27 completed, 9 unknown, 6 terminated, 5 withdrawn. 24 Phase 2, 17 Phase 1, 7 Phase 3, 4 Not applicable.
Follow Squamous Cell Lung Cancer: new trials by email Literature Review of Squamous Cell Lung Cancer trials Research Report on Squamous Cell Lung Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Trial of a Personalized and Adaptive Neoantigen Dose-Adjusted Vaccine Concurrently With Pembrolizumab PANDA-VAC, Pembrolizumab - Squamous Cell Lung Cancer, Squamous Non-small Cell Lung Cancer | Phase 1 | Suspended | UNC Lineberger Comprehensive Cancer Center | 6 | 2027-05-20 | 2026-04-23 |
| Phase Ib Study of Oral R01 Monotherapy in Advanced Solid Tumors R01 - Squamous Cell Lung Cancer, Gastric Cancer | Phase 1 | Not yet recruiting | Beijing Anjianxi Bio-Medical Technology Co., Ltd. | 18 | 2026-09-01 | 2026-09-08 |
| Phase II Study of Platinum (Cisplatin/Carboplatin)and Polymeric Micelles Paclitaxel(Pm-Pac) With Ivonescimab in First Line Metastatic Squamous NSCLC. Ivonescimab 20mg/kg intravenous every 3 weeks - Squamous Cell Lung Cancer | Phase 2 | Not yet recruiting | Jiangsu Cancer Institute & Hospital | 38 | 2025-06-01 | 2025-06-08 |
| An Phase I Trial of a CAR T-cell Infusion C-CAR031 in Participants With GPC3+ Advanced/Metastatic Squamous Cell Lung Cancer C-CAR031 - Squamous Cell Lung Cancer | Phase 1 | Recruiting | Shanghai AbelZeta Ltd. | 24 | 2024-12-25 | 2026-03-03 |
| A Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of TT125-802 in Subjects With Advanced Solid Tumors TT125-802 - Advanced Solid Tumor, Adult Solid Tumor | Phase 1 | Completed | TOLREMO therapeutics AG | 45 | 2023-11-07 | 2026-07-07 |
| CISH Inactivated TILs in the Treatment of NSCLC Fludarabine, Cyclophosphamide, CISH Inactivated TIL - Carcinoma, Non-Small-Cell Lung, Metastatic Non Small Cell Lung Cancer | Phase 1 / Phase 2 | Withdrawn | Intima Bioscience, Inc. | 2023-02-01 | 2026-02-23 | |
| A Study of ZEN003694 in People With Squamous Cell Lung Cancer ZEN003694 - Squamous Cell Lung Cancer | Phase 2 | Recruiting | Memorial Sloan Kettering Cancer Center | 13 | 2022-11-01 | 2026-09-23 |
| Long-Term Follow-up Study of Subjects Treated With Autologous T Cells Using the Sleeping Beauty System to Express TCRs Neoantigen specific TCR-T cell drug product - Gynecologic Cancer, Colorectal Cancer | Completed | Alaunos Therapeutics | 8 | 2022-10-07 | 2026-10-15 | |
| APOLLO 11, Consortium of Italian Centers Involved in Treatment of Patients With Lung Cancer Treated With Innovative Therapies: Real World Data and Translational Reaserch NSCLC, Cancer | Recruiting | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | 1200 | 2022-10-01 | 2023-10-23 | |
| Phase I/II Study of Autologous T Cells to Express T-Cell Receptors (TCRs) in Subjects With Solid Tumors Neoantigen specific TCR-T cell drug product, Aldesleukin (IL-2) - Gynecologic Cancer, Colorectal Cancer | Phase 1 / Phase 2 | Terminated | Alaunos Therapeutics | 8 | 2022-04-04 | 2025-11-10 |
| The Therapeutic Effect of Immunotherapy in Patients With Advanced Lung Squamous Carcinoma Efficacy observation - Squamous Cell Lung Cancer | Enrolling by invitation | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 1000 | 2021-01-01 | 2024-12-12 | |
| Efficacy of Immunotherapy Plus a Drug in Patients With Progressive Advanced Mucosal Cancer of Different Locations pembrolizumab; vorinostat - Squamous Cell Lung Cancer, Vulvar Cancer | Phase 2 | Completed | UNICANCER | 112 | 2020-10-28 | 2025-02-19 |
| Therapeutic ResistAnce and Clonal Evolution Assessed With Liquid Biopsy in ICIs Treated NSCLC Patients Observation - Lung Neoplasms, Lung Cancer, Nonsmall Cell | Completed | Geneplus-Beijing Co. Ltd. | 252 | 2020-07-01 | 2026-06-29 | |
| Prevalence of EGFR Mutations in epidermoïd Bronchopulmonary Cancers in Réunion Island EGFR mutation - Squamous Cell Lung Cancer | Completed | Centre Hospitalier Universitaire de la Réunion | 60 | 2020-02-24 | 2023-01-10 | |
| Genetic Predictors of Efficiency and Safety of ICIs in Patients With Different Malignancies (ICIPRESIST-0519) Genetic tests of the available tumor and plasma samples - Melanoma, Squamous Cell Lung Cancer | Unknown | Russian Academy of Medical Sciences | 350 | 2019-06-15 | 2021-12-28 | |
| FGFR Inhibitor in FGFR Dysregulated Cancer ERDAFITINIB - Lung Cancer, NSCLC | Phase 2 | Terminated | Lung Cancer Group Cologne | 22 | 2019-03-25 | 2023-06-09 |
| A Study of Anti-PD-1 AK105 in Patients With Metastatic Squamous Non-small Cell Lung Cancer AK105, Paclitaxel, Carboplatin - Lung Cancer Non-small Cell Stage IV, Squamous Cell Lung Cancer | Phase 3 | Completed | Akeso | 350 | 2018-12-20 | 2024-04-03 |
| Photodynamic Therapy for the Prevention of Lung Cancer Photodynamic Therapy (PDT) - Squamous Cell Lung Cancer, Lung Cancer | Phase 2 / Phase 3 | Withdrawn | University College, London | 2018-09-01 | 2019-02-01 | |
| Necitumumab in the Neoadjuvant Setting With Gemcitabine in Surgically Resectable - 14X-US-I001 Necitumumab-Gemcitabine-Cisplatin, Evaluation to determine if patient is a candidate to proceeed with surgical resection or not - Squamous Cell Lung Cancer | Phase 2 | Terminated | Montefiore Medical Center | 1 | 2018-05-29 | 2020-03-18 |
| Exhaled Breath Particles in Lung Cancer EBPcollected using the PExA device. - Lung Cancer, Non-small Cell Lung Cancer | Unknown | Lund University Hospital | 300 | 2018-01-23 | 2022-05-27 |
Showing 20 of 57. Sign in to see all of them.
Carcinoma, Non-Small-Cell Lung (34) · Adenocarcinoma of Lung (25) · Lung Neoplasms (14) · Adenocarcinoma, Bronchiolo-Alveolar (8) · Pancreatic Neoplasms (4) · Colonic Neoplasms (3) · Neoplasms (3) · Breast Neoplasms (2) · Bronchial Neoplasms (2) · Cholangiocarcinoma (2) · Colorectal Neoplasms (2) · Glioma (2) · Liver Neoplasms (2) · Ovarian Neoplasms (2) · Prostatic Neoplasms (2)
Neoplasms by Site (47) · Neoplasms (46) · Respiratory Tract Diseases (40) · Respiratory Tract Neoplasms (40) · Thoracic Neoplasms (40) · Lung Diseases (39) · Carcinoma, Bronchogenic (33) · Bronchial Neoplasms (32) · Neoplasms by Histologic Type (31) · Neoplasms, Glandular and Epithelial (30) · Carcinoma (28) · Adenocarcinoma (26) · Lung Neoplasms (26) · Digestive System Diseases (8) · Digestive System Neoplasms (8)
Carboplatin (11) · Paclitaxel (10) · Docetaxel (8) · Taxes (8) · Cisplatin (6) · Radiotherapy (6) · Pemetrexed (5) · Radiation (5) · Erlotinib Hydrochloride (3) · Etoposide (3) · Gefitinib (3) · Gemcitabine (3) · pembrolizumab (3) · Bevacizumab (2) · Cetuximab (2)
National Cancer Institute (NCI) (10) · Alaunos Therapeutics (2) · Geneplus-Beijing Co. Ltd. (2) · Jonsson Comprehensive Cancer Center (2) · Queen Mary University of London (2) · Roswell Park Cancer Institute (2) · Akeso (1) · Barbara Ann Karmanos Cancer Institute (1) · Beijing Anjianxi Bio-Medical Technology Co., Ltd. (1) · Capital Medical University (1) · Centre Hospitalier Universitaire de la Réunion (1) · Chinese PLA General Hospital (1) · Dana-Farber Cancer Institute (1) · ECOG-ACRIN Cancer Research Group (1) · Envita Medical Center, Inc. (1)
United States (30) · China (12) · Germany (3) · United Kingdom (3) · Canada (2) · France (2) · Italy (2) · Spain (2) · Belgium (1) · Hungary (1) · Israel (1) · Luxembourg (1) · Netherlands (1) · Poland (1) · Reunion (1)
Scott Kopetz, MD, PhD (2) · Shun Lu, MD (2) · Alessandro Inno (1) · Ann Mauer (1) · Baohui Han, MD (1) · Bruce Johnson, MD (1) · Carla R Lamb, M.D. (1) · Carlo Genova (1) · Carminia Maria Della Corte (1) · Charles Lu (1) · Charles Rudin (1) · Christophe Le Tourneau, MD (1) · Crystal Denlinger, MD (1) · David Korn, D.O., M.D. (1)
PMID 10811675, PMID 11784875, PMID 11870177, PMID 16043828, PMID 16425523, PMID 17167137, PMID 19410716, PMID 24100924, PMID 24128713, PMID 28123387, PMID 33188140, PMID 34325726, PMID 35537408, PMID 36816343, PMID 38206614, PMID 38309287, PMID 40588522, PMID 41468684, PMID 7580546, PMID 7884425
U10CA031946 (3), U10CA032102 (3), N01CM62201 (2), 2014 (1), 2018 (1), 2019 (1), N01CM17102 (1), N01CM62203 (1), N01CM62208 (1), N01CM62209 (1), P30CA016056 (1), P30CA022453 (1), R00CA134920 (1), U10CA021115 (1), U10CA045809 (1)