2 completed, 2 not yet recruiting. 2 Not applicable, 1 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Completed 1, Not yet recruiting 1 |
| Phase 1 | 1 | Not yet recruiting 1 |
| Phase 4 | 1 | Completed 1 |
Follow Sickle Cell Anemia Crisis: new trials by email Literature Review of Sickle Cell Anemia Crisis trials Research Report on Sickle Cell Anemia Crisis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Buprenorphine for the Management of Pain in Children With Sickle Cell Disease Buprenorphine Buccal Film [Belbuca] - Sickle Cell Disease (SCD), Sickle Cell Disease Vaso-occlusive Crisis | Phase 1 | Not yet recruiting | Natasha Archer | 25 | 2027-01-01 | 2026-11-04 |
| Hypoxic Red Blood Cells in Sickle Cell Anemia Hemanext ONE System, Conventional RBCs - Sickle Cell Anaemia, Sickle Cell Anemia Crisis | Not applicable | Not yet recruiting | Hemanext | 48 | 2026-11-30 | 2026-11-02 |
| Hyperbaric Oxygen Therapy in Sickle Cell Pain hyperbaric oxygen therapy - Vaso-occlusive Crisis, Sickle Cell Anemia Crisis | Not applicable | Completed | University of Nebraska | 8 | 2022-09-01 | 2026-07-28 |
| Does IV Acetaminophen Reduce Opioid Requirement in Pediatric Patients With Acute Sickle Cell Crises? Acetaminophen, Normal saline - Sickle Cell Anemia Crisis | Phase 4 | Completed | Newark Beth Israel Medical Center | 71 | 2018-02-20 | 2021-04-02 |
Vaso-Occlusive Crises (4) · Anemia, Sickle Cell (2) · Acute Pain (1) · Hemoglobin SC Disease (1)
Anemia (4) · Anemia, Hemolytic (4) · Anemia, Hemolytic, Congenital (4) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4) · Genetic Diseases, Inborn (4) · Hematologic Diseases (4) · Hemic and Lymphatic Diseases (4) · Hemoglobinopathies (4) · Anemia, Sickle Cell (2) · Neurologic Manifestations (1) · Pain (1) · Pathological Conditions, Signs and Symptoms (1) · Signs and Symptoms (1)
Acetaminophen (1) · Buprenorphine (1) · Hyperbaric Oxygenation (1) · Saline Solution (1) · Sodium Chloride (1)
Hemanext (1) · Natasha Archer (1) · Newark Beth Israel Medical Center (1) · University of Nebraska (1)
United States (4)
Biree Andemariam, MD (1) · Cena Tejani, MD (1) · Jeff S Cooper, MD (1) · Laurel Omert, MD, FACS (1) · Natasha Archer, MD (1)