3 completed, 3 recruiting, 2 terminated, 1 suspended. 4 Phase 1, 2 Phase 2, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 2, Recruiting 2 |
| Phase 2 | 2 | Recruiting 1, Terminated 1 |
| Not applicable | 1 | Terminated 1 |
Follow Stage IVB Cervical Cancer AJCC v8: new trials by email Literature Review of Stage IVB Cervical Cancer AJCC v8 trials Research Report on Stage IVB Cervical Cancer AJCC v8
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors Cyclophosphamide, Neoantigen Peptide Vaccine, Pembrolizumab - Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | Phase 1 / Phase 2 | Recruiting | Mayo Clinic | 138 | 2022-03-31 | 2026-08-20 |
| Remote Telemonitoring of Patient-Generated Physiologic Health Data and Patient-Reported Outcomes Patient Monitoring, Questionnaire Administration - Clinical Stage 0 Esophageal Adenocarcinoma AJCC v8, Clinical Stage 0 Esophageal Squamous Cell Carcinoma AJCC v8 | Completed | City of Hope Medical Center | 22 | 2020-08-11 | 2026-10-14 | |
| Paclitaxel Therapeutic Drug Monitoring in Cancer Patients Blood draws, QLQ-CIPN20 Survey, PR-CTCAE Survey - Solid Tumor, Adult, Metastatic Nonsmall Cell Lung Cancer | Suspended | Wake Forest University Health Sciences | 55 | 2019-11-11 | 2026-08-13 | |
| Talazoparib and Radiation Therapy in Treating Patients With Locally Recurrent Gynecologic Cancers Quality-of-Life Assessment, Radiation Therapy, Talazoparib - Malignant Female Reproductive System Neoplasm, Recurrent Cervical Carcinoma | Phase 1 | Recruiting | M.D. Anderson Cancer Center | 24 | 2019-09-26 | 2026-03-11 |
| DNA Plasmid-encoding Interleukin-12/HPV DNA Plasmids Therapeutic Vaccine INO-3112 and Durvalumab in Treating Patients With Recurrent or Metastatic Human Papillomavirus Associated Cancers DNA Plasmid-encoding Interleukin-12/HPV DNA Plasmids Therapeutic Vaccine MEDI0457, Durvalumab - Human Papillomavirus-16 Positive, Human Papillomavirus-18 Positive | Phase 2 | Terminated | M.D. Anderson Cancer Center | 41 | 2018-11-14 | 2024-07-09 |
| Nivolumab With or Without Ipilimumab in Treating Patients With Recurrent or High Grade Gynecologic Cancer With Metastatic Peritoneal Carcinomatosis Ipilimumab, Laboratory Biomarker Analysis, Nivolumab - Malignant Peritoneal Neoplasm, Malignant Retroperitoneal Neoplasm | Phase 1 | Completed | M.D. Anderson Cancer Center | 26 | 2018-09-21 | 2025-05-22 |
| Stereotactic Body Radiation Therapy, Tremelimumab and Durvalumab in Treating Participants With Recurrent or Metastatic Cervical, Vaginal, or Vulvar Cancers Durvalumab, Laboratory Biomarker Analysis, Stereotactic Radiosurgery - Advanced Cervical Adenocarcinoma, Advanced Vaginal Carcinoma | Phase 1 | Completed | M.D. Anderson Cancer Center | 20 | 2018-07-18 | 2023-09-13 |
| Biospecimen Collection and Testing for the Prevalence of Anal Dysplasia and Anal Cancer in Patients With Cervical, Vaginal and Vulvar Dysplasia and Cancer Biospecimen Collection, Laboratory Biomarker Analysis - Cervical Adenocarcinoma, Cervical Adenocarcinoma In Situ | Not applicable | Terminated | M.D. Anderson Cancer Center | 409 | 2014-10-27 | 2025-07-14 |
| Establishing a Tumor Registry for Patients With Neuroendocrine Carcinoma of the Cervix Follow-Up, Medical Chart Review - Cervical Large Cell Neuroendocrine Carcinoma, Cervical Neuroendocrine Carcinoma | Recruiting | M.D. Anderson Cancer Center | 750 | 2013-05-16 | 2026-09-14 |
Uterine Cervical Neoplasms (9) · Ovarian Neoplasms (4) · Vaginal Neoplasms (4) · Vulvar Neoplasms (4) · Endometrial Neoplasms (3) · Carcinoma, Non-Small-Cell Lung (2) · Carcinoma, Renal Cell (2) · Fallopian Tube Neoplasms (2) · Lung Neoplasms (2) · Neoplasm Metastasis (2) · Neoplasms (2) · Anal Canal Carcinoma (1) · Anus Neoplasms (1) · Breast Neoplasms (1) · Carcinoma, Hepatocellular (1)
Female Urogenital Diseases (9) · Female Urogenital Diseases and Pregnancy Complications (9) · Genital Diseases (9) · Genital Diseases, Female (9) · Genital Neoplasms, Female (9) · Neoplasms by Site (9) · Urogenital Diseases (9) · Uterine Cervical Diseases (9) · Uterine Diseases (9) · Urogenital Neoplasms (8) · Uterine Neoplasms (8) · Neoplasms (7) · Adnexal Diseases (4) · Digestive System Diseases (4) · Digestive System Neoplasms (4)
Immunoglobulin G (3) · Disulfides (2) · durvalumab (2) · Biopsy (1) · Blood Specimen Collection (1) · CTLA-4 Antigen (1) · Chromatin Immunoprecipitation Sequencing (1) · Colony-Stimulating Factors (1) · Cyclophosphamide (1) · Follow-Up Studies (1) · Ipilimumab (1) · MEDI0457 (1) · Magnetic Resonance Spectroscopy (1) · Nivolumab (1) · Pharmacogenomic Variants (1)
M.D. Anderson Cancer Center (6) · City of Hope Medical Center (1) · Mayo Clinic (1) · Wake Forest University Health Sciences (1)
United States (9)
Lilie L Lin (2) · Amir A Jazaeri (1) · Kathleen Schmeler (1) · Laleh Melstrom (1) · Larissa A. Meyer (1) · Michael M Frumovitz (1) · Roy Strowd, MD (1) · Yanyan Lou, MD, PhD (1)
P30CA012197 (1), P30CA033572 (1)