9 completed. 9 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 9 |
| Phase 1 | 2 | Completed 2 |
Follow T-cell Large Granular Lymphocyte Leukemia: new trials by email Literature Review of T-cell Large Granular Lymphocyte Leukemia trials Research Report on T-cell Large Granular Lymphocyte Leukemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Donor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies therapeutic allogeneic lymphocytes, laboratory biomarker analysis - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Phase 2 | Completed | University of Chicago | 77 | 2013-04-04 | 2019-08-07 |
| Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies fludarabine phosphate, melphalan, total-body irradiation - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Roswell Park Cancer Institute | 94 | 2012-02-28 | 2019-09-24 |
| A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies Fludarabine, Busulfan, Total Body Irradiation (TBI) - Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission | Phase 2 | Completed | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 40 | 2011-08-04 | 2026-04-15 |
| Study of Akt Inhibitor MK2206 in Patients With Relapsed Lymphoma Akt inhibitor MK2206, laboratory biomarker analysis - Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma | Phase 2 | Completed | National Cancer Institute (NCI) | 60 | 2010-12-01 | 2020-11-04 |
| Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies double-unit umbilical cord blood transplantation, cytogenetic analysis, bone marrow aspiration - Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Case Comprehensive Cancer Center | 14 | 2007-09-01 | 2019-01-23 |
| Fludarabine Phosphate, Radiation Therapy, and Rituximab in Treating Patients Who Are Undergoing Donor Stem Cell Transplant Followed by Rituximab for High-Risk Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Allogeneic Hematopoietic Stem Cell Transplantation, Cyclosporine, Fludarabine Phosphate - Chronic Lymphocytic Leukemia, Prolymphocytic Leukemia | Phase 2 | Completed | Fred Hutchinson Cancer Center | 66 | 2004-12-01 | 2019-07-11 |
| Mycophenolate Mofetil and Cyclosporine in Reducing Graft-Versus-Host Disease in Patients With Hematologic Malignancies or Metastatic Kidney Cancer Undergoing Donor Stem Cell Transplant fludarabine phosphate, total-body irradiation, nonmyeloablative allogeneic hematopoietic stem cell transplantation - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 1 / Phase 2 | Completed | Fred Hutchinson Cancer Center | 37 | 2003-09-01 | 2020-01-18 |
| Alemtuzumab, Fludarabine Phosphate, and Low-Dose Total Body Irradiation Before Donor Stem Cell Transplantation in Treating Patients With Hematological Malignancies alemtuzumab, fludarabine phosphate, total-body irradiation - Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q) | Phase 2 | Completed | Fred Hutchinson Cancer Center | 60 | 2001-11-01 | 2020-01-29 |
| Fludarabine Phosphate, Low-Dose Total-Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine, Mycophenolate Mofetil, Donor Lymphocyte Infusion in Treating Patients With Hematopoietic Cancer total-body irradiation, fludarabine phosphate, cyclosporine - Acute Undifferentiated Leukemia, Adult Nasal Type Extranodal NK/T-cell Lymphoma | Phase 1 / Phase 2 | Completed | Fred Hutchinson Cancer Center | 21 | 2000-05-01 | 2020-01-21 |
Leukemia, Large Granular Lymphocytic (9) · Leukemia, Lymphocytic, Chronic, B-Cell (9) · Lymphoma, B-Cell, Marginal Zone (8) · Lymphoma, Extranodal NK-T-Cell (8) · Lymphoma, Follicular (8) · Lymphoma, Non-Hodgkin (8) · Lymphoma, T-Cell, Cutaneous (8) · Mycosis Fungoides (8) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (8) · Sezary Syndrome (8) · Waldenstrom Macroglobulinemia (8) · Hodgkin Disease (7) · Leukemia, Hairy Cell (7) · Leukemia, Myeloid, Acute (7) · Lymphoma, Large B-Cell, Diffuse (7)
Chronic Disease (9) · Disease Attributes (9) · Hematologic Diseases (9) · Hemic and Lymphatic Diseases (9) · Immune System Diseases (9) · Immunoproliferative Disorders (9) · Leukemia (9) · Leukemia, B-Cell (9) · Leukemia, Lymphoid (9) · Leukemia, T-Cell (9) · Lymphatic Diseases (9) · Lymphoproliferative Disorders (9) · Neoplasms (9) · Neoplasms by Histologic Type (9) · Pathologic Processes (9)
Mycophenolic Acid (7) · Peripheral Blood Stem Cell Transplantation (6) · Whole-Body Irradiation (6) · fludarabine phosphate (6) · Cyclosporine (5) · Busulfan (2) · Cyclophosphamide (2) · Cyclosporins (2) · Tacrolimus (2) · Alemtuzumab (1) · Antilymphocyte Serum (1) · Cytogenetic Analysis (1) · Flow Cytometry (1) · In Situ Hybridization, Fluorescence (1) · MK 2206 (1)
Fred Hutchinson Cancer Center (4) · Case Comprehensive Cancer Center (1) · National Cancer Institute (NCI) (1) · Roswell Park Cancer Institute (1) · Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University (1) · University of Chicago (1)
United States (9) · Italy (4) · Denmark (1) · Germany (1)
Brenda Sandmaier (2) · Brenda Cooper, MD (1) · David Maloney (1) · George Chen (1) · Hongtao Liu (1) · Mohamed Sorror (1) · Usama Gergis, MD (1) · Yasuhiro Oki (1)
PMID 32499241, PMID 19900571, PMID 26213141
P30CA015704 (4), P01CA018029 (3), N01CM00039 (1), N01CM62202 (1), P01CA078902 (1), P30CA016672 (1)