Sphincter Repair in Post-surgical Female Stress Incontinence AMDC-USR (iltamiocel), Placebo - Stress Urinary Incontinence | Phase 3 | Active not recruiting | Cook MyoSite | 96 | 2019-04-23 | 2026-10-21 |
Showing 20 of 133. Sign in to see all of them.
Urinary Incontinence, Stress (55) · Urinary Bladder, Overactive (42) · Urinary Incontinence, Urge (26) · Urologic Diseases (8) · Lower Urinary Tract Symptoms (6) · Pelvic Organ Prolapse (6) · Prostatic Neoplasms (5) · Nocturia (4) · Urinary Tract Infections (3) · Nocturnal Enuresis (2) · Parkinson Disease (2) · Pelvic Floor Disorders (2) · Urinary Bladder Diseases (2) · Urinary Bladder, Neurogenic (2)
Female Urogenital Diseases (133) · Female Urogenital Diseases and Pregnancy Complications (133) · Male Urogenital Diseases (133) · Pathological Conditions, Signs and Symptoms (133) · Urination Disorders (133) · Urogenital Diseases (133) · Urological Manifestations (133) · Signs and Symptoms (132) · Lower Urinary Tract Symptoms (127) · Urologic Diseases (125) · Urinary Bladder Diseases (41) · Genital Diseases (10) · Neoplasms by Site (7) · Genital Diseases, Male (6)
Botulinum Toxins, Type A (16) · mirabegron (14) · Duloxetine Hydrochloride (13) · Tolterodine Tartrate (11) · Solifenacin Succinate (10) · oxybutynin (7) · Suburethral Slings (5) · propiverine (3) · Behavior Therapy (2) · Exercise Therapy (2) · N-(4-((5-(hydroxy(phenyl)methyl)pyrrolidin-2-yl)methyl)phenyl)-4-oxo-4,6,7,8-tetrahydropyrrolo(1,2-a)pyrimidine-6-carboxamide (2) · Saline Solution (2) · Surgical Procedures, Operative (2) · abobotulinumtoxinA (2) · ritobegron ethyl (2)
Eli Lilly and Company (12) · Astellas Pharma Inc (7) · Allergan (6) · NICHD Pelvic Floor Disorders Network (5) · Alza Corporation, DE, USA (4) · Cook MyoSite (4) · Copenhagen University Hospital at Herlev (4) · University of Michigan (4) · Hadassah Medical Organization (3) · APOGEPHA Arzneimittel GmbH (2) · Ain Shams University (2) · Astellas Pharma Europe B.V. (2) · Astellas Pharma Europe Ltd. (2) · CHU de Quebec-Universite Laval (2) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (2)
United States (59) · Canada (23) · United Kingdom (21) · Germany (17) · Czechia (15) · Italy (15) · Poland (15) · Belgium (14) · Denmark (13) · France (13) · Russia (11) · Spain (11) · Finland (8) · Hungary (8) · Netherlands (8)
Melissa Kaufman, M.D., Ph.D. (3) · Carolyn M Sampselle, PhD,RNC,FAAN (2) · Linda Brubaker, MD (2) · Matthew D Barber, MD, MHS (2) · Mikkel Fode, MD (2) · Yasuhiro Omori (2)
PMID 37160401, PMID 37888839, PMID 24246044, PMID 32378735, PMID 37811598, PMID 21344495, PMID 33620895, PMID 35400537, PMID 10925088, PMID 11176403, PMID 11857671, PMID 12612489, PMID 12790869, PMID 12894267, PMID 12934777, PMID 14625427, PMID 14767293, PMID 15586150, PMID 16237512, PMID 16282227, PMID 16611949, PMID 16868693, PMID 16897749, PMID 17197581, PMID 17228060, PMID 17336819, PMID 17385940, PMID 18060963, PMID 18060965, PMID 18185903, PMID 18221532, PMID 18310363, PMID 18455536, PMID 18499184, PMID 18502028, PMID 18591307, PMID 18656053, PMID 18722933, PMID 18845288, PMID 18976976, PMID 19183825, PMID 19233423, PMID 19375574, PMID 19625327, PMID 19701041, PMID 19929591, PMID 19941278, PMID 20093904, PMID 20171668, PMID 20177294
U10HD041261 (3), U10HD041267 (3), 2015 (2), 2017 (2), R01NR007618 (2), U01HD069031 (2), U10HD041250 (2), U10HD041263 (2), U10HD054214 (2), U10HD054215 (2), 2008 (1), 2014 (1), 2019 (1), 2025 (1), R01NR004007 (1)