1 available, 1 completed, 1 not yet recruiting, 1 recruiting. 2 Phase 1, 2 Phase 2, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Completed 1, Not yet recruiting 1 |
| Phase 2 | 2 | Completed 1, Terminated 1 |
| Not applicable | 1 | Recruiting 1 |
Follow Systemic Sclerosis Pulmonary: new trials by email Literature Review of Systemic Sclerosis Pulmonary trials Research Report on Systemic Sclerosis Pulmonary
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| C-CAR168, an Autologous Anti-CD20/BCMA Chimeric Antigen Receptor T-Cell Therapy, in Participants With Systemic Sclerosis (SSc) Refractory to Standard Therapy C-CAR168 - Systemic Sclerosis (SSc), Systemic Sclerosis | Phase 1 | Not yet recruiting | AbelZeta Inc. | 12 | 2027-03-01 | 2026-10-13 |
| Home Based Clinical Management of Interstitial Lung Disease in Systemic Rheumatic Diseases A home monitoring strategy with event driven management - Interstitial Lung Disease with Progressive Fibrotic Phenotype in Diseases Classified Elsewhere, Systemic Sclerosis Pulmonary | Not applicable | Recruiting | Oslo University Hospital | 218 | 2024-12-16 | 2024-12-19 |
| Infusion of Allogeneic Stromal Mesenchymal Stem Cells From Wharton´s Jelly in Patients With Diffuse Cutaneous Systemic Sclerosis With Refractory Pulmonary Involvement to Treatment Mesenchymal Stem Cells from Wharton´s jelly - Systemic Sclerosis Pulmonary, Pulmonary Hypertension | Phase 1 / Phase 2 | Completed | Fundación Neumologica Colombiana | 1 | 2024-05-15 | 2026-04-21 |
| A Study to Evaluate the Safety and Tolerability of Oral Ixazomib in Scleroderma-related Lung Disease Patients Ixazomib - Systemic Sclerosis, Scleroderma | Phase 2 | Terminated | Michael M. Pham | 4 | 2021-04-28 | 2025-04-06 |
| Infusion of Allogeneic Mesenchymal Stem Cells in Patients With Diffuse Cutaneous Systemic Sclerosis With Refractory Pulmonary Involvement Mesenchymal Stem Cells from Wharton ́s jellyintravenous infusion of Mesenchymal Stem Cells from Wharton ́s jelly - Systemic Sclerosis Pulmonary, Pulmonary Hypertension | Available | Universidad de la Sabana | 2024-04-08 |
Scleroderma, Systemic (5) · Pulmonary Fibrosis (4) · Hypertension, Pulmonary (2) · Lung Diseases, Interstitial (2) · Scleroderma, Diffuse (2) · Arthritis, Rheumatoid (1) · Autoimmune Diseases (1) · Connective Tissue Diseases (1) · Dermatomyositis (1) · Rheumatic Diseases (1)
Skin Diseases (5) · Skin and Connective Tissue Diseases (5) · Connective Tissue Diseases (4) · Fibrosis (4) · Lung Diseases (4) · Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Respiratory Tract Diseases (4) · Cardiovascular Diseases (2) · Hypertension (2) · Immune System Diseases (2) · Lung Diseases, Interstitial (2) · Vascular Diseases (2) · Arthritis (1) · Autoimmune Diseases (1)
ixazomib (1)
AbelZeta Inc. (1) · Fundación Neumologica Colombiana (1) · Michael M. Pham (1) · Oslo University Hospital (1) · Universidad de la Sabana (1)
Colombia (2) · United States (2) · Norway (1)
John Londono, MD,PhD (2) · Anna-Maria Hoffmann-Vold, MD, PhD (1) · Michael Pham, MD (1) · Yihong Yao, PhD (1)